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Search Results - subhra+mohapatra
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Ultrafast UV Laser-Based Virus Inactivation
Advantages Inactivates viruses within seconds, offering much faster performance than standard UV systems. Uses low-power pulsed UV light that produces no ozone or harmful byproducts. Works for both air and surface disinfection through direct and indirect exposure. Provides broad antiviral coverage, effective against coronaviruses and respiratory...
Published: 10/21/2025
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Inventor(s):
Dmitri Voronin
,
Shyam Mohapatra
,
Subhra Mohapatra
,
Sharad Ambardar
,
Mark Howell
,
Karthick Mayilsamy
Keywords(s):
Medical Devices
,
Optical, Laser, Fiberoptic, Spectroscopy
Category(s):
Technology Classifications > Electronics > Electronics Laser
SCOPE: A Brain-Targeted HDHA-Cannabidiol Therapeutic for Resistant Glioblastoma
Advantages Amplified Impact: SCOPE enhances the efficacy of CBD and synergizes with TMZ Lower Dosage, Higher Efficacy: Combination therapy reduces the required CBD/TMZ dose while maintaining strong anti-tumor effects. Enhanced Brain Delivery: enables intranasal administration with significantly higher brain accumulation than oral or intravenous...
Published: 10/20/2025
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Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
Keywords(s):
Cancer Treatment
Category(s):
Technology Classifications > Cancer
,
Technology Classifications > Medical > Oncology
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Biotechnology
A Microfluidic-coupled in vitro Model of the Blood-Brain Barrier (BBB)
Advantages Real-time trans endothelial electrical resistance (TEER) monitoring: embedded Ag/AgCl electrodes enables high-resolution impedance spectroscopy, outperforming conventional models Physiologically relevant tri-culture design: microfluidic flow mimics in vivo BBB hemodynamics with spatially separated HUVECs, astrocytes, and pericytes Enhanced...
Published: 6/5/2025
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Inventor(s):
Shyam Mohapatra
,
Subhra Mohapatra
,
Tao Wang
,
Taylor Martinez
Keywords(s):
Category(s):
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Cell & Tissue Engineering
,
Technology Classifications
,
Technology Classifications > Research Tools/Copyright
,
Technology Classifications > Medical > Neuroscience
Novel Combination Treatment for Glioblastoma
Advantages: Temozolomide (TMZ), Cannabidiol (CBD), and CCR6/CCL20 inhibitors work together to overcome Glioblastoma resistance and enhance efficacy Targeted CCL20/CCR6 inhibition blocks survival pathways in glioblastoma, reducing resistance and relapse while improving outcomes Enhances CD8+ T cells and rewires immunity, offering powerful, lasting...
Published: 4/30/2025
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Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
,
Ryan Green
,
Karthick Mayilsamy
Keywords(s):
Cancer Treatment
,
Pharmaceuticals
Category(s):
Technology Classifications > Chemistry
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical
A Method of Delivering Genes and Drugs to the Posterior Eye
Advantages: Non-invasive administration of PAMAM Dendrimer-based eye drop formulation eliminates risks associated with needle-based procedures and reduces cost Hyaluronic acid (HA) on the Dendrimer surface targets overexpressed CD44 receptors on retinal cells, potentially leading to higher bioavailability in the posterior eye Encapsulation of poorly...
Published: 3/10/2025
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Inventor(s):
Shyam Mohapatra
,
Subhra Mohapatra
,
Eleni Markoutsa
Keywords(s):
Category(s):
Technology Classifications > Medical > Ophthalmology
Combination Therapy to Treat Viral Acute Respiratory Distress Syndrome (ARDS)
Advantages: PG’s anti-inflammatory effects mitigate viral inflammation of COVID-19. Intranasally administered mesenchymal stem cells (MSCs) create an anti-inflammatory microenvironment and can enhance neuro-regenerative effects. Targets viral transmission and neuronal damage to reduce virus-induced neuronal damage, and mortality, and...
Published: 7/15/2024
|
Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
,
Mahasweta Das
,
Andrew McGill
,
Karthick Mayilsamy
Keywords(s):
Covid-19
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
Withaferin A and Immune Checkpoint Blocker Therapy for The Treatment of Non-Small Cell Lung Cancer
Advantages: Improved Immunotherapy Outcomes: Significantly enhances the effectiveness of immunotherapy for NSCLC, improving treatment success rates. Personalized Cancer Care: Enables tailored treatments based on individual tumor characteristics, leading to more precise and efficient therapies. Enhanced Safety Profile: Promises a well-tolerated...
Published: 10/14/2025
|
Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
,
Roukiah Khalil
Keywords(s):
Cancer Treatment Lung Cancer
Category(s):
Technology Classifications > Cancer > Cancer Treatment Lung Cancer
Exploring Choroid Plexus Senescence as a Potential Link Between COVID-19 and Alzheimer's Disease
Advantages: Advances viral neurology research by studying SARS-CoV-2's impact on the aging brain's choroid plexus. Identifies potential biomarkers for neurodegenerative diseases through cellular senescence and SASP factor analysis. Informs public health strategies regarding COVID-19-related neurological complications and preventive...
Published: 10/14/2025
|
Inventor(s):
Eleni Markoutsa
,
Shyam Mohapatra
,
Subhra Mohapatra
Keywords(s):
Infectious Diseases
,
Neurodegenerative Diseases
,
Therapeutics
Category(s):
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Neuroscience
,
Technology Classifications > Medical > Therapeutics
Method of Treating Long-COVID Induced Neurologic Diseases
Advantages: Method of preventing AD onset following severe COVID RNA Nano-carrier system carrying dual (brain and CNS)-targeted dendriplexes to target the brain and CNS Summary: COVID-19 is primarily a respiratory disease; however, neurological symptoms are also reported in a subpopulation of infected COVID-19 individuals. Complementary...
Published: 10/14/2025
|
Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
,
Paula Bickford
,
Laura Blair
,
Bala Chandran
,
Karthick Mayilsamy
,
Ryan Green
Keywords(s):
Category(s):
Technology Classifications > Medical > Neuroscience
RAiD2: Robotics and AI for Onsite Detection and Disinfection
Advantages: Precise and non-contact disinfection User-friendly and portable autonomous operation Robotic and AI-augmented advanced control Business Summary: The RAiD2 platform combats biological threats, particularly during the COVID-19 pandemic. The platform integrates multiplexed nucleic acid-based biosensing for onsite detection, corona...
Published: 9/4/2024
|
Inventor(s):
Ying Zhong
,
Subhra Mohapatra
,
Shyam Mohapatra
,
Ehsan Sheybani
,
Tansel Yucelen
Keywords(s):
Artificial Intelligence
,
Electronics
,
Infectious Diseases Treatment
,
Medical Devices
,
Robotics
,
Sensors
Category(s):
Technology Classifications > Data/AI > D/AI Imaging
,
Technology Classifications > Electronics > Electronics Sensors
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Engineering > Sensors
,
Technology Classifications > Medical > Biomaterials
,
Technology Classifications > Medical
,
Technology Classifications > Medical > Medical Sensors
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