Search Results - cytometry

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Functional Enrichment and Purification of a Therapeutically Superior Population of Cells (Case No. 2024-024)
Summary: UCLA researchers in the Departments of Bioengineering and Biological Chemistry have developed a method for identifying and enriching therapeutically useful cell sub-populations based on their secretions (SEC-seq). Background: Cell function is defined by a myriad of biomolecules that they secrete; over 3 thousand proteins are estimated to...
Published: 9/11/2024   |   Inventor(s): Dino Di Carlo, Kathrin Plath, Shreya Udani, Justin Langerman
Keywords(s): Cell Surface Receptor, Cytometry, Flow Cytometry, Functional Genomics, High-Throughput Screening, hydrogel, Microfluidics, single cell analysis, Therapeutics
Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy, Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Therapeutics > Cell Therapy
2016-219-3 SYSTEM AND METHOD FOR OPTICAL TRANSIENT LIQUID MOLDING OF MICROPARTICLES AND USES FOR THE SAME
SUMMARY: The Di Carlo group at UCLA has invented a microparticle that enables analysis of adherent cells via flow cytometry with high throughput. BACKGROUND: Traditional flow cytometry is a fluorescence-based technique used to characterize cells on a molecular level usually suspended in a fluid. However, many cells are inherently attached to matrix...
Published: 7/19/2023   |   Inventor(s): Dino Di Carlo, Chueh-Yu Wu
Keywords(s): Cell Counting/Imaging, Cytometry, Diagnostic Platform Technologies (E.G. Microfluidics), Flow Cytometry, Life Science Research Tools, Microfluidics, Microfluidics And Mem's, Targets And Assays
Category(s): Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microfluidics And Mems, Platforms > Diagnostic Platform Technologies
2021-309-METHODS OF USING SHAPED PARTICLES IN FLOW CYTOMETERS FOR ASSAYS ON B CELLS AND T CELLS
Summary: UCLA researchers in the Department of Bioengineering have developed a platform to sort single cells based on their secreted product at high throughput using commonly accessible lab infrastructure, i.e., flow cytometers. Background: Techniques to sort single cells based on secreted products have the potential to accelerate the development...
Published: 7/19/2023   |   Inventor(s): Dino Di Carlo, Joseph de Rutte, Robert Dimatteo, Maani Archang, Robert Damoiseaux, Doyeon Koo
Keywords(s): Antibody, B Cell, Bioassay, Cell Counting/Imaging, Cellular Differentiation, Cytometry, Flow Cytometry, Fluorescence, Hybridoma Technology, Secretory Component, T Cell, Targets And Assays
Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies, Life Science Research Tools > Cell Lines, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies
Real-Time Colorimetric and Fluorescent Imaging in Live Cells
Description of TechnologyInnovators at Michigan State University (MSU) have developed a novel method for dynamic tracking of proteins in living cells. MSU's novel method tags proteins with a wide variety of colors, enabling several different proteins to be detected and tracked simultaneously. Using this method, multiple color variants are genetically...
Published: 2/17/2023   |   Inventor(s): Babak Borhan, James Geiger, Wenjing Wang, Chrysoula Vasileiou, Kin Sing Lee, Tetyana Berbasova
Keywords(s): Cytometry, Fluorescence, Fluorescent Dyes, Fluorescent Label, Green Fluorescent Protein, High Throughput Assay
Category(s): Biotechnology