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DESIGN OF A UNIVERSAL INFLUENZA VACCINE CANDIDATES VIA ANTIGEN REORIENTATION

DESIGN OF A UNIVERSAL INFLUENZA VACCINE CANDIDATES VIA ANTIGEN REORIENTATION Researchers at Stanford have developed a novel universal influenza vaccine candidate. Vaccines are a major feat of biomedical innovation. Successful vaccines produce broad humoral immunity to a pathogen to prevent subsequent infection. In this vein, adjuvants are compounds...

Published: 12/5/2023 | Inventor(s): Duo Xu, Peter Kim

Keywords(s): Adjuvant, Alum, Infectious Disease, Vaccine

Category(s): Technology Classifications > Biology

CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF

CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF Researchers at Stanford have developed a new microparticle vaccine scaffold for the development of immunogenic subunit vaccines. Vaccines are one of the most important biomedical advances of the 20th century. Protein vaccines, often referred to as subunit vaccines, have proved...

Published: 8/17/2023 | Inventor(s): Peter Kim, Carolyn Bertozzi, Frances RodrÃguez-Rivera

Keywords(s): Adjuvant, Bacteria, Peptidoglycan, Vaccine

Category(s): Technology Classifications > Biology

Polypeptides and Methods for Enhancing and Balancing Monovalent or Multivalent Flavivirus Vaccines

CDC researchers have developed a potent immunogenic enhancer polypeptide useful for improving flavivirus vaccines. Flaviviruses such as dengue virus (1, 2, 3 and 4), Japanese encephalitis virus, Murray Valley encephalitis virus, St. Louis encephalitis virus, yellow fever virus and tick-borne encephalitis virus are a great burden on public health. ...

Published: 7/25/2024 | Inventor(s): Holly Hughes, Gwong-Jen Chang

Keywords(s): ADJUSTMENT, adjuvant, Adjuvant-like, BCXXXX, Boost, BOOSTING, CD4, CDC Docket Import, CDC Docket Import CDC Prosecuting, Cell, DB4BXX, DB4XXX, DC1XXX, DC5BXX, DC5XXX, DCXXXX, DDXXXX, DENGUE, DENGUE FEVER, Dengue Vaccine, Dengue-1, Dengue-2, Dengue-Like, DXXXXX, Epitope, Flavivirus, FLAVIVIRUSES, Identification, in vivo, JAPANESE ENCEPHALITIS VIRUS, Listed LPM Houze as of 4/15/2015, Mosquito, Mosquitoes, Nile, OID-NCEZID-DVBD, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PRIMER, T, THEREOF, Tick-Bone, TICK-BORNE, UBXXXX, Vaccine, Vaccine Design, VACCINE DEVELOPMENT, VBXXXX, Vector-borne, Vector-borne diseases, virus, VLXXXX, VOXXXX, WAXXXX, West, WIXXXX, WJXXXX, WMXXXX, XCXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Rare / Neglected Diseases, Application > Vaccines, Application > Therapeutics, Application > Research Materials, Application > Consumer Products, TherapeuticArea > Infectious Disease

CD40 Ligand: Adjuvant for Enhanced Immune Response to Respiratory Syncytial Virus

CDC researchers have developed methods and adjuvants for enhancing a subject's immune response to respiratory syncytial virus (RSV) by inclusion of a CD40 binding protein. RSV has long been recognized as a major respiratory tract pathogen of infants, as well as older children and the elderly. Established, successful methods for preventing RSV are...

Published: 4/8/2024 | Inventor(s): Larry Anderson, Michael Brown, Ralph Tripp

Keywords(s): adjuvant, CD40, CD40L, CDC Docket Import, CDC Docket Import CDC Prosecuting, Costimulation, COSTIMULATORY, DB4BXX, DB4XXX, DBXXXX, DC1XXX, DC5BXX, DC5XXX, DCXXXX, DXXXXX, LIGAND, OID-NCIRD-DVD, respiratory, RSV, RSV virus, Synctial, Vacccination, Vaccine, virus, VLXXXX, WJXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Vaccines

Oxygen as an immunological adjuvant or co-adjuvant to reinforce vaccines and immunotherapies

INV-21019 Background Vaccines are crucial to fight infections, cancer, and autoimmune conditions as they aid in generating immune response before the onset of the disease. Vaccines developed with purified molecules often do not stimulate an effective immune response as compared to the immune response generated against natural infection. Hence, adjuvants...

Published: 9/10/2024 | Inventor(s): Sidi Bencherif, Thibault Colombani

Keywords(s): Adjuvant, Biomaterials, Co-adjuvant, Oxygen, Vaccines

Category(s): -Pharmaceutical Composition, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery