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e
sign to manufacture polyamide reverse osmosis membrane using molecular layer-by-layer deposition
Thin-film composit
e
polyamide membranes, are the basis for modern commercial reverse osmosis (RO) membranes. These membranes are created through interfacial polymerization (IP) involving a trifunctional acid chloride (e.g., trimesoyl chloride, TMC, dissolved in an organic solvent) and a difunctional amine (e.g., m-phenylenediamine, MPD, dissolved in...
Published: 5/30/2025
|
Inventor(s):
Samarpan D
e
b Majumder
,
Xitong Liu
Keywords(s):
Category(s):
T
e
chnology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
,
T
e
chnology Classifications > Industrial or Consumer Tech > Industrial Manufacturing
Robot-Aid
e
d System And Method For Diagnosis Of Autism Spectrum Disorder
S
e
nsory abnormalities are reported to be central to autistic experience. The symptoms include hyposensitivity, hypersensitivity, multichannel receptivity, processing difficulties and sensory overload. Given the intensive and cumbersome nature of current methods of diagnosis, there is a need of behavior-based approach to identify the children at risk...
Published: 5/30/2025
|
Inventor(s):
Chung Hyuk Park
,
Hifza Jav
e
d
Keywords(s):
Category(s):
T
e
chnology Classifications > Diagnostics
,
T
e
chnology Classifications > Medical Devices > Therapeutic Devices
Tampa N
e
uromapping Depth Electrode
Advantag
e
s Combines recording and stimulation in a single device Reduces brain penetration and surgery time Lowers risk of hemorrhage, infection, and brain shift Enables precise brain mapping and real-time stimulation Summary Deep Brain Stimulation (DBS) helps patients with movement disorders like Parkinson’s disease by sending electrical...
Published: 5/30/2025
|
Inventor(s):
Oliv
e
r Flouty
,
Yar
e
ma Bezchlibnyk
,
Vishal Bharmauria
,
Nour Shah
e
en
,
Brian Dalm
,
Can Sarica
,
Matth
e
w Howard
,
Hiroto Kawasaki
,
Mario Zanaty
,
Al
e
x Green
,
Andr
e
s Lozano
Keywords(s):
Category(s):
T
e
chnology Classifications > Medical > Neuroscience
E
ngineering Asymmetrically Glycosylated IgG Antibodies
Application A nov
e
l method to develop asymmetrically glycosylated therapeutic monoclonal IgG antibodies for preventing and treating diseases like cancer, infectious diseases, and autoimmune disorders. Key Benefits Different IgG antibody glycoforms can be produced, each with its unique effector functions and biological and therapeutic effects. Potential...
Published: 5/30/2025
|
Inventor(s):
E
ric J. Sundberg
,
Jonathan Du
,
Tala Azzam
Keywords(s):
Antibodi
e
s
,
Immunology and Inflammation Tr
e
atments
,
Microbiology and Inf
e
ctious Disease Treatments
,
Oncology Tr
e
atments
Category(s):
T
e
chPub Algolia > Therapeutics
Companion Diagnostic for Immunomodulatory R
e
pair Treatments
This t
e
chnology is a diagnostic tool designed to help match patients to specific drugs or therapies to treat chronic ischemic heart failure. The platform focuses on immune cells called macrophages, which play a crucial role in the body's response to injury and disease. By promoting a specific type of macrophage known to aid healing, this system...
Published: 5/30/2025
|
Inventor(s):
St
e
ven Goldman
,
Dani
e
l Benson
,
Adrian Grijalva
,
Jordan Fink
,
Jordan Lancast
e
r
,
J
e
nnifer Koevary
,
Simar Singh
Keywords(s):
Category(s):
T
e
chnology Classifications > Life Sciences > Diagnostics
,
T
e
chnology Classifications > Research Tools > Screening assays
,
T
e
chnology Classifications > Healthcare Portfolios > Heart and Vascular
RNA Binding Motif 3 (RBM3) Ov
e
rexpressing Transgenic Mouse
Advantag
e
s • RBM3 upregulation reverses multiple tau phosphorylations post-TBI • Novel RBM3 Overexpressing Transgenic Mouse Model allows researchers to study the effects of RBM3 activation on tissue function, brain function, and brain injury Summary Traumatic brain injury (TBI) not only causes immediate neuronal damage but also...
Published: 5/30/2025
|
Inventor(s):
Travis Jackson
Keywords(s):
Animal Mod
e
ls
,
N
e
uroscience
Category(s):
T
e
chnology Classifications > Research Tools/Copyright > Animal Models
,
T
e
chnology Classifications > Medical > Neuroscience
,
T
e
chnology Classifications > Medical > Biotechnology
M
e
thod for Co-Localizing Two Proteins on the Inside of the Cell Membrane in Yeast
Advantag
e
s Localization of protein interactions at the cell membrane offers a more physiologically relevant model Improved screening by minimizing off-target interactions Broadly applicable and accessible tools Summary Protein-protein interactions involving membrane proteins are notoriously difficult to study under physiologically relevant conditions....
Published: 5/30/2025
|
Inventor(s):
Lawr
e
nce Stern
,
Micha
e
l Nelson
Keywords(s):
Drug Discov
e
ry
Category(s):
T
e
chnology Classifications > Medical > Cell & Tissue Engineering
,
T
e
chnology Classifications > Medical > Medical Diagnostics
,
T
e
chnology Classifications > Medical > Biomaterials
Transg
e
nic Foxc2-tdTomato Overexpressing Mouse Model for Study and Screening of Lymphatic Valve Development
Advantag
e
s Tissue specific Foxc2 expression with integrated tdTomato fluorescent reporter enables precise spatiotemporal visualization Enables monitoring of lymphatic valve development 1:1 co-expression of Foxc2 and tdTomato, overcoming expression variability characteristic associated with of IRES-based or viral delivery systems Single-vector...
Published: 5/30/2025
|
Inventor(s):
Joshua Scallan
Keywords(s):
Animal Mod
e
ls
Category(s):
T
e
chnology Classifications > Research Tools/Copyright > Animal Models
Synth
e
sis of Non-steroidal Anti-Inflammatory Compounds to Promote Wound Healing
Graph shows th
e
average skin punch biopsy weight of mice treated topically with nitrogen mustard (NM) to induce skin inflammation. Mice additionally treated with polyamine-imidazole conjugates showed a marked decrease in skin inflammation. Invention Summary: Non-steroidal Anti-Inflammatory drugs (NSAIDs) are widely available for over-the-counter...
Published: 5/30/2025
|
Inventor(s):
J
e
ffrey Laskin
,
N
e
d Heindel
,
Christoph
e
Guillon
Keywords(s):
Category(s):
T
e
chnology Classifications > Therapeutics
,
T
e
chnology Classifications > Healthcare & Life Sciences
R
e
purposed Receptor Blocker for the Treatment of PTSD
Application Us
e
of neurokinin 3 receptor antagonist, osanetant, for the prevention and treatment of post-traumatic stress disorder (PTSD) and other anxiety disorders. Key Benefits Utilizes a repurposed drug that is safe for human use. Potential to treat specific PTSD symptoms better than antidepressants. Market Summary Post-traumatic stress...
Published: 5/30/2025
|
Inventor(s):
K
e
rry Ressler
,
Raul And
e
ro Gali
Keywords(s):
N
e
urology and Pain Treatments
,
R
e
purposed Drug
Category(s):
T
e
chPub Algolia > Therapeutics
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