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Search Results - shyam+mohapatra
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Combination Therapy to Treat Viral Acute Respiratory Distress Syndrome (ARDS)
Advantages: PG’s anti-inflammatory effects mitigate viral inflammation of COVID-19. Intranasally administered mesenchymal stem cells (MSCs) create an anti-inflammatory microenvironment and can enhance neuro-regenerative effects. Targets viral transmission and neuronal damage to reduce virus-induced neuronal damage, and mortality, and...
Published: 7/15/2024
|
Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
,
Mahasweta Das
,
Andrew McGill
,
Karthick Mayilsamy
Keywords(s):
Covid-19
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Respiratory
Treating Kidney Disorders via Targeted Nanoparticles
Advantages: Collagen IV targeted nanoparticles for drug delivery to kidney glomeruli to treat lupus nephritis and other kidney disorders. Therapeutic efficiency: The nanoparticles loaded with prednisone effectively treated lupus nephritis in mice. Reduced systemic toxicity. Summary: Our inventors developed a novel nanoparticle drug delivery...
Published: 5/28/2024
|
Inventor(s):
Shyam Mohapatra
,
Ruisheng Liu
Keywords(s):
Nanotechnology
,
Renal / Kidney
Category(s):
Technology Classifications > Electronics > Nanotechnology
,
Technology Classifications > Medical > Therapeutics
Withaferin A and Immune Checkpoint Blocker Therapy for The Treatment of Non-Small Cell Lung Cancer
Advantages: Improved Immunotherapy Outcomes: Significantly enhances the effectiveness of immunotherapy for NSCLC, improving treatment success rates. Personalized Cancer Care: Enables tailored treatments based on individual tumor characteristics, leading to more precise and efficient therapies. Enhanced Safety Profile: Promises a well-tolerated...
Published: 11/14/2023
|
Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
,
Roukiah Khalil
Keywords(s):
Cancer Treatment Lung Cancer
Category(s):
Technology Classifications > Cancer > Cancer Treatment Lung Cancer
A Liposomal Nanoformulation Encapsulating Linolenic Acid and Acetate Inhibits SARS-CoV-2 Infection
Advantages: This research offers the potential to combat SARS-CoV-2 and respiratory viruses such as RSV and other coronaviruses. The research addresses various issues of the disease by targeting both the host and viral factors, including reduction in viral replication dampening the excessive immune response. The development of nanoformulations...
Published: 12/20/2023
|
Inventor(s):
Andrew McGill
,
Subhra Mohapatra
,
Shyam Mohapatra
,
Eleni Markoutsa
,
Karthick Mayilsamy
Keywords(s):
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Respiratory
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Medical Nanotechnology
Exploring Choroid Plexus Senescence as a Potential Link Between COVID-19 and Alzheimer's Disease
Advantages: Advances viral neurology research by studying SARS-CoV-2's impact on the aging brain's choroid plexus. Identifies potential biomarkers for neurodegenerative diseases through cellular senescence and SASP factor analysis. Informs public health strategies regarding COVID-19-related neurological complications and preventive...
Published: 5/9/2024
|
Inventor(s):
Eleni Markoutsa
,
Shyam Mohapatra
,
Subhra Mohapatra
Keywords(s):
Infectious Diseases
,
Neurodegenerative Diseases
,
Therapeutics
Category(s):
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Neuroscience
,
Technology Classifications > Medical > Therapeutics
Method of Treating Long-COVID Induced Neurologic Diseases
Advantages: Method of preventing AD onset following severe COVID RNA Nano-carrier system carrying dual (brain and CNS)-targeted dendriplexes to target the brain and CNS Summary: COVID-19 is primarily a respiratory disease; however, neurological symptoms are also reported in a subpopulation of infected COVID-19 individuals. Complementary...
Published: 4/26/2024
|
Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
,
Paula Bickford
,
Laura Blair
,
Bala Chandran
,
Karthick Mayilsamy
,
Ryan Green
Keywords(s):
Category(s):
Technology Classifications > Medical > Neuroscience
RAiD2: Robotics and AI for Onsite Detection and Disinfection
Advantages: Precise and non-contact disinfection User-friendly and portable autonomous operation Robotic and AI-augmented advanced control Business Summary: The RAiD2 platform combats biological threats, particularly during the COVID-19 pandemic. The platform integrates multiplexed nucleic acid-based biosensing for onsite detection, corona...
Published: 9/4/2024
|
Inventor(s):
Ying Zhong
,
Subhra Mohapatra
,
Shyam Mohapatra
,
Ehsan Sheybani
,
Tansel Yucelen
Keywords(s):
Artificial Intelligence
,
Electronics
,
Infectious Diseases Treatment
,
Medical Devices
,
Robotics
,
Sensors
Category(s):
Technology Classifications > Data/AI > D/AI Imaging
,
Technology Classifications > Electronics > Electronics Sensors
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Engineering > Sensors
,
Technology Classifications > Medical > Biomaterials
,
Technology Classifications > Medical
,
Technology Classifications > Medical > Medical Sensors
Natriuretic Peptide Receptor as a Biomarker for Cancer
Our inventors have come up with a diagnostic method for differentiating low grade cancers from high grade cancers by correlating the level of NPRA to favorable or unfavorable prognosis. With this method, clinical detection of a number of malignancies, amongst included are various cancers, can be diagnosed and treated earlier improving the chances for...
Published: 8/27/2023
|
Inventor(s):
Shyam Mohapatra
,
Subhra Mohapatra
Keywords(s):
Cancer Diagnostics
Category(s):
Technology Classifications > Cancer > Cancer Diagnostics
,
Technology Classifications > Cancer
Mithramycin A in Combination with Cancer Immunotherapy
Competitive Advantages Reformulated combination therapeutic allows for shorter clinical pathway Targets cancer stem cells and their ability to escape the immune system More effective at inhibiting tumor growth than either treatment alone Summary Our researchers have formulated a method to target cancer stem cells (CSCs) using Mithramycin...
Published: 9/25/2023
|
Inventor(s):
Subhra Mohapatra
,
Shyam Mohapatra
,
Rinku Dutta
,
Quarni Waise
Keywords(s):
Cancer Treatment
,
Medical Therapeutics Cell Therapy
Category(s):
Technology Classifications > Cancer
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical
Drug Delivery Device for Ovarian Cancer
Competitive Advantages Protects healthy cells from exposure to toxic drugs Targeted drug delivery effectively supplies safe dosage to site of disease Improves post-treatment prognosis and may prevent cancer recurrence Summary Our researchers have developed a device with the ability to deliver precise and effective dosage quantities...
Published: 8/27/2023
|
Inventor(s):
Shyam Mohapatra
,
Susana Lai-Yuen
,
Arun Kumar
Keywords(s):
Category(s):
Technology Classifications > Cancer
,
Technology Classifications > Medical
,
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Medical Devices
,
Technology Classifications > Medical > Womens Health
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