Search Results - ji+qiu

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Antimicrobial Antibody Panels for Lung Cancer Detection
the second most common cancer in both men and women and the leading cause of cancer death in the US. Although there are risk factors for lung cancer, such as smoking, there are many cases where the patient never smoked. Because of this, there is growing interest in investigating the lung microbiota and how that may promote or prevent disease. Yearly...
Published: 8/2/2023   |   Inventor(s): Mahasish Shome, Ji Qiu, Yunro Chung, Joshua LaBaer
Keywords(s):  
Category(s): Cancer, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
Autoantibodies for Identification of False Positives of Disease and Uses Thereof
Autoantibodies are an excellent biomarker for both autoimmune disease and cancer, however, some autoantibodies, called common autoantibodies, have been found to occur frequently in healthy individuals. The presence of these common autoantibodies can impede the search for disease-linked autoantibodies or lead to false positives. The identification of...
Published: 3/30/2023   |   Inventor(s): Mahasish Shome, Yunro Chung, Ramani Chavan, Jin Park, Ji Qiu, Joshua LaBaer
Keywords(s):  
Category(s): Applied Technologies, Cancer, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors
Novel Antibodies for Detecting Gastric Cancer or Gastric Intestinal Metaplasia
Gastric cancer (GC) is a major public health problem in many countries, with more than 1 million new cases, worldwide, in 2020, contributing to almost 800,000 deaths. And new research suggests that GC may be on the rise in the US, particularly among younger adults. Early detection of GC often allows for greater therapeutic options, however, because...
Published: 3/7/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Lusheng Song, Yunro Chung
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
Type 1 Diabetes Biomarkers
Type 1 Diabetes (T1D) is one of the most common juvenile autoimmune diseases and is characterized by progressive destruction of pancreatic ß-cells. By the time of T1D diagnosis, around 70-90% of pancreatic ß-cells are already dead. T1D patients face many potential health complications and co-morbidities which lead to both personal and societal...
Published: 2/23/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Xiaofang Bian, Desmond Schatz, Clive Wasserfall, Mark Atkinson
Keywords(s): Autoantibody, Bioanalysis, biomarker, Detection, Diabetes, Diagnostics, Early Detection, ELISA, Screening
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Biomarkers for Diagnosis of Lung Cancer
In 2021, 134,592 people died from lung cancer, or 22% of all cancer deaths. Lung cancer is the leading cause of cancer death overall and among both men and women. While the increased use of CT screening for lung cancer has resulted in a reduction in lung cancer mortality, it has also resulted in an increased detection of benign pulmonary nodules. Patients...
Published: 10/29/2024   |   Inventor(s): Joshua LaBaer, Ji Qiu, Jie Wang, Garrick Wallstrom, Jin Park, William Rom, Harvey Pass
Keywords(s): Autoantibody, Biomarker discovery
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
Novel Biomarkers for Detecting Epstein-Barr Virus-Associated Gastric Cancer
Gastric cancer (GC) is a major health public problem in many countries, with more than 1 million new cases, worldwide, in 2018, contributing to almost 800,000 deaths. And new research suggests that GC may be on the rise in the US, particularly among younger adults. Early detection of GC often allows for greater therapeutic options, however, because...
Published: 2/23/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Lusheng Song, Yunro Chung
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Cancer Therapeutics, Diagnostic Assays/Devices, Proteomic Assays/Reagents/Tools, Life Science (All LS Techs), Vaccines/Antimicrobials
Novel Antibodies for Detecting Gastric Cancer
Gastric cancer (GC) is a major public health problem in many countries, with more than 1 million new cases, worldwide, in 2018, contributing to almost 800,000 deaths. And new research suggests that GC may be on the rise in the US, particularly among younger adults. Early detection of GC often allows for greater therapeutic options, however, because...
Published: 2/23/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Lusheng Song, Yunro Chung
Keywords(s): Antibodies, Antibody Therapeutics, Bioanalysis, Bioassay, Cancer, Diagnostics, Immunosignature, Infectious Disease, Protein Assays
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Medical Diagnostics/Sensors
Autoantibody Biomarkers for Crohn’s Disease
Crohn’s disease (CD), is an inflammatory bowel disease that affects about 3 out of 1,000 people in the U.S. It is currently not known what causes CD, but hereditary, environmental factors and a dysregulated immune system are thought to play a role. Diagnosis of CD is difficult and often involves expensive imaging and invasive biopsies. Current...
Published: 10/19/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Haoyu Wang, Shabana Pasha, Jonathan Leighton
Keywords(s): Antibodies, Autoantibody, biomarker, Biomarker discovery, Diagnostics
Category(s): Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
HT Fusion Tag Detection
Because of their unique recombinant properties, fusion proteins are of intense interest in many biotechnology applications. Current methods to specifically detect expression of fusion proteins exist; but, they are either unsuitable for high throughput (HTP) processes, in the case of western blots, or are non-qualitative, in the case of ELISAs. Assessment...
Published: 2/23/2023   |   Inventor(s): Justin Saul, Ji Qiu, Joshua LaBaer, Mitch Magee, John Chaput, Sujay Sau
Keywords(s): Fluorescence, Protein Assays
Category(s): Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Generation of Recombinant Affinity Reagents
Creating protein affinity reagents on a proteome-wide scale is one of the greatest challenges of modern medicine. High quality reagents to capture proteins are necessary for elucidating protein function, developing new molecular diagnostics and even therapeutics. Recent advances in protein discovery will necessitate the need for affinity reagents to...
Published: 5/6/2023   |   Inventor(s): Joshua LaBaer, Jie Wang, Ji Qiu, Kevin Gorman, Brian Kay
Keywords(s): Affinity Reagent, Phage display, Protein array
Category(s): Proteomic Assays/Reagents/Tools, Life Science (All LS Techs), Genomic Assays/Reagents/Tools
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