Search Results - immunosignature

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Biomarkers for Early Detection of Serous Ovarian Cancer
Ovarian cancer is one of the most common cancers among women, with over 21,000 new cases and over 14,000 deaths per year. If detected early, the 5-year survival rate is over 80%, but that drops to just 11% if detected at stage IV, and over 60% of patients are diagnosed with advanced disease. Early detection is hampered by limitations in current biomarkers,...
Published: 2/23/2023   |   Inventor(s): Benjamin Katchman, Karen Anderson, Garrick Wallstrom, Joshua LaBaer, Daniel Cramer
Keywords(s): Antibodies, Autoantibody, Biomarker discovery, Cancer, Diagnostics, Early Detection, Immunosignature, Ovarian Cancer
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
Novel Antibodies for Detecting Gastric Cancer
Gastric cancer (GC) is a major public health problem in many countries, with more than 1 million new cases, worldwide, in 2018, contributing to almost 800,000 deaths. And new research suggests that GC may be on the rise in the US, particularly among younger adults. Early detection of GC often allows for greater therapeutic options, however, because...
Published: 2/23/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Lusheng Song, Yunro Chung
Keywords(s): Antibodies, Antibody Therapeutics, Bioanalysis, Bioassay, Cancer, Diagnostics, Immunosignature, Infectious Disease, Protein Assays
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Medical Diagnostics/Sensors
Conditioned Surfaces for In Situ Molecular Array Synthesis
Array technologies allow scientists to perform large-scale, quantitative, biological analyses such as biomarker discovery, immunomonitoring, epitope mapping and so on. In situ synthesized arrays have advantages in feature density, and sensitivity, however, quality and reliability rely on the quality and consistency of the synthesized molecules. A critical...
Published: 2/23/2023   |   Inventor(s): Neal Woodbury, Zhan-Gong Zhao
Keywords(s): Affinity Reagent, Immunosignature, MicroArray, Peptide Microarray
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools