Search Results - technology+classifications+%3e+chemical+processes+and+synthesis

53 Results Sort By:
Photoactivated Selective Release (PHASR) of Droplets from Microwell Arrays
A photoresponsive polymer layer that can be integrated into microfluidic devices for selective release of unique droplets Problem: Droplet microfluidics are used for single molecule detection and analysis, such as isolation of protein biomarkers for monitoring of disease progression. Current techniques for recovering unique molecules or cells from droplet...
Published: 8/2/2024   |   Inventor(s): Daeyeon Lee, Junhyong Kim, Yongwon Choi, Syung-Hun Han
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Microfluidics, Nanotechnology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Research Tools & Reagents
Biocompatible, Reversible, and Strong Multilayered Tape for Advanced Wound Care
A hydrogel-based adhesive with a hydrophobic backing layer protects it from exposure to water and offers painless removal and easy repositioning. Problem: Reversible adhesives have gained popularity in industries with a growing emphasis on reducing waste and improving sustainability. Previously, the inventors have developed a strong and reversible adhesive...
Published: 7/23/2024   |   Inventor(s): Shu Yang, Baohong Chen, Alexander Tucker
Keywords(s): Bioengineering, Hydrogels, Platform Technology, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials
Targeted Organ or Multiple Organ Delivery of mRNA with Ionizable Amphiphilic Janus Dendrimers
A library of easily synthesized ionizable amphiphilic Janus dendrimer (IAJD) compounds that deliver mRNA either to targeted organs or multiple organs, depending on the IAJD design. Problem: Four-component lipid nanoparticles (LNPs) are the benchmark synthetic vector for the delivery of mRNA. Despite their high biosafety, low toxicity, and immunogenicity,...
Published: 7/23/2024   |   Inventor(s): Virgil Percec, Drew Weissman, Juncheng (Luke) Lu, Elena Atochina-Vasserman, Devendra Maurya, Dipankar Sahoo
Keywords(s): Drug Delivery, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Vaccines
Single-Step Wettability Patterning for Microfluidic Generation of Emulsions
Method to transfer wettability properties of a mold to microfluidic devices, defining hydrophobic/hydrophilic regions through variable perfluoropolyether concentration. Problem: Current wettability patterning methods involve sequentially flowing chemicals into channels, blocking areas where treatment is not desired. These multi-step methods are labor...
Published: 7/23/2024   |   Inventor(s): Daeyeon Lee, David Issadore, Jingyu Wu
Keywords(s): Microfluidics
Category(s): Technology Classifications > Chemical Processes and Synthesis
Scalable and Eco-Friendly Manufacturing of Tunable Heterogeneous Nanoparticle Films
A scalable heterogeneous nanoparticle film with controllable manufacturing methods with tunable properties that could be useful for a variety of applications. Problem: Current techniques for manufacturing polymer-infiltrated nanoparticle films (PINFs) include immersion in polymer melts, capillary rise infiltration, and solvent-driven infiltration....
Published: 7/9/2024   |   Inventor(s): Daeyeon Lee, Baek Min Kim
Keywords(s): Nanotechnology, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Hardware & Components, Technology Classifications > Materials
Base Metal Catalysts For Cyclic Conjugated Polymer Formation
A class of base metal catalysts (as opposed to expensive platinum and heavier group metals) with facile preparation methods for cyclic conjugated polymer synthesis. Problem: There is a demand for facile synthesis and purification of cyclic conjugated polymers due to their applications as lubricants, conductors, or materials with high refractive indices....
Published: 1/29/2024   |   Inventor(s): Daniel Mindiola, John Russell
Keywords(s): Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials, Technology Classifications > Research Tools & Reagents
PET Radiotracers for Diagnosis and Patient Stratification of Neurodegenerative Disorders
Small molecules that bind to alpha-synuclein deposition and can be used for PET imagining in patients with synucleinopathies Problem: Imaging alpha-synuclein (αS) using noninvasive techniques such as positron emission tomography (PET) can help with the early diagnosis of synucleinopathies. Previous PET radiotracers suffer from low binding affinity...
Published: 6/6/2024   |   Inventor(s): Robert Mach, E. James Petersson
Keywords(s): Imaging Agents, Neurodegenerative Diseases, Radiology, Small Molecule
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Diagnostics, Technology Classifications > Imaging, Technology Classifications > Research Tools & Reagents
Low Toxicity Antimicrobial Peptides To Overcome Antibiotic Resistance
Combining naturally occurring peptides by hybridizing them with known active peptides to synthesize effective antimicrobial peptides with minimal cytotoxicity. Problem: Antibiotic resistance is a significant concern that poses a potential risk of increased harm from future infectious diseases. Consequently, antimicrobial peptides (AMPs) are regarded...
Published: 11/3/2023   |   Inventor(s): Cesar de la Fuente-Nunez, Ravi Radhakrishnan, Vani Xavier de Oliveira Junior, Marcelo Der Torossian Torres, Yiming Wang, Cibele Nicolaski Pedron
Keywords(s): Infectious Disease, Protein/Peptide (Non-Antibody)
Category(s): Technology Classifications > Chemical Processes and Synthesis
Stable Biological Membrane Mimetic For Enhanced Protein Recruitment
Synthetic biological alternative to natural lipids for conjugation with nitrilotriacetic acid (NTA) for enhanced His-tagged protein interaction and long-term stability. Problem: Biomimetic lipid vesicles, such as liposomes, have multiple biotechnology and drug delivery applications as their lipid bilayer innately interacts with natural cell membranes....
Published: 10/16/2023   |   Inventor(s): Virgil Percec, Qi Xiao, Matthew Good
Keywords(s): Bioengineering, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Research Tools & Reagents
Easily Fabricated Polymer Brushes For pH-Mediated Nanoparticle (NP) Control
A polymer brush coating on a substrate made through block copolymer coating and exfoliation for pH-mediated nanoparticle sorting, transport, and diffusion. Problem: NP-based technologies in fields such as biotherapeutics, separation, and purification require precise control of nanoparticle transport, absorption, and diffusion. Polymer brushes exhibit...
Published: 10/16/2023   |   Inventor(s): Yechan Kim, Russell Composto, Karen Winey
Keywords(s): Electronic Materials, Microfluidics, Optics & Photonics , Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Research Tools & Reagents, Technology Classifications > Materials
1 2 3 4 5 6