Search Results - benjamin+katchman

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Whole Tissue Protein Mapping
A tool and method for precise, high-throughput spatial mapping of proteins across whole tissue samples. Background: Spatial proteomics enables delineation of spatial localization of proteins within cells and tissues. This ability to identify and study the relative location and quantification of one or more proteins, whether ones that are endogenously...
Published: 8/21/2024   |   Inventor(s): Jun Qu, Ming Zhang, Min Ma
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Bioinformatics
Biomarkers for Early Detection of Serous Ovarian Cancer
Ovarian cancer is one of the most common cancers among women, with over 21,000 new cases and over 14,000 deaths per year. If detected early, the 5-year survival rate is over 80%, but that drops to just 11% if detected at stage IV, and over 60% of patients are diagnosed with advanced disease. Early detection is hampered by limitations in current biomarkers,...
Published: 2/23/2023   |   Inventor(s): Benjamin Katchman, Karen Anderson, Garrick Wallstrom, Joshua LaBaer, Daniel Cramer
Keywords(s): Antibodies, Autoantibody, Biomarker discovery, Cancer, Diagnostics, Early Detection, Immunosignature, Ovarian Cancer
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
QSOX1 as an anti-neoplastic drug target
Despite tremendous scientific progress and treatment advances, cancer continues to be the leading cause of death worldwide, with approximately 14 million new cases and 8.2 million deaths in 2012 alone (WHO). Because invasion and metastasis are arguably the most dangerous characteristics of cancer, therapeutics that suppress these characteristics could...
Published: 7/15/2024   |   Inventor(s): Douglas Lake, Benjamin Katchman
Keywords(s): Bio-Technology, Drug Screening, Therapeutics
Category(s): Cancer Therapeutics, Life Science (All LS Techs), Pharmaceuticals