Search Results - shaopeng+wang

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Plasmonic Cell Force Microscopy
Cellular force is important in activities including migration, proliferation and differentiation, which are mediated by interactions between the cell and the ECM. Monitoring these interactions helps to understand how and when mechanical cues play a role in cellular events and underlying mechanisms. However, there are limitations in spatial and temporal...
Published: 6/24/2025   |   Inventor(s): Shaopeng Wang, Xinyu Zhou, Ryan Porter
Keywords(s):  
Category(s): Imaging, Life Science (All LS Techs), Medical Imaging
One-Step Label-Free Molecular Interaction Kinetic Measurement
Molecular interactions are integral to virtually all biological processes including cell signaling, enzyme activity, protein functionality, and disease development. Understanding the kinetics of these interactions is crucial for providing detailed quantitative and mechanistic insights, at the molecular level, which are essential for advancements in...
Published: 6/10/2025   |   Inventor(s): Shaopeng Wang, Xiaoyan Zhou
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Imaging, Life Science (All LS Techs)
VITRUALGENOME, A VIRTUAL REALITY IMMERSIVE SYSTEM
VAlue proposition A virtual reality immersive system that enables users to visualize, explore, and analyze 3D genomes and their associated biochemical features. Combining VirtualGenome with Tensor-FLAMINGO and 3DVarientVision creates a technology that provides a high-resolution image of the altered 3D structure resulting from a genetic variant, decodes...
Published: 4/9/2025   |   Inventor(s): Jianrong Wang, Andre Popovitch, Hao Wang
Keywords(s):  
Category(s): Biotechnology, Computer Software, Education & Training
HIGH-RESOLUTION RECONSTRUCTION OF SINGLE-CELL 3D CHROMOSOMAL STRUCTURES
VAlue proposition The dynamic 3D spatial structure of chromosomes has variations across cells of different types and between cells of the same type. This structural variation between single cells plays an important role in regulating single-cell specific transcription and epigenetic landscapes. Computationally reconstructing chromosomal 3D structure...
Published: 4/9/2025   |   Inventor(s): Jianrong Wang, Jianliang Qian, Hao Wang
Keywords(s):  
Category(s): Biotechnology, Computer Software
Rapid Tuberculosis and Mycobacteria Phenotypic Drug Susceptibility Testing
Mycobacterium tuberculosis (TB) remains a major global health threat, causing nearly 1.5 million deaths annually, making it the 13th leading cause of death. While TB is preventable and treatable, multidrug-resistant TB worsens the global health crisis, making diagnosis and treatment more complex. An even greater challenge is heteroresistance, where...
Published: 4/8/2025   |   Inventor(s): Shelley Haydel, Shaopeng Wang, Jiapei Jiang, Yannik Haller
Keywords(s):  
Category(s): Artificial Intelligence/Machine Learning, Vaccines/Antimicrobials, Life Science (All LS Techs), Imaging, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices
Affinity Encoded Nano-Oscillator Array
Nanoarray-based assays offer advantages over standard microarray assays such as minimal sample consumption, high efficiency, and enhanced multiplexing capacity. However, despite their potential, they face challenges such as the complexity and high cost of spotting and fabrication, as well as a lack of effective detection schemes. This impedes many practical...
Published: 3/4/2025   |   Inventor(s): Shaopeng Wang, Shuo-Hui Cao
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Cancer, Life Science (All LS Techs), Imaging, Proteomic Assays/Reagents/Tools, Chemical/Biological Sensors
Glycan Binding HTS Platform for Drug Development
Description This technology is an innovative glycan library platform for drug development. This is a DNA-encoded glycan library (DEGL) platform demonstrating higher content and throughput potential. Scientists can utilize this platform to identify and study specific glycan structures through unique DNA barcodes, facilitating drug screening and lead...
Published: 7/15/2025   |   Inventor(s): Peng Wang, Mohammed Kondengadan, Aishwarya Parameswaran, Jing Song, Liuqing Wen, Huajie Zhang
Keywords(s):  
Category(s): Assay, Research Tool
Microfluidic Digital Nanobiosensor for Point-of-Care Detection of NT-proBNP
Heart failure is a serious global burden affecting more than 64 million people worldwide. It has high morbidity and mortality and poor quality of life, making it a major public health priority. N-terminal proBNP (NT-pro-BNP) is a well-established clinical biomarker for monitoring and managing heart failure. Regular and frequent monitoring of patients...
Published: 2/13/2025   |   Inventor(s): Shaopeng Wang, Chao Chen
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Medical Devices
Label-free Single-molecule Immunoassay Technique
Detection and quantification of low-abundance biomarkers is essential to early disease detection, monitoring and treatment. While many techniques, have been developed for measuring single molecules, all require signal amplification, via enzyme amplification, or fluorescence or gold nanoparticle probes, which come with their own unique drawbacks, including...
Published: 2/13/2025   |   Inventor(s): Shaopeng Wang, Xiaoyan Zhou
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Imaging, Life Science (All LS Techs), Medical Diagnostics/Sensors, Medical Devices
Optical Imaging Platform for POC CAR T-Cell Therapy Assessment
Chimeric antigen receptor (CAR) T-cell therapy is a type of immunotherapy which uses altered T-cells to target cancer cells more effectively. As such, it has dramatically changed the treatment landscape for cancer patients. However, it has limitations including cytokine release syndrome (CRS), neurological events (NE), lack of response (which occurs...
Published: 2/13/2025   |   Inventor(s): Shaopeng Wang, Nanxi Yu, Chao Chen, Xinyu Zhou, Januario Castro, Eider Moreno Cortes
Keywords(s):  
Category(s): Medical Diagnostics/Sensors, Medical Devices, Life Science (All LS Techs), Imaging, Cancer, Bioanalytical Assays, Chemistries & Devices
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