Search Results - elias+sayour

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Cancer Vaccine to Treat Melanoma and Osteosarcoma

Stimulates the Immune System to Respond to a Major Surface Antigen on Cancerous Cells This cancer vaccine stimulates the production of antibodies against a cell surface antigen common to both melanoma and osteosarcoma tumors and works in conjunction with chemotherapy. Melanoma is an aggressive form of skin cancer that’s highly metastatic at later...

Published: 2/22/2024 | Inventor(s): Rowan Milner, Mathew Cascio, Elias Sayour, Joanne Lagmay, Bikash Sahay, Marc Salute

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Category(s): Technology Classifications > Veterinary > Therapeutics, Technology Classifications > Human Health Care > Therapeutics

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

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Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Nanoparticle RNA Vaccine to Treat Gliomas

Encodes for Specific Antigens to Promote Anti-Tumor Immunity This cancer vaccine activates antigen-presenting cells and induces anti-tumor immune system activity for the treatment of diffuse intrinsic pontine gliomas (DIPG). DIPG tumors originate in the pons, an area of the brainstem controlling vital body functions such as breathing and heart rate....

Published: 7/30/2021 | Inventor(s): Elias Sayour, James McGuiness, Hector Mendez-Gomez, Duane Mitchell

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Category(s): Technology Classifications > Human Health Care > Therapeutics

Nanoparticle RNA Vaccine That Targets Slow-Cycling, Treatment-Resistant Cancer

Activates T-Cell Recognition of Tumor-Initiating Stem Cells in Mouse Model of Glioma This nanoparticle vaccine targets the slow-cycling, treatment-resistant, cancer stem cells to improve efficiency of anti-cancer drugs, thereby improving disease prognosis. Despite major developments in the field of anti-cancer therapies, tumor recurrence and metastasis...

Published: 2/13/2024 | Inventor(s): Elias Sayour, Loic Deleyrolle, Hector Mendez-Gomez, Sadeem Qdaisat, Duane Mitchell

Keywords(s): Cancer, cancer stem cells, Immunotherapy, Nanoparticles, Vaccine development

Category(s): Technology Classifications > Human Health Care > Therapeutics

Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers

Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert

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Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources

All-Fiber Multicore Fiber Laser Devices

Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li

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Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources