Search Results - john+adams

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Antimalarial peptides
­Competitive Advantages Potential treatment for malaria Could be effective against drug resistant strain Dd2 The resulting compounds showed no significant cytotoxicity Summary Malaria, caused by the parasite Plasmodium falciparum, continues to threaten much of the world population and there is a pressing need for expanding treatment options....
Published: 9/3/2024   |   Inventor(s): Bill Baker, Joe Bracegirdle, James Rocca, John Adams, Nerida Wilson, Debora Casandra, Xingmin Sun, Anne-Claire Limon
Keywords(s): Infectious Diseases Treatment, Peptides, Therapeutics
Category(s): Technology Classifications > Chemistry, Technology Classifications > Medical > Infectious Diseases
Sporozoite Cryopreservation Compositions and Methods
Competitive Advantages Retains significantly high viablility Effective for plasmodium research Application in whole-parasite vaccine Key role in liver stage research Summary We have developed a novel method to allow the harvested sporozoites to be cryopreserved and thawed effectively. This method will allow the sporozoites to retain a significantly...
Published: 5/31/2023   |   Inventor(s): John Adams, Alison Roth
Keywords(s):  
Category(s): Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical
Friomaramide, a Novel Hexapeptide, Inhibits Liver Stage Plasmodium Falciparum
Competitive Advantages A novel molecule that can inhibit P. falciparum in malaria Bypasses drug resistance Limited toxicity towards human cells Summary USF researchers have developed a novel modified hexapeptide called friomaramide. It inhibits the growth of P. falciparum to a similar degree as the antimalarial drug primaquine, with the added...
Published: 6/13/2023   |   Inventor(s): Bill Baker, Nerida Wilson, John Adams, Alison Roth, Matthew Knestrick
Keywords(s):  
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical