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A design
t
o manufacture polyamide reverse osmosis membrane using molecular layer-by-layer deposition
T
hin-film composite polyamide membranes, are the basis for modern commercial reverse osmosis (RO) membranes. These membranes are created through interfacial polymerization (IP) involving a trifunctional acid chloride (e.g., trimesoyl chloride, TMC, dissolved in an organic solvent) and a difunctional amine (e.g., m-phenylenediamine, MPD, dissolved in...
Published: 5/30/2025
|
Inventor(s):
Samarpan Deb Majumder
,
Xi
t
ong Liu
Keywords(s):
Category(s):
T
echnology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
,
T
echnology Classifications > Industrial or Consumer Tech > Industrial Manufacturing
Robo
t
-Aided System And Method For Diagnosis Of Autism Spectrum Disorder
Sensory abnormali
t
ies are reported to be central to autistic experience. The symptoms include hyposensitivity, hypersensitivity, multichannel receptivity, processing difficulties and sensory overload. Given the intensive and cumbersome nature of current methods of diagnosis, there is a need of behavior-based approach to identify the children at risk...
Published: 5/30/2025
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Inventor(s):
Chung Hyuk Park
,
Hifza Javed
Keywords(s):
Category(s):
T
echnology Classifications > Diagnostics
,
T
echnology Classifications > Medical Devices > Therapeutic Devices
T
ampa Neuromapping Depth Electrode
Advan
t
ages Combines recording and stimulation in a single device Reduces brain penetration and surgery time Lowers risk of hemorrhage, infection, and brain shift Enables precise brain mapping and real-time stimulation Summary Deep Brain Stimulation (DBS) helps patients with movement disorders like Parkinson’s disease by sending electrical...
Published: 5/30/2025
|
Inventor(s):
Oliver Flou
t
y
,
Yarema Bezchlibnyk
,
Vishal Bharmauria
,
Nour Shaheen
,
Brian Dalm
,
Can Sarica
,
Ma
t
thew Howard
,
Hiro
t
o Kawasaki
,
Mario Zana
t
y
,
Alex Green
,
Andres Lozano
Keywords(s):
Category(s):
T
echnology Classifications > Medical > Neuroscience
Engineering Asymme
t
rically Glycosylated IgG Antibodies
Applica
t
ion A novel method to develop asymmetrically glycosylated therapeutic monoclonal IgG antibodies for preventing and treating diseases like cancer, infectious diseases, and autoimmune disorders. Key Benefits Different IgG antibody glycoforms can be produced, each with its unique effector functions and biological and therapeutic effects. Potential...
Published: 5/30/2025
|
Inventor(s):
Eric J. Sundberg
,
Jona
t
han Du
,
T
ala Azzam
Keywords(s):
An
t
ibodies
,
Immunology and Inflamma
t
ion Treatments
,
Microbiology and Infec
t
ious Disease Treatments
,
Oncology
T
reatments
Category(s):
T
echPub Algolia > Therapeutics
Companion Diagnos
t
ic for Immunomodulatory Repair Treatments
T
his technology is a diagnostic tool designed to help match patients to specific drugs or therapies to treat chronic ischemic heart failure. The platform focuses on immune cells called macrophages, which play a crucial role in the body's response to injury and disease. By promoting a specific type of macrophage known to aid healing, this system...
Published: 5/30/2025
|
Inventor(s):
S
t
even Goldman
,
Daniel Benson
,
Adrian Grijalva
,
Jordan Fink
,
Jordan Lancas
t
er
,
Jennifer Koevary
,
Simar Singh
Keywords(s):
Category(s):
T
echnology Classifications > Life Sciences > Diagnostics
,
T
echnology Classifications > Research Tools > Screening assays
,
T
echnology Classifications > Healthcare Portfolios > Heart and Vascular
RNA Binding Mo
t
if 3 (RBM3) Overexpressing Transgenic Mouse
Advan
t
ages • RBM3 upregulation reverses multiple tau phosphorylations post-TBI • Novel RBM3 Overexpressing Transgenic Mouse Model allows researchers to study the effects of RBM3 activation on tissue function, brain function, and brain injury Summary Traumatic brain injury (TBI) not only causes immediate neuronal damage but also...
Published: 5/30/2025
|
Inventor(s):
T
ravis Jackson
Keywords(s):
Animal Models
,
Neuroscience
Category(s):
T
echnology Classifications > Research Tools/Copyright > Animal Models
,
T
echnology Classifications > Medical > Neuroscience
,
T
echnology Classifications > Medical > Biotechnology
Me
t
hod for Co-Localizing Two Proteins on the Inside of the Cell Membrane in Yeast
Advan
t
ages Localization of protein interactions at the cell membrane offers a more physiologically relevant model Improved screening by minimizing off-target interactions Broadly applicable and accessible tools Summary Protein-protein interactions involving membrane proteins are notoriously difficult to study under physiologically relevant conditions....
Published: 5/30/2025
|
Inventor(s):
Lawrence S
t
ern
,
Michael Nelson
Keywords(s):
Drug Discovery
Category(s):
T
echnology Classifications > Medical > Cell & Tissue Engineering
,
T
echnology Classifications > Medical > Medical Diagnostics
,
T
echnology Classifications > Medical > Biomaterials
T
ransgenic Foxc2-tdTomato Overexpressing Mouse Model for Study and Screening of Lymphatic Valve Development
Advan
t
ages Tissue specific Foxc2 expression with integrated tdTomato fluorescent reporter enables precise spatiotemporal visualization Enables monitoring of lymphatic valve development 1:1 co-expression of Foxc2 and tdTomato, overcoming expression variability characteristic associated with of IRES-based or viral delivery systems Single-vector...
Published: 5/30/2025
|
Inventor(s):
Joshua Scallan
Keywords(s):
Animal Models
Category(s):
T
echnology Classifications > Research Tools/Copyright > Animal Models
Syn
t
hesis of Non-steroidal Anti-Inflammatory Compounds to Promote Wound Healing
Graph shows
t
he average skin punch biopsy weight of mice treated topically with nitrogen mustard (NM) to induce skin inflammation. Mice additionally treated with polyamine-imidazole conjugates showed a marked decrease in skin inflammation. Invention Summary: Non-steroidal Anti-Inflammatory drugs (NSAIDs) are widely available for over-the-counter...
Published: 5/30/2025
|
Inventor(s):
Jeffrey Laskin
,
Ned Heindel
,
Chris
t
ophe Guillon
Keywords(s):
Category(s):
T
echnology Classifications > Therapeutics
,
T
echnology Classifications > Healthcare & Life Sciences
Repurposed Recep
t
or Blocker for the Treatment of PTSD
Applica
t
ion Use of neurokinin 3 receptor antagonist, osanetant, for the prevention and treatment of post-traumatic stress disorder (PTSD) and other anxiety disorders. Key Benefits Utilizes a repurposed drug that is safe for human use. Potential to treat specific PTSD symptoms better than antidepressants. Market Summary Post-traumatic stress...
Published: 5/30/2025
|
Inventor(s):
Kerry Ressler
,
Raul Andero Gali
Keywords(s):
Neurology and Pain
T
reatments
,
Repurposed Drug
Category(s):
T
echPub Algolia > Therapeutics
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