Search Results - other+reagents

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WNT-B-Catenin Signaling Pathway Inhibitors (UCLA Case No. 2020-371)
UCLA researchers from the Department of Pediatrics have uncovered a novel inhibitor to the Wnt/β-catenin signaling pathway.BACKGROUND:Airways in the throat play a vital role in host defense to protect mammals from airborne pathogens. This protective effect is accomplished by a specialized type of epithelium, the mucocillary epithelium, that comes...
Published: 7/17/2025   |   Inventor(s): Brigitte Gomperts
Keywords(s): Infectious Diseases, Life Science Research Tools, Other Reagents, Therapeutics & Vaccines
Category(s): Life Science Research Tools > Other Reagents, Therapeutics > Infectious Diseases
2018-022 SMALL MOLECULE MODULATORS THAT MEDIATE PINK1 AND PARKIN TRAFFICKING IN MITOCHONDRIA
UCLA researchers have developed two novel small molecule probes, MB-10 and DECA, that attenuate PINK1 and Parkin trafficking in mitochondrial in human cells that provide a new approach to elucidate the mechanisms of mitophagy.BACKGROUND:Mitophagy is an important pathway that selectively degrades dysfunctional mitochondria to keep the cell healthy. Neurodegenerative...
Published: 7/3/2025   |   Inventor(s): Carla Koehler
Keywords(s): Life Science Research Tools, Other Reagents
Category(s): Life Science Research Tools > Other Reagents
2019-336 CARBORANE-BASED HISTONE DEACETYLASE (HDAC) INHIBITORS
Carborane-Based Histone Deacetylase (HDAC) InhibitorsTech ID: 30179 / UC Case 2019-336-0SUMMARYUCLA researchers from the Department of Chemistry & Biochemistry have developed a new class of Histone Deacetylase (HDAC) inhibitors that can be tuned for isoform specificity and other properties.BACKGROUNDHistone Deacetylase (HDAC) is a ubiquitous enzyme...
Published: 7/17/2025   |   Inventor(s): Alexander Spokoyny
Keywords(s): Cns, Life Science Research Tools, Other Reagents, Therapeutics & Vaccines
Category(s): Life Science Research Tools, Life Science Research Tools > Other Reagents, Therapeutics, Therapeutics > CNS and Neurology
2018-451 ELECTROCHEMICAL FLASH FLUORINATION AND RADIOFLUORINATION
Electrochemical Flash Fluorination and RadiofluorinationSUMMARYResearchers led by Saman Sadeghi from the Department of Molecular & Medical Pharmacology at UCLA have developed a new and simple process to make fluorinated organic compounds.BACKGROUNDOrganic compounds functionalized with fluorine atoms have distinguished physical, biological, and chemical...
Published: 7/17/2025   |   Inventor(s): Seyed Saman Sadeghi Hosseini
Keywords(s): Life Science Research Tools, Medical Imaging, MRI, Other, Other Reagents, X-Ray
Category(s): Life Science Research Tools, Life Science Research Tools > Other Reagents, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Medical Devices > Medical Imaging > X-Ray
Guided Magnetic Nanospears for Targeted and High-Throughput Intracellular Delivery (UCLA Case No. 2018-436)
Guided Magnetic Nanospears For Targeted And High-Throughput Intracellular DeliverySUMMARYUCLA researchers in the Department of Chemistry & Biochemistry and Department of Molecular & Medical Pharmacology have developed novel magnetic nanostructures that can be used to carry and/or deliver biomolecular cargo intracellularly to cells.BACKGROUNDCurrent...
Published: 7/17/2025   |   Inventor(s): Steven Jonas, Hsian-Rong Tseng, Shuang Hou, Paul Weiss
Keywords(s): Drug Delivery, Life Science Research Tools, Nanoparticles, Other Reagents
Category(s): Life Science Research Tools, Life Science Research Tools > Other Reagents, Platforms > Drug Delivery, Platforms > Drug Delivery > Nanoparticles