Inteum Company
Links
seedsprint
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - hana+totary-jain
10
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Short Nuclear Repeat Element (SINE) RNA of Imprinted MicroRNA Clusters Mediate the Intrinsic, Type III Interferon-driven Viral Resistance of Hemochorial Placentas
Advantages: Enhanced understanding of improved prenatal protection: Discovered a novel mechanism by which SINE RNA mediate intrinsic antiviral resistance in the placenta Opens the door to therapeutic intervention Summary: Addressing a fundamental challenge in prenatal health, this research investigates how the placenta at the maternal-fetal...
Published: 9/26/2023
|
Inventor(s):
Hana Totary-Jain
Keywords(s):
Medical Therapeutics Gene Therapy
,
Women’s Health
Category(s):
Technology Classifications > Medical > Biomedical Engineering
,
Technology Classifications > Medical > Womens Health
Method for measuring Alu RNA
Advantages: Accurate Quantification: The competitive RT-PCR method allows for precise measurement of the ratio between fl-Alu and sc-Alu transcripts. Sensitivity: The assay can detect even low levels of Alu RNA expression. Versatility: The primer set used in the assay can amplify the most abundant form of Alu, making it applicable for various samples...
Published: 11/13/2024
|
Inventor(s):
Hana Totary-Jain
Keywords(s):
Autoimmune Diseases
,
Cancer
,
Genetics
,
Infectious Diseases
,
Neurodegenerative Diseases
Category(s):
Technology Classifications > Medical > Medical Diagnostics
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Cancer
LIN28B as Biomarker for Infantile Hemangioma
Advantages: Mechanism of infantile hemangioma (IH) involution mediated by propranolol treatment Novel Diagnostic Cancer Biomarker for infantile hemangioma: LIN28B Therapeutic applications beyond infantile hemangiomas, for propranolol sensitive tumors Business Summary: The β-adrenergic receptor antagonist propranolol has been shown to have...
Published: 6/11/2024
|
Inventor(s):
Hana Totary-Jain
Keywords(s):
Therapeutics
Category(s):
Technology Classifications > Medical > Medical Nanotechnology
,
Technology Classifications > Medical > Therapeutics
Method to visualize Alu RNA in tissue
Advantages: Spatial localization Compatibility with Fixed Tissues Multiplexing Capabilities Business Summary: Retrotransposons (RTs) are the most abundant class of the transposable elements that comprise approximately 45% of the human genomic sequence, of which Alu repeats (Alus) are the most abundant and comprise 11% of the genomic sequence....
Published: 5/20/2024
|
Inventor(s):
Hana Totary-Jain
Keywords(s):
Genetics
,
Medical Devices
,
Research Tools
Category(s):
Technology Classifications > Medical
,
Technology Classifications > Medical > Medical Diagnostics
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Biotechnology
Targeting Alu RNA to treat atherosclerotic cardiovascular disease
Advantages Human Lungs & coronary arteries from COVID-19 patients showed increased expression of Alu RNA Alu RNA induces non-resolving inflammation in atherosclerosis Antisense Oligos targeting Alu RNA can reduce inflammation Summary Atherosclerotic cardiovascular diseases continue to be the leading cause of death worldwide. Viral infections,...
Published: 4/26/2024
|
Inventor(s):
Hana Totary-Jain
Keywords(s):
Cardiovascular Diseases
,
Inflammation
Category(s):
Technology Classifications > Medical > Therapeutics
Preventing Alu SINEs-Mediated Immune Pathologies
Advantages: Discovered a novel mechanism of anti-viral defense during pregnancy Developed a novel method to predict susceptibility for viral infections during pregnancy Developed a novel method to treat interferon-related pathologies with maladaptive immune responses Business Summary: Viral infections during pregnancy cause devastating effects...
Published: 8/21/2024
|
Inventor(s):
Hana Totary-Jain
Keywords(s):
Antiviral Therapeutics
,
Therapeutics
,
Women’s Health
Category(s):
Technology Classifications > Medical
,
Technology Classifications > Medical > Medical Diagnostics
,
Technology Classifications > Medical > Womens Health
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Biotechnology
Smooth Muscle Specific Inhibition for Anti-Restenotic Therapy
Competitive Advantages Prevents restenosis Reduces inflammation Reduces hypercoagulability Preserves endothelial cell function Summary USF researchers have developed the first miRNA-based strategy to selectively inhibit VSMC proliferation and migration for the prevention of restenosis, without concurrently inhibiting reendothelialization...
Published: 8/26/2023
|
Inventor(s):
Andrew Marks
,
Steven Marx
,
Hana Totary-Jain
Keywords(s):
Category(s):
Technology Classifications > Medical
,
Technology Classifications > Medical > Therapeutics
Cistron Mediated Intrinsic Interferon and Antiviral Response in Human Placenta
Competitive Advantages Predict susceptibility for infection or severity of infection in pregnant women Reduced viral infections during pregnancy Protection of both maternal and fetal health against infections Uses the placenta at the maternal-fetal interfaces for antiviral response Summary Viral infections during pregnancy have often caused...
Published: 8/21/2024
|
Inventor(s):
Hana Totary-Jain
Keywords(s):
Infectious Diseases Treatment
,
Women’s Health
Category(s):
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Womens Health
Cell-Selective Gene Editing
Competitive Advantages: Reduced toxicity High flexibility Ability to edit multiple genes and target multiple cell types Summary: Modified mRNA-based therapeutics hold great promise for numerous untreatable diseases. The potential advantages of modified mRNA biomolecules include reduced toxicity, decreased activation of the innate...
Published: 5/20/2024
|
Inventor(s):
Hana Totary-Jain
Keywords(s):
Category(s):
Technology Classifications > Medical
,
Technology Classifications > Medical > Therapeutics
MicroRNA-based Therapy for Infantile Hemangioma (IH)
Competitive Advantages Gene Editing Therapy to inhibit overexpressed C19MC promoter region commonly found in IH Reduces cell proliferation & decreases cell migration Ameliorates potential side effects A non-invasive surgical method Summary Infantile hemangiomas (IHs) are common benign vascular tumors in childhood. Until...
Published: 5/20/2024
|
Inventor(s):
Hana Totary-Jain
Keywords(s):
Category(s):
Technology Classifications > Medical > Cell & Tissue Engineering
,
Technology Classifications > Medical