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Search Results - stine+olsen
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Antimicrobial Terpenes From a Deep-Sea Irish Coral
Advantages: A novel structural diversity (anthoteibinenes A-Q) offers bioactive scaffolds, absent in standard combinatorial chemistry libraries Anthoteibinenes I and J have demonstrated activity against multiple Candida strains, indicating possible antibacterial efficacy Selective bioassay- and NMR-guided isolation provides a more targeted approach...
Published: 2/21/2025
|
Inventor(s):
Bill Baker
,
Stine Olsen
,
Mark Johnson
,
Louise Allcock
,
Sam Afoullouss
,
Ezequiel Rosa
,
Ryan Young
Keywords(s):
Category(s):
Technology Classifications > Chemistry
,
Technology Classifications > Medical
,
Technology Classifications > Medical > Pharmaceuticals
Antiviral Properties of Deep-Sea Coral Metabolites
Advantages: A novel compound for developing new antiviral drugs extracted from the Irish deep-sea soft coral Anthoteibinene B exhibits significant antiviral activity against Respiratory Syncytial Virus (RSV) without cytotoxic effects N,N-dimethylaminoethyl substituents further enhance antiviral properties by improving solubility, bioavailability,...
Published: 11/7/2024
|
Inventor(s):
Bill Baker
,
Stine Olsen
,
Sam Afoullouss
,
Kim Teng
,
Michael Teng
,
Louise Allcock
,
Mark Johnson
Keywords(s):
Antiviral Therapeutics
Category(s):
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Chemistry
,
Technology Classifications > Medical > Therapeutics
New natural product scaffolds with activity against respiratory syncytial virus
Advantages: This research introduces a novel class of compounds, including neosuberitenone, which demonstrates selectivity against respiratory syncytial virus (RSV). The research's focus on small molecules derived from a natural source, the Antarctic sponge Suberites sp., hints at the potential for cost-effective treatments. The identified...
Published: 3/27/2025
|
Inventor(s):
Bill Baker
,
Joe Bracegirdle
,
Stine Olsen
,
Michael Teng
,
Kim Tran
,
Charles Amsler
,
James McClintock
Keywords(s):
Antiviral Therapeutics
,
Infectious Diseases Treatment
,
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Respiratory
,
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Infectious Diseases