Search Results - life+science+research+tools+%3e+other+reagents

18 Results Sort By:
Compounds and Methods for Inducing UCP1 Expression (UCLA Case No. 2019-272)
UCLA researchers in the Department Human Genetics have identified small molecules that induce UCP1 expression and thermogenic mitochondrial activity in adipocytes, providing a novel class of potential therapeutics for obesity and related conditions. BACKGROUND: Obesity affects more than 93 million Americans and continues to rise in prevalence. Modulating...
Published: 4/14/2026   |   Updated: 3/26/2026   |   Inventor(s): Laurent Vergnes, Karen Reue
Keywords(s):  
Category(s): Therapeutics > Metabolism And Endocrinology, Therapeutics > Cardiovascular, Life Science Research Tools > Other Reagents
A Solid-Phase Compatible Dialkoxydiphenylsilane (DADPS) Reagent for Chemoproteomics (UCLA Case No. 2023-017)
UCLA researchers in the Department of Biological Chemistry have developed two novel fluorenylmethyl carbamate functionalized dialkoxydiphenylsilane (FMOC-DADPS) reagents that provide unprecedented compatibility with solid-phase chemistry, enabling higher yield and purity in the synthesis of DADPS-based chemoproteomics capture reagents. BACKGROUND:...
Published: 1/7/2026   |   Updated: 1/7/2026   |   Inventor(s): Keriann Backus
Keywords(s):  
Category(s): Life Science Research Tools > Other Reagents, Life Science Research Tools > Research Methods
Covalent Inhibitors and High Throughput Screening Platform for Inhibitor Discovery for Caspase-10 and Related Caspases (UCLA Case No. 2025-130)
UCLA researchers in the Department of Biological Chemistry have developed a high throughput screening platform to identify state-specific protease inhibitors, enabling identification of two inhibitor classes that preferentially show zymogen-directed caspase-10 inhibition. BACKGROUND: Caspases are a conserved family of cysteine proteases that play important...
Published: 2/2/2026   |   Updated: 9/18/2025   |   Inventor(s): Keriann Backus
Keywords(s):  
Category(s): Therapeutics > Inflammation And Inflammatory Diseases, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Other Reagents, Life Science Research Tools > Research Methods
Stain-Free, Rapid, and Quantitative Viral Plaque Assay Using Deep Learning and Holography (Case No. 2022-326)
Intro Sentence: UCLA researchers in the Department of Electrical and Computer Engineering have developed a rapid and stain-free quantitative assay using lens-free holography and deep learning to efficiently and cost-effectively determine the presence of viral plaque-forming units (PFUs) in samples. Background: A broad range of viruses have caused...
Published: 2/14/2025   |   Updated: 8/11/2023   |   Inventor(s): Aydogan Ozcan, Yuzhu Li, Tairan Liu
Keywords(s): Antiviral Drug, Artifical Intelligence (Machine Learning, Data Mining), Assay, Bioassay, Computer Aided Learning, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Digital Holography, Electrical, Electrical Brain Stimulation, Electrical Breakdown, Electrical Engineering, Electrical Impedance, Electrical Load, Electrical Load Equation Of State, Electrical Resistance And Conductance, Electrical Resistivity And Conductivity, Holography, Immunoassay, Immunoassay Sense (Molecular Biology), Lentivirus Viral Vector, Machine Learning, Machine Learning Autonomous Car Gradient Descent, Machine Learning Pain Management, Machine Learning Particulates Global Climate Model, Network Analysis (Electrical Circuits), Perceptual Learning, Plasmid Trabecular Meshwork Aqueous Humour Viral Vector, Targets And Assays, Transcutaneous Electrical Nerve Stimulation, Transfection Viral Vector, Unsupervised Learning , Viability Assay, Viral Delivery Systems, Viral Envelope, Viral Load
Category(s): Diagnostic Markers, Diagnostic Markers > Targets And Assays, Electrical, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Software & Algorithms > Artificial Intelligence & Machine Learning
2023-102 A Dynamic Cholesteric Liquid Crystal for Organoid, Spheroid, 3D Cell Aggregate Manufacturing
Summary: UCLA and University of Connecticut researchers have engineered a novel liquid-crystal-based biomaterial with a simple fabrication process for organoid, spheroid and 3D cell aggregate manufacturing that enables rapid cell growth. Background: The current waiting list for people who need a lifesaving organ transplant is over 100,000 cases...
