Search Results - michael+pluth

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y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability

Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...

Published: 9/25/2023 | Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA

Keywords(s): Drug Discovery, Immunology

Category(s): Technology Classifications > Medical > Biotechnology

Biological H2S / COS Donation by Thiocarbamates

University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in...

Published: 5/2/2022 | Inventor(s): Michael Pluth, Andrea Steiger, Yu Zhao

Keywords(s):

Category(s): Chemistry, Physical Science, Therapeutics

A new method for detection for hydrosulfide anion (HS-) and hydrogen sulfide (H2S)

Hydrogen sulfide (H2S), although generally known for its toxicity and characteristic odor, is now recognized as an important signaling molecule with diverse biological roles. The biological roles of H2S range from roles in angiogenesis to wound healing. In mammals, H2S production is derived primarily from three enzymes: cystathionine-γ-lyase...

Published: 4/17/2024 | Inventor(s): Michael Haley, Darren Johnson, Michael Pluth, Ryan Hansen, Matt Hartle, Blakely Tresca

Keywords(s):

Category(s): Chemistry, Materials Science, Nanoscience & Microtechnologies, Physical Science, Imaging

Compounds for Thiol-Triggered COS and/or H2s Release and Methods of Making and Using the Same

Published: 5/2/2022 | Inventor(s): Michael Pluth, Yu Zhao, Matt Cerda

Keywords(s): Science

Category(s): Chemistry, Engineering, Medical Devices, Physical Science, Therapeutics

Thionoesters that Release H2S upon Thiol Ligation

Published: 5/2/2022 | Inventor(s): Michael Pluth, Matt Cerda

Keywords(s): Science

Category(s): Chemistry, Diagnostics, Medical Devices, Physical Science, Therapeutics

Gamma-ketothiocarbamate molecules that release COS

Published: 5/2/2022 | Inventor(s): Michael Pluth, Yu Zhao

Keywords(s):

Category(s): Chemistry, Diagnostics, Engineering, Medical Devices, Physical Science, Research Tools, Therapeutics

Network-Coded Multiple Access

[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...

Published: 1/29/2024 | Inventor(s): Soung Chang Liew, Lu LU, Lizhao You

Keywords(s): Network Coding, Wireless Local Area Network

Category(s): Information and Communications Technology

Chemiluminescent Probe for H2S Detection

Hydrogen sulfide is an important biological signalling molecule and an important environmental detection target. Biological H2S exhibits significant effects in both the cardiovascular and neuronal systems and is produced endogenously from cystathionine-β-synthase (CBS), cystathionine-gamma-lyase (CSE), and 3-mercaptopyruvate sulfur transferase...

Published: 10/1/2021 | Inventor(s): Michael Pluth, Thomas "spencer" Bailey

Keywords(s):

Category(s): Chemistry

Colorimetric H2S Detection

Published: 10/1/2021 | Inventor(s): Michael Pluth, Taylor Pearce, Leticia Montoya

Keywords(s):

Category(s): Chemistry