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M
e
thod of Treating Obesity-Induced Glucose Intolerance and Liver Fibrosis (UCLA Case No. 2021-323)
UCLA r
e
searchers in the School of Engineering have discovered a novel method to treat obesity-induced glucose intolerance and liver fibrosis. BACKGROUND: The CDC reports that 41.9% of adults ages 20 and over are obese. An increased incidence of obesity also increases the rates of comorbidities such at type 2 diabetes mellitus (T2DM), non-alcoholic...
Published: 9/24/2024
|
Inventor(s):
Zh
e
n Gu
Keywords(s):
glucos
e
intolerance
,
liv
e
r fibrosis
,
Nanoparticl
e
s
,
Notch signaling pathway
,
ob
e
sity
Category(s):
Th
e
rapeutics > Metabolism And Endocrinology
S
E
LECTIVE SENSITIZATION OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES
S
E
LECTIVE SENSITIZATION OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES Researchers at Stanford University have developed a novel method for the treatment and prevention of cancer. The immune system is an integral part of the human body’s response to outside threats, including cancer. Specifically, cytotoxic CD8+ T cells have been...
Published: 9/24/2024
|
Inventor(s):
R
e
ece Akana
Keywords(s):
Canc
e
r
,
Immuno-Oncology
,
T-C
e
ll Activation
Category(s):
T
e
chnology Classifications > Biology
COMPOSITIONS AND M
E
THODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS
COMPOSITIONS AND M
E
THODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS Researchers at Stanford University have developed a novel therapeutic avenue for the treatment of osteoporosis and other musculoskeletal diseases. Musculoskeletal disease incidence rates have increased in recent years in response to an aging population. Available...
Published: 9/24/2024
|
Inventor(s):
Charl
e
s Chan
,
Thomas Ambrosi
,
Irving W
e
issman
,
Micha
e
l Longaker
,
Rahul Sinha
,
D
e
bashis Sahoo
Keywords(s):
Hydrog
e
l
,
St
e
m Cell
Category(s):
T
e
chnology Classifications > Biology
D
E
SIGN OF UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION
D
E
SIGN OF UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION Researchers at Stanford University have developed novel universal vaccine candidates for H5 influenza viruses. Influenza remains a serious threat to public health. H5 avian influenza strains are among the most concerning despite lack of documented human to human...
Published: 9/24/2024
|
Inventor(s):
Duo Xu
,
P
e
ter Kim
Keywords(s):
Immunofocusing
,
Vaccin
e
Category(s):
T
e
chnology Classifications > Biology
NOV
E
L SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR
NOV
E
L SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR Researchers at Stanford University and Washington University have discovered a novel molecular pathway for the treatment of opioid overdose. Opioids are a powerful tool for pain management when used in clinical care settings. However, in recent years these drugs have...
Published: 9/24/2024
|
Inventor(s):
E
van Obrien
,
Kaavya Kumar
,
Brian Kobilka
,
Susruta Majumdar
,
Vipin Rangari
Keywords(s):
Opiod
,
Pain
Category(s):
T
e
chnology Classifications > Chemistry
C41 Analogs
This inv
e
ntion relates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024
|
Inventor(s):
W
e
i Wang
,
Rui Chang
,
Vijayan Ramachandran
,
Patrick Ronaldson
Keywords(s):
Category(s):
T
e
chnology Classifications > Healthcare Portfolios > Neurology
,
T
e
chnology Classifications > Life Sciences > Nutraceuticals
,
T
e
chnology Classifications > Life Sciences > Small Molecules
,
T
e
chnology Classifications > Life Sciences > Therapeutics
,
T
e
chnology Classifications > Life Sciences > Biologics
Stimulation D
e
vice to treat Hand Weakness from Stroke or Spinal Injury
A growing numb
e
r of people experience hand weakness due to stroke or spinal cord injuries. Electrical stimulation (e-stim) devices are commonly used to assist in hand weakness therapy. However, they are bulky, expensive, uncomfortable (may be ill-fitting, cause skin irritation or unpleasant sensation), and non-portable, eliminating the potential for...
Published: 9/24/2024
|
Inventor(s):
Atharva Wani
,
Nit
e
esh Nigam
,
Onkar Chavan
,
Yash B
e
llap
,
Jo
e
lly Lobato
,
Ishan Swanand Vyas
,
Suhrud Parag Jogl
e
kar
Keywords(s):
Category(s):
Lif
e
Science (All LS Techs)
,
M
e
dical Devices
,
Manufacturing/Construction/M
e
chanical
Vital Signs Monitoring using D
e
pth Cameras
Cardiovascular dis
e
ase is responsible for an estimated 17.9 million deaths each year, making it the leading cause of death worldwide. Continuous heart health monitoring way is the best preventative for heart failure. However, standard monitoring devices, including ECG and PPG, require direct physical contact, which can be difficult for certain patient...
Published: 9/24/2024
|
Inventor(s):
Yu Rong
,
Dani
e
l Bliss
Keywords(s):
Category(s):
Computing & Information T
e
chnology
,
M
e
dical Devices
,
Lif
e
Science (All LS Techs)
,
M
e
dical Diagnostics/Sensors
,
M
e
dical Imaging
H
e
ad Motion Correction with Soft Pressure Pad for MRI Scans
Addr
e
ssed Need Head motion remains a major challenge during medical imaging scans, particularly in pediatric and older patient populations. Motion impacts diagnostic image quality, costing both time and money in the clinical setting. In research, motion artifacts can introduce errors into quantitative measurements, especially in high-resolution or...
Published: 9/24/2024
|
Inventor(s):
Keywords(s):
Category(s):
M
e
dical Devices
,
M
e
dical Imaging
Inhibitors of th
e
N-terminal Domain of the Androgen Receptor (UCLA Case No. 2023-075)
R
e
searchers at UCLA under the guidance of Drs. Matthew Rettig and Michael Jung have developed novel molecular compounds that reduce growth of prostate cancer cells. Dr. Jung in collaboration with Dr. Rettig have furthered the development of these compounds by synthesizing a new series of analogues that have similar inhibitory effects. BACKGROUND: Prostate...
Published: 9/23/2024
|
Inventor(s):
Matth
e
w Rettig
,
Micha
e
l Jung
Keywords(s):
androg
e
n receptor therapy
,
castration r
e
sistant prostate cancer
,
Oncology
,
Oncology (Small Mol
e
cules, Peptides and Antibodies)
,
prostat
e
cancer
,
small mol
e
cules
Category(s):
Th
e
rapeutics > Oncology
,
Th
e
rapeutics > Oncology > Oncology (Small Molecules)
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