Search Results - charles+amsler

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New natural product scaffolds with activity against respiratory syncytial virus from the Antarctic Sponge Suberites sp.
­Advantages: This research introduces a novel class of compounds, including neosuberitenone, which demonstrates selectivity against respiratory syncytial virus (RSV). The research's focus on small molecules derived from a natural source, the Antarctic sponge Suberites sp., hints at the potential for cost-effective treatments. The identified...
Published: 11/7/2024   |   Inventor(s): Bill Baker, Joe Bracegirdle, Stine Olsen, Michael Teng, Kim Tran, Charles Amsler, James McClintock
Keywords(s): Antiviral Therapeutics, Infectious Diseases Treatment, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Infectious Diseases
Antibiofilm terpenoids derived from the Antarctic sponge Dendrilla membranosa
Competitive Advantages New natural products and derivatives that are effective at eradicating Methicillin-resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii biofilms Not cytotoxic to mammalian cells Summary Biofilms are formed by all bacterial species. In the context of human disease, biofilms are the driving force behind many...
Published: 11/7/2024   |   Inventor(s): Bill Baker, Lindsey Shaw, Andrew Shilling, Alexandre Bory, Jessie Adams, Charles Amsler, James McClintock
Keywords(s):  
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical
MRSA Biofilm Inhibition
Competitive Advantages A novel antibiofilm agent Treats and prevents biofilm growth Inhibits drug resistant bacterial infections including MRSA Low toxicity towards mammalian cells Summary USF researchers have developed a method of treating or preventing drug resistant bacterial infections including methicillin-resistant biofilm infections...
Published: 11/25/2024   |   Inventor(s): Bill Baker, Lindsey Shaw, James McClintock, Charles Amsler, Jacqueline Fries, Christopher Witowski, Renee Fleeman
Keywords(s):  
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical