Search Results - life+science+research+tools+%3e+microfluidics+and+mems

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High-Throughput Cargo Delivery Into Live Cells Using Photothermal Platforms (Case No. 2013-158)
Summary: UCLA researchers in the Department of Mechanical Engineering have developed a photothermal platform for precisely opening a cell membrane to deliver cargo into cells. Title: High-Throughput Cargo Delivery Into Live Cells Using Photothermal Platforms Background: Transferring cargo like proteins, nucleotides and particles into cells is valuable...
Published: 7/17/2024   |   Inventor(s): Pei Yu Chiou, Michael Teitell, Ting Hsiang Wu, Yi-Chien Wu
Keywords(s): cell engineering, cellular, delivery system, Gene delivery, Laser, Microbiology, Micropump
Category(s): Electrical > Mems, Life Science Research Tools > Microfluidics And Mems
Core-Shell Hydrogel Particles With Tunable Porosity for Digital Nucleic Acid Assays (Case No. 2023-058)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel method to perform ultra-high sensitivity, low-cost nucleic acid amplification assays utilizing porous microdroplets. Background: Nucleic acid concentration measurement is essential in biological research and diagnostics. The 2020 pandemic underscored the importance...
Published: 8/30/2023   |   Inventor(s): Dino Di Carlo, Michael Thomas Alesse Bogumil
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Flow Cytometry, Medical diagnostics
Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Targets And Assays, Chemical > Emulsions, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies
Robot-On-A-Dish: Automating Cellular Sorting and Analysis via Robotic Motor-Driven Flow
­Summary: UCLA researchers in the Department of Bioengineering have built a new cell sorting system that can handle and maintain linear flow control for a broad range of mesoscale particles in fluids. Background: The global market for drug discovery technologies was valued at $65.3 billion in 2019, and it is expected to grow at a CAGR of 9.6%....
Published: 7/19/2023   |   Inventor(s): Dino Di Carlo, Reem Khojah
Keywords(s): Cell Counting/Imaging, Content Analysis, Diagnostic Markers & Platforms, Drug Discovery, Flow Cytometry, Flow Device, High-Throughput Screening, mesoscale, mesoscale particles, Robotic liquid handling
Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods, Chemical, Chemical > Instrumentation & Analysis, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microfluidics And Mems
2016-219-3 SYSTEM AND METHOD FOR OPTICAL TRANSIENT LIQUID MOLDING OF MICROPARTICLES AND USES FOR THE SAME
SUMMARY: The Di Carlo group at UCLA has invented a microparticle that enables analysis of adherent cells via flow cytometry with high throughput. BACKGROUND: Traditional flow cytometry is a fluorescence-based technique used to characterize cells on a molecular level usually suspended in a fluid. However, many cells are inherently attached to matrix...
Published: 7/19/2023   |   Inventor(s): Dino Di Carlo, Chueh-Yu Wu
Keywords(s): Cell Counting/Imaging, Cytometry, Diagnostic Platform Technologies (E.G. Microfluidics), Flow Cytometry, Life Science Research Tools, Microfluidics, Microfluidics And Mem's, Targets And Assays
Category(s): Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microfluidics And Mems, Platforms > Diagnostic Platform Technologies
2021-118 RAPID RESPONSE MICROFLUIDIC CHIP FOR SCREENING THROMBOTIC RISK FROM S-SPIKE PROTEIN IN THE CONTEXT OF SARS-COV-2
SUMMARY: UCLA researchers in the Department of Medicine and Bioengineering have developed a novel microfluidic approach to study SARS-CoV-2 infection entry into blood cells of COVID-19 patients as a research tool to better understand the mechanisms that lead to blood clot formation. BACKGROUND: The World Health Organization estimates that there are...
Published: 9/5/2023   |   Inventor(s): Tzung Hsiai, Angela Lai, Sandro Satta
Keywords(s):  
Category(s): Life Science Research Tools, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Microfluidics And Mems, Platforms > Diagnostic Platform Technologies
2020-908 LASER ACTUATED SUPERCRITICAL INJECTOR (LASI)
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering developed a platform that applies high-speed fluidic jet injection of biomolecules into biological samples with the use of laser actuated supercritical injector (LASI). Background: Intracellular delivery of various biomolecules has been of great importance in biomedical...
Published: 7/19/2023   |   Inventor(s): Pei Yu Chiou
Keywords(s):  
Category(s): Life Science Research Tools > Microfluidics And Mems, Platforms > Drug Delivery, Optics & Photonics, Materials > Nanotechnology
2020-887 A Programmable Epidermal Microfluidic Valving System for Wearable Biofluid Management and Contextual Biomarker Analysis
SUMMARYResearchers in the UCLA Electrical and Computer Engineering Department have devised a programmable epidermal microfluid valving system for high frequency, real-time biofluid sampling, routing, and compartmentalization in wearable bioanalytical platforms.BACKGROUNDWearable biomarker sensing technologies allow for the frequent, longitudinal, and...
Published: 7/19/2023   |   Inventor(s): Sam Emaminejad, Haisong Lin, Jiawei Tan
Keywords(s):  
Category(s): Electrical > Electronics & Semiconductors, Electrical > Sensors, Life Science Research Tools > Microfluidics And Mems, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies
2019-879 An Electronically-Controlled Digital Ferrofluidic Architecture for Scalable and Addressable Bioanalytical Operations
SUMMARYUCLA researchers in the Department of Electrical and Computer Engineering have developed a contactless digital ferrofluidic approach for small-volume droplet generation, manipulation and transport. BACKGROUND Automated microfluidic technologies can perform autonomous, accurate, and consistent fluidic operations. Current automated systems have...
Published: 7/19/2023   |   Inventor(s): Sam Emaminejad, Dino Di Carlo
Keywords(s):  
Category(s): Materials > Nanotechnology, Life Science Research Tools > Microfluidics And Mems, Materials > Fabrication Technologies, Platforms > Diagnostic Platform Technologies, Platforms > Drug Delivery > Nanoparticles, Chemical > Industrial & Bulk Chemicals
Nanoemulsion Technologies
Mason Group Website: http://www.chem.ucla.edu/dept/Faculty/Mason/BACKGROUNDNanoemulsions are oil-in-water (or vice versa) suspensions of nanoscale droplets that range in size from 15 to 100 nm and have a variety of applications including drug delivery, agriculture, personal care and food products. Nanoemulsions have many advantages over traditional...
Published: 7/19/2023   |   Inventor(s): Thomas Mason
Keywords(s):  
Category(s): Chemical > Instrumentation & Analysis, Chemical, Chemical > Emulsions, Chemical > Synthesis, Life Science Research Tools > Microfluidics And Mems, Platforms > Diagnostic Platform Technologies, Platforms > Drug Delivery, Platforms > Drug Delivery > Nanoparticles, Chemical > Chemical Processing & Manufacturing, Materials > Nanotechnology
2011-819 No-Assembly Devices for Microfluidics Inside a Cavity
Summary UCLA researchers have developed a method to fabricate electrowetting microfluidic devices without assembly of their subcomponents. Background Current microfluidic devices having a cavity configuration with multiple electrodes must have their components separately fabricated and subsequently assembled (e.g., bonded, clamped) in order to form...
Published: 7/19/2023   |   Inventor(s):  
Keywords(s):  
Category(s): Life Science Research Tools > Microfluidics And Mems
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