Search Results - antiviral+therapeutics

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Antiviral Properties of Deep-Sea Coral Metabolites
Advantages: A novel compound for developing new antiviral drugs extracted from the Irish deep-sea soft coral Anthoteibinene B exhibits significant antiviral activity against Respiratory Syncytial Virus (RSV) without cytotoxic effects N,N-dimethylaminoethyl substituents further enhance antiviral properties by improving solubility, bioavailability,...
Published: 11/7/2024   |   Inventor(s): Bill Baker, Stine Olsen, Sam Afoullouss, Kim Teng, Michael Teng, Louise Allcock, Mark Johnson
Keywords(s): Antiviral Therapeutics
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Chemistry, Technology Classifications > Medical > Therapeutics
New natural product scaffolds with activity against respiratory syncytial virus from the Antarctic Sponge Suberites sp.
­Advantages: This research introduces a novel class of compounds, including neosuberitenone, which demonstrates selectivity against respiratory syncytial virus (RSV). The research's focus on small molecules derived from a natural source, the Antarctic sponge Suberites sp., hints at the potential for cost-effective treatments. The identified...
Published: 11/7/2024   |   Inventor(s): Bill Baker, Joe Bracegirdle, Stine Olsen, Michael Teng, Kim Tran, Charles Amsler, James McClintock
Keywords(s): Antiviral Therapeutics, Infectious Diseases Treatment, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Infectious Diseases
Preventing Alu SINEs-Mediated Immune Pathologies
Advantages: Discovered a novel mechanism of anti-viral defense during pregnancy Developed a novel method to predict susceptibility for viral infections during pregnancy Developed a novel method to treat interferon-related pathologies with maladaptive immune responses Business Summary: Viral infections during pregnancy cause devastating effects...
Published: 8/21/2024   |   Inventor(s): Hana Totary-Jain
Keywords(s): Antiviral Therapeutics, Therapeutics, Women’s Health
Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Womens Health, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Biotechnology
Peptidomimetic-Based Antibody Surrogate for HER2
­Advantages: High affinity for HER2 and inhibits downstream signaling Potent anti-tumor effects Small molecular weight Resistant to proteolysis Summary: Current HER2-targeted therapies, including monoclonal antibody trastuzumab, are hindered by high cost of production, large molecular weight, and susceptibility to degradation. A novel...
Published: 8/24/2023   |   Inventor(s): Jianfeng Cai, Mengmeng Zheng
Keywords(s): Antibodies, Antiviral Therapeutics, Cancer, Peptides
Category(s): Technology Classifications > Cancer > Cancer Treatment Breast Cancer