Search Results - cancer+therapy

3 Results Sort By:
Win Motif Inhibitors for the Treatment of Cancer
A novel approach to the development of new and effective cancer treatment options. Background: The Mixed Lineage Leukemia 1 (MLL1) protein is a member of the SET1 family of proteins. Mutations of the MLL1 core complex leads to excessive di- and trimethylation of H3K4 which alters gene regulation. This has been linked to certain types of leukemia,...
Published: 7/11/2023   |   Inventor(s): Michael Cosgrove, Nilda Alicea-Velazquez, Stephen Shinsky
Keywords(s): #SUNYresearch, cancer therapy, Technologies
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Telodendrimer Nanoparticles for Protein Delivery
A nanoparticle-based method for enhanced delivery of protein/peptide therapeutics. Background: Biologics, for example protein and peptide-based therapeutics, have poor in vitro shelf stability and in vivo enzymatic stability, which lead to short blood circulating time and contribute to immunogenicity. In addition, biologics are impermeable to biological...
Published: 7/24/2023   |   Inventor(s): Juntao Luo, Xu Wang, Changying Shi, Alexa Bodman, Walter Hall
Keywords(s): cancer therapy, lipidoids, nanoparticles, protein delivery, telodendrimers
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology
Cancer Therapeutic with Increased Efficacy and Reduced Side Effects
Uses Small Drug-Like Molecules to Prevent Cancer Cell ProliferationThis breakthrough approach to treating cancer is efficacious and has limited side effects. Cancer is a leading cause of death in the United States, accounting for one in four deaths annually, according to the American Cancer Society. An estimated 595,600 Americans will die of cancer-related...
Published: 6/27/2021   |   Inventor(s): Peter Stacpoole, David Ostrov, Arun Srivastava
Keywords(s): breast cancer, Cancer Therapy, Clinical trials, Colon Cancer, PDK2, Structure-based Drug Design
Category(s): Technology Classifications > Human Health Care > Therapeutics