Published: 7/25/2025   |   Updated: 2/7/2023   |   Inventor(s): Paul Weiss, Amir Nasajpour, Ali Tamayol, Mohamadmahdi Samandari
Keywords(s): 3D biofabrication, 3D Printing, Biocompatibility, biocompatible, Biomaterial 3D Printing, biomedical implantation, Cell and tissue culture, Cell Culture, cell-extracellular matrix (ECM), cellular aggregates, Cellular agriculture, Cholesterol, cholesteryl ester liquid crystals (CLCs), Cultured meat, Electrode 3D Printing, liquid crystal, liquid crystal nanofibers, mesogens, Organ Transplant, organogenesis, scaffolds, self-assemble, Stem Cells / Regenerative Medicine, Tissue Engineering
Category(s): Chemical, Chemical > Polymers, Materials, Materials > Functional Materials, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Medical Devices, Medical Devices > Surgical Tools, Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
2021-016 Liquid Crystal-based Scaffolds for Cell-cultured Meat Production
Summary: UCLA researchers in the Department of Mechanical and Materials Engineering have developed a nonwoven CLC (cholesteryl ester liquid crystals) electrospun scaffold to enhance myofibril formation in vitro. Background: Cholesteryl ester liquid crystals (CLCs) are promising biomaterials for the development of dynamic and responsive interfaces...
Published: 7/25/2025   |   Updated: 6/7/2022   |   Inventor(s): Amir Nasajpour, Paul Weiss
Keywords(s):  
Category(s): Chemical > Polymers, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents
2021-309-METHODS OF USING SHAPED PARTICLES IN FLOW CYTOMETERS FOR ASSAYS ON B CELLS AND T CELLS
Summary: UCLA researchers in the Department of Bioengineering have developed a platform to sort single cells based on their secreted product at high throughput using commonly accessible lab infrastructure, i.e., flow cytometers. Background: Techniques to sort single cells based on secreted products have the potential to accelerate the development...
Published: 7/17/2025   |   Updated: 3/21/2022   |   Inventor(s): Dino Di Carlo, Joseph de Rutte, Robert Dimatteo, Maani Archang, Robert Damoiseaux, Doyeon Koo
Keywords(s): Antibody, B Cell, Bioassay, Cell Counting/Imaging, Cellular Differentiation, Cytometry, Flow Cytometry, Fluorescence, Hybridoma Technology, Secretory Component, T Cell, Targets And Assays
Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies, Life Science Research Tools > Cell Lines, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies
2020-849-LOW-COST, FAST AND COMPACT EXHALED BREATH CONDENSATE TECHNOLOGY
SUMMARY: UCLA researchers have developed a low-cost method for non-invasive infectious disease testing that can monitor large public spaces for signs of viral outbreaks. BACKGROUND: The ability to test for infectious diseases through non-invasive approaches has become even more prevalent today due to the COVID-19 pandemic. To monitor large populations...
Published: 7/17/2025   |   Updated: 10/25/2021   |   Inventor(s): Pirouz Kavehpour
Keywords(s): Diagnostic Test, Infection, Infectious Diseases, Infectivity, Medical Device, Viral Load
Category(s): Life Science Research Tools > Other Reagents, Diagnostic Markers, Therapeutics > Infectious Diseases, Therapeutics > Infectious Diseases > COVID
WNT-B-Catenin Signaling Pathway Inhibitors (UCLA Case No. 2020-371)
UCLA researchers from the Department of Pediatrics have uncovered a novel inhibitor to the Wnt/β-catenin signaling pathway.BACKGROUND:Airways in the throat play a vital role in host defense to protect mammals from airborne pathogens. This protective effect is accomplished by a specialized type of epithelium, the mucocillary epithelium, that comes...
Published: 9/18/2025   |   Updated: 4/21/2020   |   Inventor(s): Brigitte Gomperts
Keywords(s): Infectious Diseases, Life Science Research Tools, Other Reagents, Therapeutics & Vaccines
Category(s): Life Science Research Tools > Other Reagents, Therapeutics > Infectious Diseases, Therapeutics > Respiratory And Pulmonary
2011-394 Copyright: A Statistical Atlas of the Mouse Trunk Region
Summary Researchers at the University of California, Los Angeles (UCLA) have developed a comprehensive statistical atlas of the mouse trunk anatomy for use in preclinical imaging. Background Small animal imaging modalities, such as micro-CT, micro-PET, and micro-MR, are frequently used in preclinical studies. The laboratory mouse is the most widely...
Published: 2/14/2025   |   Updated: 1/16/2020   |   Inventor(s):  
Keywords(s):  
Category(s): Life Science Research Tools > Other Reagents
1 2