Search Results - protein+delivery

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Telodendrimer Nanoparticles for Protein Delivery
A nanoparticle-based method for enhanced delivery of protein/peptide therapeutics. Background: Biologics, for example protein and peptide-based therapeutics, have poor in vitro shelf stability and in vivo enzymatic stability, which lead to short blood circulating time and contribute to immunogenicity. In addition, biologics are impermeable to biological...
Published: 7/24/2023   |   Inventor(s): Juntao Luo, Xu Wang, Changying Shi, Alexa Bodman, Walter Hall
Keywords(s): cancer therapy, lipidoids, nanoparticles, protein delivery, telodendrimers
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology
Materials For More Safely And Efficiently Generating Reprogrammed Cells For Cell Therapy
Eliminate Toxicity to Host Cell While Maintaining Injection CapabilityThese new nuclear-protein-delivery materials provide more efficient cellular reprogramming that, by eliminating need for genetic modification, is more acceptable to regulatory agencies. These reprogrammed cells can be used in regenerative therapy for genetic, metabolic and degenerative...
Published: 6/27/2021   |   Inventor(s): Shouguang Jin, Candace Bichsel-Tebbenkamp
Keywords(s): Dedifferentiation, induced pluripotent stem cell, Protein Delivery, Reprogramming, Stem cell differentiation, Type III secretion system
Category(s): Technology Classifications > Human Health Care > Drug Delivery