Search Results - yanyun+zhao

16 Results Sort By:
Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth
An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...
Published: 10/1/2025   |   Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij
Keywords(s): Driving Lifelong Health
Category(s): Technology Category > Women's Health, Technology Category > Medical Devices, Technology Category > Life Science, Technology Category > Imaging, Technology Category > Acoustics
Hydrogen Sulfide Releasing Agents
Abstract Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state-of-the-art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological...
Published: 6/4/2025   |   Inventor(s): Ming Xian, Hua Wang, Yu Zhao
Keywords(s): Chemistry
Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Health & Well-being > Pharmaceutical
DNA Gridiron
Self-assembling nucleic acid molecules have been utilized extensively for constructing unique nanoscale structures, and designing increasingly complex structures is a top nanotechnology challenge. Current methods to create NDA nanostructures are restricted to discrete domains of parallel lines as a result of the double crossover based unit motif, which...
Published: 2/26/2026   |   Inventor(s): Dongran Han, Hao Yan
Keywords(s): DNA nanotechnology
Category(s): Advanced Materials/Nanotechnology, Life Science (All LS Techs), Biomaterials, Chemical/Biological Sensors, Genomic Assays/Reagents/Tools
Tumor-Targeted Killing with Aptamer-Nucleic Acid Nanostructures
Despite decades of research, cancer remains one of today’s most pressing health concerns. Traditional treatment approaches such as radiation therapy and chemotherapy can cause systemic toxicity and become ineffective when resistant tumors emerge. Recently, anticancer strategies have focused on drugs which specifically target tumor-related biological...
Published: 2/26/2026   |   Inventor(s): Yung Chang, Hao Yan
Keywords(s): Bio-Technology, Drug Screening, Therapeutics
Category(s): Life Science (All LS Techs), Cancer Therapeutics, Genomic Assays/Reagents/Tools
DNA Nanocaged Enzymes
Compartmentalization increases the overall activity and specificity of encapsulated enzymes by protecting the enzymes, maintaining a high concentration of enzymes and substrates, and promoting substrate channeling. While there have been artificial enzymatic particles that have been created using compartmentalization by virus-like proteins, liposomes,...
Published: 2/26/2026   |   Inventor(s): Jinglin Fu, Hao Yan, Neal Woodbury, Zhao Zhao
Keywords(s): Bioanalysis, Catalysis, Enzymes
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors
DNA Nanocaged Enzymes
Compartmentalization increases the overall activity and specificity of encapsulated enzymes by protecting the enzymes, maintaining a high concentration of enzymes and substrates, and promoting substrate channeling. While there have been artificial enzymatic particles that have been created using compartmentalization by virus-like proteins, liposomes,...
Published: 2/26/2026   |   Inventor(s): Jinglin Fu, Hao Yan, Neal Woodbury, Zhao Zhao
Keywords(s): Bioanalysis, Catalysis, Enzymes
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors
Biological H2S / COS Donation by Thiocarbamates
1. Technology Overview The invention focuses on biological hydrogen sulfide (H₂S) and carbonyl sulfide (COS) donation using thiocarbamates. These compounds release COS, which is then converted to H₂S by hydrolysis or metabolism by carbonic anhydrase. The technology is currently in the development stage, with promising cross-industry applications in...
Published: 1/7/2026   |   Inventor(s): Michael Pluth, Andrea Steiger, Yu Zhao
Keywords(s):  
Category(s): Chemistry, Physical Science, Therapeutics
Compounds for Thiol-Triggered COS and/or H2S Release and Methods of Making and Using the Same
1. Technology Overview The invention focuses on thiol-triggered sulfenyl thiocarbonates and sulfenyl thiocarbamates that release carbonyl sulfide (COS) and hydrogen sulfide (H₂S) in the presence of biologically relevant thiols. These compounds offer a concomitant fluorescence response, providing optical indication of COS and H₂S release. The technology...
Published: 1/2/2026   |   Inventor(s): Michael Pluth, Yu Zhao, Matt Cerda
Keywords(s): Science
Category(s): Chemistry, Engineering, Medical Devices, Physical Science, Therapeutics
Infusion of Food Grade Coatings with Propylene Glycol into Ham Nets to Control Pest Infestations
Overview of Technology Food grade, sustainable coating formulations can be combined with nets to protect foods from pests during curing processes. Dry-cured ham is extremely susceptible to mold mite infestations during the aging process due to its moldy surface buildup and high fat and protein composition. Currently, Methyl bromide is the only fumigant...
Published: 6/10/2022   |   Inventor(s): Mark (Wes) Schilling, Yan Zhao, Yan Campbell, Thomas Phillips, Salehe Abbar, Barbara Amoah
Keywords(s): Food
Category(s): Agriculture & Food Science
Synbodies - High Throughput Development of Synthetic Antibodies
The development of new drugs and diagnostic assays requires the ability to identify and prepare high-affinity, high-specificity ligands. Monoclonal antibodies are useful reagents in this regard, but are difficult to humanize and express in large amounts. Monoclonal antibodies are also intrinsically limited by the immunological repertoire of the immunized...
Published: 2/26/2026   |   Inventor(s): Stephen Johnston, Neal Woodbury, John Chaput, Chris Diehnelt, Hao Yan
Keywords(s):  
Category(s): Life Science (All LS Techs), Diagnostic Assays/Devices, Bioanalytical Assays, Chemistries & Devices, Proteomic Assays/Reagents/Tools
1 2