Search Results - keriann+backus

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Custom Isobaric Tandem Mass Spectrometry Quantitative Chemoproteomics Enabled by Dialkoxydiphenylsilane (DADPS) Capture Reagents (UCLA Case No. 2023-113)
UCLA researchers in the Department of Biological Chemistry have developed a chemoproteomics-based method for improved and efficient protein and drug studies. BACKGROUND: Quantitative proteomics is a method scientists use to find out how much of each protein is in a sample. It is used to compare protein levels in different situations. This information...
Published: 1/7/2026   |   Inventor(s): Keriann Backus
Keywords(s):  
Category(s): Life Science Research Tools > Mass Spectrometry
A Solid-Phase Compatible Dialkoxydiphenylsilane (DADPS) Reagent for Chemoproteomics (UCLA Case No. 2023-017)
UCLA researchers in the Department of Biological Chemistry have developed two novel fluorenylmethyl carbamate functionalized dialkoxydiphenylsilane (FMOC-DADPS) reagents that provide unprecedented compatibility with solid-phase chemistry, enabling higher yield and purity in the synthesis of DADPS-based chemoproteomics capture reagents. BACKGROUND:...
Published: 1/7/2026   |   Inventor(s): Keriann Backus
Keywords(s):  
Category(s): Life Science Research Tools > Other Reagents, Life Science Research Tools > Research Methods
Silyl Ether Enables Chemoproteomic Interaction and Target Engagement (SEE-CITE) (UCLA Case No. 2024-194)
UCLA researchers from the Department of Biological Chemistry have developed a chemoproteomic platform for high-coverage, site-specific mapping of small-molecule–protein interactions using a cleavable silyl ether–based photoaffinity probe design. BACKGROUND: Small molecule drugs rely on specific and selective interactions with protein targets...
Published: 11/4/2025   |   Inventor(s): Keriann Backus
Keywords(s):  
Category(s): Life Science Research Tools > Mass Spectrometry, Life Science Research Tools > Research Methods, Therapeutics > Oncology
Covalent Inhibitors and High Throughput Screening Platform for Inhibitor Discovery for Caspase-10 and Related Caspases (UCLA Case No. 2025-130)
Contact UCLA Technology Development Group to learn more.
Published: 11/20/2025   |   Inventor(s): Keriann Backus
Keywords(s):  
Category(s): Life Science Research Tools