Search Results - matt+cerda

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Personalized Medicine Using Additive Manufacturing
THE CHALLENGE A major problem posed by the pharmaceutical industry is giving effective dosages while not giving excessive amounts of a particular drug. An estimated 80% of side effects in humans and animals are a direct result of inaccurate dosing because varying weights in patients. Additive manufacturing has emerged as a very promising method to...
Published: 6/26/2025   |   Inventor(s): Emily Wilts, Timothy Long, Christopher Williams, Da Ma
Keywords(s):  
Category(s): Technology Classifications > Additive Manufacturing, Technology Classifications > Biomedical, Technology Classifications > Chemicals/Materials, Technology Classifications > Pharmacology and Therapeutics
Compounds for Thiol-Triggered COS and/or H2S Release and Methods of Making and Using the Same
1. Technology Overview The invention focuses on thiol-triggered sulfenyl thiocarbonates and sulfenyl thiocarbamates that release carbonyl sulfide (COS) and hydrogen sulfide (H₂S) in the presence of biologically relevant thiols. These compounds offer a concomitant fluorescence response, providing optical indication of COS and H₂S release. The technology...
Published: 1/2/2026   |   Inventor(s): Michael Pluth, Yu Zhao, Matt Cerda
Keywords(s): Science
Category(s): Chemistry, Engineering, Medical Devices, Physical Science, Therapeutics
Thionoesters that Release H2S upon Thiol Ligation
1. Technology Overview The invention focuses on synthesizing thionoesters that release hydrogen sulfide (H₂S) upon thiol ligation. These small molecules react with L-cysteine and other cysteine derivatives to release H₂S, terminating in the formation of N-benzoyl-L-cysteine. The technology is currently in the development stage, with promising cross-industry...
Published: 1/7/2026   |   Inventor(s): Michael Pluth, Matt Cerda
Keywords(s): Science
Category(s): Chemistry, Diagnostics, Medical Devices, Physical Science, Therapeutics