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THE CHALLENGE A major unmet need in the opioid overdose response market stems from the rapid rise of synthetic opioids such as fentanyl and the limitations of current antidote delivery solutions. Although naloxone is widely used as an opioid antagonist, existing nasal and injectable formats depend on bystander recognition and manual administration,...

Published: 6/9/2026 | Updated: 6/9/2026 | Inventor(s): Wujin Sun, Penghui Zhao

Keywords(s):

Category(s): Technology Classifications > Biotechnology

Negative Pressure-Assisted DNA Delivery

Fig.1. Dermal suction induces long-lasting antigen expression and T-cell response. (A) Dermal suction via a small hand-held device with a 6-mm orifice against the skin. Inset: immune response is 100 times stronger when compared with injection alone. (B) Post-suction skin demonstrates no damage nor erythema. (C) and (D): Benchmarking of suction against...

Published: 5/15/2026 | Updated: 5/15/2026 | Inventor(s): Hao Lin, Jonathan Singer, David Shreiber, Jerry Shan, Jeffrey Zahn, Emran Lallow, Juliet Melnik, Nandita Jhumur

Keywords(s): Drug Delivery

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Vaccine

Development of Antimicrobial Peptidomimetics Based on Helical Sulfonyl-γ-AA Peptides with Broad-Spectrum Activity Against Multidrug-Resistant Pathogens

Advantages Demonstrates broad spectrum antibacterial activity against both Gram-positive and Gram-negative multidrug resistant pathogens Designed to mimic natural antimicrobial peptides (AMPs) while overcoming their limitations Exhibits enhanced structural stability and resistance to proteolytic degradation, leading to prolonged activity Acts...

Published: 5/15/2026 | Updated: 5/15/2026 | Inventor(s): Xue Zhao, Jianfeng Cai

Keywords(s): Anti-Microbials, Infectious Diseases Treatment

Category(s): Technology Classifications > Medical > Infectious Diseases

UWB-PostureGuard: A Privacy-Preserving RF Sensing System for Continuous Ergonomic Sitting Posture Monitoring

UWB-PostureGuard is an ergonomic posture monitoring technology that continuously detects sitting posture without cameras or wearable devices, while preserving user privacy. The technology is designed for real-time use in everyday desk and seated work environments, providing posture awareness and enabling timely feedback when sustained or potentially...

Published: 4/28/2026 | Updated: 4/28/2026 | Inventor(s): Haotang Li, Zhenyu Qi, Sen He, Kebin Peng, Sheng Tan, Yili Ren, Tomas Cerny, Jiyue Zhao, Zi Wang

Keywords(s):

Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Human Machine Interface, Technology Classifications > Healthcare Portfolios, Technology Classifications > Imaging & Optics > Sensors and Detection > Remote Sensing

Methods To Regulate Metabolism For Treatment Of Neural Injuries and Neurodegeneration

Description of Technology: Axonal injury and subsequent neuronal death underpin the pathology of many neurological disorders from acute neural injuries (motor vehicle crashes, combat related injuries, traumatic brain injuries) to neurological diseases (multiple sclerosis, glaucoma). In the central nervous system (CNS), microglia help respond to CNS...

Published: 4/16/2026 | Updated: 4/16/2026 | Inventor(s): Wei Li, Jingxing Ou, Tantai Zhao

Keywords(s):

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Neurology, Collaboration Sought > Licensing

A Smartwatch-integrable, non-invasive RF bioimpedance wearable system for continuous, equitable blood pressure monitoring

This technology is a smartwatch-compatible, low-power wearable that uses radio frequency bioimpedance and AI to continuously and non-invasively monitor blood pressure, offering accurate, skin color-independent readings and robust performance compared to traditional optical sensors. Background Blood pressure (BP) monitoring is a cornerstone of cardiovascular...

Published: 4/14/2026 | Updated: 4/14/2026 | Inventor(s): Deji Akinwande, Neelotpala Kumar, Solomon Leo, Jiahui Zhao, Sophie Lalande

Keywords(s):

Category(s): Life sciences > Medical technology > Medical devices

Determining the Percentage of Recycled Plastic Content in a Plastic Product

A device to determine the percentage of recycled plastic content in a manufactured plastic product. BACKGROUND: As global plastic waste continues to rise, accurately identifying and quantifying recycled content in plastic products is critical for developing a circular economy. At present, there is no method that can accurately determine the percentage...

Published: 4/30/2026 | Updated: 4/7/2026 | Inventor(s): Amit Goyal, Thomas Thundat, Yaoli Zhao, Charuvahan Adhivarahan, Karthik Dantu, Chandra Lekha Jyothula

Keywords(s): Featured, Technologies

Category(s): Campus > University at Buffalo, Technology Classifications, Technology Classifications > Environment, Technology Classifications > Instrumentation, Technology Classifications > Sensors

Monolithically-Integrated Terahertz Optoelectronics on Quantum Well Substrates (UCLA Case No. 2024-280)

UCLA researchers have developed a monolithically integrated terahertz optoelectronic platform that enables both THz generation and detection on a single chip. This approach offers a compact, scalable solution for applications in wireless communication, imaging, and spectroscopy, overcoming long-standing barriers in THz system complexity and integration. BACKGROUND:...

Published: 3/26/2026 | Updated: 3/26/2026 | Inventor(s): Mona Jarrahi, Yifan Zhao

Keywords(s):

Category(s): Optics & Photonics > Spectroscopy, Materials > Semiconducting Materials, Electrical > Electronics & Semiconductors, Electrical > Sensors, Electrical > Wireless

Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels

This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...

Published: 5/1/2026 | Updated: 3/23/2026 | Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays

A Method for Generating Functional Surface Coatings and Modifications via Self-Assembly of Silk Fibroin and Silk Fibroin-Like Macromolecules

RPI ID: 2019-087-401 Innovation Summary: A non-covalent, bottom-up coating method enables the formation of silk fibroin-based layers on chemically inert and geometrically complex surfaces. The process uses kosmotropic agents to facilitate smooth, homogeneous coatings that are tunable in thickness and free of inhomogeneities. These coatings can incorporate...

Published: 4/9/2026 | Updated: 3/10/2026 | Inventor(s): Runye Zha, Tanner Fink, Caleb Wigham

Keywords(s): antifouling coatings, bioinert, Biomaterial, biomedical coatings, Implant, implant surface, protein structure, Self Assembly, silk, spidroin, Surface modification, surface treatment, thin film coatings, universal coating

Category(s): Biotechnology and the Life Sciences

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