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Title
ID
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Non-invasiv
e
Diagnostic for Meningiomas
Application A non-invasiv
e
molecular diagnostic tool that reliably predicts the tumor characteristics and risk of recurrence of meningiomas. Key Benefits Combines meningioma gene expression data, construction of a gene interaction network, and tumor histology data to diagnose and predict clinical outcomes. Complete analytical handling from specimen...
Published: 1/28/2026
|
Inventor(s):
Ali Alawi
e
h
,
Youss
e
f Ismail
,
Tomas Garzon-Muvdi
Keywords(s):
Algorithm, AI, and Machin
e
Learning
,
Biomark
e
rs
,
Oncology Tr
e
atments
,
P
e
rsonalized Medicine
,
Platform
,
Scr
e
ening Assays
Category(s):
T
e
chPub Algolia > Diagnostics
Sulfonyl-triazol
e
activators for cell-selective glycolysis enhancement in cancer and Parkinson’s disease
Background C
e
llular metabolism is a central regulator of immune cell function and neuronal survival, making it a promising therapeutic target in both cancer and neurodegenerative disease. In solid tumors, tumor-infiltrating lymphocytes (TILs) frequently succumb to metabolic exhaustion due to the nutrient-depleted and immunosuppressive microenvironment,...
Published: 1/27/2026
|
Inventor(s):
Ku-Lung Hsu
,
Xiaoding Jiang
,
Xiaolu Cambronn
e
Keywords(s):
Category(s):
Lif
e
sciences > Therapeutics > Formulation
,
Lif
e
sciences > Therapeutics > Drug discovery
Micron
e
edle array coating technology for enhanced stability and targeted delivery of mRNA and biologics
A micron
e
edle-based system uses cryogenically pre-cooled needles coated via thin-film freeze-coating to preserve mRNA stability, enabling efficient, multi-therapeutic intradermal delivery of temperature-sensitive drugs. Background The field of advanced drug delivery systems has grown substantially as the biomedical industry grapples with the complexities...
Published: 1/27/2026
|
Inventor(s):
Zh
e
ngrong Cui
,
Micha
e
l Sandoval
,
Rob
e
rt Williams
,
Dr
e
w Weissman
,
Qin Li
Keywords(s):
Category(s):
Lif
e
sciences > Therapeutics > Drug discovery
A micron
e
edle-based resonant sensor system for continuous, wireless monitoring of wound and physiological states
This t
e
chnology uses gold-coated microneedles and wireless sensors to directly sample wound fluid, detecting infection and other changes in real time. Data is analyzed with machine learning and sent to clinicians for early, continuous wound monitoring. Background Wound monitoring is a critical aspect of healthcare, especially for patients recovering...
Published: 1/27/2026
|
Inventor(s):
Jam
e
s Clarke
,
Mil
e
s Massidda
,
Jos
e
ph Schmidt
,
Cristina Ch
e
cka
,
Scott Alpard
Keywords(s):
Category(s):
Lif
e
sciences > Medical technology > Medical devices
Misalignm
e
nt Resilient Diffractive Optical Networks (Case No. 2020-885)
Summary: UCLA r
e
searchers in the Department of Electrical and Computer Engineering have developed and experimentally validated a comprehensive training scheme that greatly enhances the robustness of diffractive networks to 3D misalignments and fabrication tolerances in their physical implementation. Background: As an optical machine learning framework,...
Published: 1/28/2026
|
Inventor(s):
Aydogan Ozcan
Keywords(s):
Optical Communication
,
Optical computing
,
optical impl
e
mentation
,
Optical n
e
tworks
,
optical proc
e
ssor
Category(s):
Softwar
e
& Algorithms
,
Softwar
e
& Algorithms > Image Processing
,
Optics & Photonics
Antibody compositions for improving d
e
tection and treatment of
Bacillus anthracis
infections
This t
e
chnology uses specially designed antibodies with enhanced ability to detect or treat Bacillus anthracis infections, improving both diagnosis and therapy for anthrax. Background Bacillus anthracis, the causative agent of anthrax, is a highly virulent bacterium that poses significant threats to both public health and national security. Anthrax...
Published: 1/27/2026
|
Inventor(s):
G
e
orge Georgiou
,
Br
e
nt Iverson
,
Barr
e
tt Harvey
Keywords(s):
Category(s):
Lif
e
sciences > Immunology
,
Lif
e
sciences > Therapeutics
E
ngineered enzyme therapy for targeted reduction of plasma homocysteine in metabolic disorders
This t
e
chnology is a specially engineered human enzyme, modified and PEGylated to break down excess homocysteine in the blood, offering a new treatment for homocystinuria and hyperhomocysteinemia with improved effectiveness and dosing flexibility. Background Homocystinuria and hyperhomocysteinemia are metabolic disorders characterized by elevated...
Published: 1/27/2026
|
Inventor(s):
Scott Rowlinson
,
Christoph
e
r Daige
,
L
e
slie Sloan
Keywords(s):
Category(s):
Lif
e
sciences > Therapeutics > Small molecule
R
e
gulated Gene Expression During Differentiation of Mature T Cells (UCLA Case No. 2022-147)
UCLA r
e
searchers from the Department of Pathology & Laboratory Medicine have developed a process to genetically modify stem cells to express transgenes in a regulated, stage-specific manner, avoiding the negative consequences of transgene expression during T cell development. Contact UCLA Technology Development Group for more information.
Published: 1/27/2026
|
Inventor(s):
Gay Crooks
,
Donald Kohn
Keywords(s):
Category(s):
Th
e
rapeutics > Gene Therapy And Editing
,
Th
e
rapeutics > Stem Cells And Regenerative Medicine
,
Th
e
rapeutics > Oncology
,
Th
e
rapeutics > Immunology And Immunotherapy
,
Th
e
rapeutics > Inflammation And Inflammatory Diseases
E
nhancing T Cell Production in Vitro From Stem and Progenitor Cells (UCLA Case No. 2022-257)
UCLA r
e
searchers from the Department of Pathology and Laboratory Medicine have developed an innovative differentiation method to increase T cell production for T cell immunotherapy. Contact UCLA Technology Development Group for more information.
Published: 1/27/2026
|
Inventor(s):
Gay Crooks
,
Christoph
e
r Seet
Keywords(s):
Category(s):
Th
e
rapeutics > Oncology
,
Th
e
rapeutics > Immunology And Immunotherapy
Insulin Crystals R
e
moval Platform
D
e
scription: A platform technology for improving insulin delivery by removing insulin-derived fibrils through polyester membrane filtration. This invention employs membrane filters integrated into insulin delivery systems to selectively remove insulin-derived fibrils (IDFs) from insulin formulations. By filtering out fibrils while preserving active...
Published: 1/27/2026
|
Inventor(s):
Ulrik
e
Klueh
Keywords(s):
Category(s):
T
e
chnology Category > Biomedical
,
T
e
chnology Category > Devices
,
T
e
chnology Category > Drug Delivery
,
T
e
chnology Category > Life Science
,
T
e
chnology Category > Medical Devices
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