Search Results - shaopeng+wang

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Microfluidic Digital Nanobiosensor for Point-of-Care Detection of NT-proBNP
Heart failure is a serious global burden affecting more than 64 million people worldwide. It has high morbidity and mortality and poor quality of life, making it a major public health priority. N-terminal proBNP (NT-pro-BNP) is a well-established clinical biomarker for monitoring and managing heart failure. Regular and frequent monitoring of patients...
Published: 9/3/2024   |   Inventor(s): Shaopeng Wang, Chao Chen
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Medical Devices
Label-free Single-molecule Immunoassay Technique
Detection and quantification of low-abundance biomarkers is essential to early disease detection, monitoring and treatment. While many techniques, have been developed for measuring single molecules, all require signal amplification, via enzyme amplification, or fluorescence or gold nanoparticle probes, which come with their own unique drawbacks, including...
Published: 9/3/2024   |   Inventor(s): Shaopeng Wang, Xiaoyan Zhou
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Imaging, Life Science (All LS Techs), Medical Diagnostics/Sensors, Medical Devices
Optical Imaging Platform for POC CAR T-Cell Therapy Assessment
Chimeric antigen receptor (CAR) T-cell therapy is a type of immunotherapy which uses altered T-cells to target cancer cells more effectively. As such, it has dramatically changed the treatment landscape for cancer patients. However, it has limitations including cytokine release syndrome (CRS), neurological events (NE), lack of response (which occurs...
Published: 8/27/2024   |   Inventor(s): Shaopeng Wang, Nanxi Yu, Chao Chen, Xinyu Zhou, Januario Castro, Eider Moreno Cortes
Keywords(s):  
Category(s): Medical Diagnostics/Sensors, Medical Devices, Life Science (All LS Techs), Imaging, Cancer, Bioanalytical Assays, Chemistries & Devices
Cryogenic Propellant Storage Tank Chill-Down and Filling for Refueling in Microgravity and Reduced Gravity Environments
Uses Spray Cooling with Flow Pulsing to Prevent the Unnecessary Boiling of Cryogenic Propellant Film in Microgravity and Reduced Gravity Environments This storage tank and propellant transfer apparatus conserves valuable cryogenic propellants in reduced gravity and microgravity environments. The extension of human space exploration is NASA’s...
Published: 9/3/2024   |   Inventor(s): Jacob Chung, Jason Hartwig, Hao Wang, Bo-Han Huang, Jun Dong
Keywords(s):  
Category(s): Technology Classifications > Engineering > Mechanical, Technology Classifications > Engineering > Chemical
Label-Free Detection Platform for CircRNAs
Circular RNAs (circRNAs) hold great potential as novel biological and clinical biomarkers for diagnosis and prognosis of cancer and other diseases. Conventional detection techniques such as northern blotting, microarray, qRT-PCR and RNA-seq suffer from many issues including low sensitivity and background noise, which limit the use of circRNA in clinical...
Published: 1/19/2024   |   Inventor(s): Hao Yan, Yang Xu, Shaopeng Wang, Zijian Wan, Liangxiao Chen
Keywords(s):  
Category(s): Life Science (All LS Techs), Medical Diagnostics/Sensors, Imaging, Advanced Materials/Nanotechnology, Biomaterials, Bioanalytical Assays, Chemistries & Devices, Cancer
Wireless power transfer via partially magnetized pavement
Design concept of partially magnetized pavement layer​ Invention Summary: Lack of access to charging infrastructure and longer charging time have limited electric vehicle (EV) adoption. One promising solution is to utilize inductively coupled power transfer (ICPT)-based wireless charging modules embedded in the pavement for dynamic charging....
Published: 6/13/2024   |   Inventor(s): Hao Wang, Lukai Guo
Keywords(s):  
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Energy & Battery
Multiple-DOF energy harvester from vibrations
Cantilevers with 1, 2 and 3 degrees of freedom​ Invention Summary: Piezoelectric energy harvesters mounted on bridges, pavements and other transportation infrastructure can potentially replace batteries for powering autonomous sensors by converting ambient kinetic energy into electric energy. Due to complications and uncertainties of vibration...
Published: 9/12/2024   |   Inventor(s): Hao Wang, Lukai Guo
Keywords(s):  
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Sensors, Technology Classifications > Energy & Battery
Label-free Multimetric Measurement of Molecular Binding Kinetics
Molecular interactions play an important role in cellular functions and biotechnology including cell signaling, enzymatic reactions, early disease diagnoses, and drug screening. Label-free techniques serve as important tools for studying these processes due to their ability to provide real-time information on binding kinetics without affecting the structure...
Published: 7/14/2023   |   Inventor(s): Shaopeng Wang, Guangzhong Ma, Xiaoyan Zhou
Keywords(s):  
Category(s): Imaging, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Bioanalytical Assays, Chemistries & Devices
Evanescent Scattering Imaging of Single Molecules
The ability to determine molecular binding is crucial in drug screening, biomarker detection, and understanding biological processes at the molecular level. Many methods for looking at binding kinetics, such as liquid chromatography, mass spectrometry, western blot, etc., are time consuming, cause protein fragmentation/denaturation and do not allow...
Published: 4/14/2023   |   Inventor(s): Shaopeng Wang, Pengfei Zhang
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Imaging, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
System for Single Protein Imaging and Analysis
The ability to determine molecular binding is crucial in drug screening, biomarker detection, and understanding biological processes at the molecular level. Many methods for looking at binding kinetics, such as liquid chromatography, mass spectrometry, western blot, etc., are time consuming, cause protein fragmentation/denaturation and do not allow...
Published: 4/14/2023   |   Inventor(s): Nongjian (nj) Tao, Shaopeng Wang, Pengfei Zhang
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Imaging
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