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Edema Factor Adenylate Cyclase Variants Having Potencies That Are Highly Dependent On the N-end Rule
B. anthracis strains BH480; plasmids encoding anthrax edema factor (EF) variants pSJ136EFOS, pSJ 136EFA and pSJ 136EFR.
Published: 10/28/2024   |   Inventor(s): Clinton Leysath, Stephen Leppla
Keywords(s): ADENYLATE, Are, CYCLASE, DD1XXX, Dependent, Edema, factor, Having, Highly, Highlydependent, Listed LPM Soukas as of 4/15/2015, N-END, Post LPM Assignment Set 20150420, Potencies, Pre LPM working set 20150418, RM, RULE, That, VARIANTS, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Infectious Disease
Polyclonal and Monoclonal Antibodies to Human Eosinophil Major Basic Protein, Eosinophil Peroxidase, Eosinophil Cationic Protein, and Eosinophil-Derived Neurotoxin
Reagents particularly useful in configuring multiplex assays for simultaneous measurement and quantification of multiple eosinophil granule proteins and for immunohistochemistry. Ultimately these reagents may be used as diagnostics for many eosinophil-mediated disorders.
Published: 10/28/2024   |   Inventor(s): Richard Davey, Thomas Nutman
Keywords(s): antibodies, BASIC, CATIONIC, EOSINOPHIL, Eosinophil-Derived, Eosionophil, Human, Listed LPM Fenn as of 4/15/2015, MAJOR, monoclonal, Neurotoxin, PEROXIDASE, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Protein, RM, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials
WR (Western Reserve) Strain of Vaccinia Virus with K151E Mutation in A34R Gene
Mutation in gene A34R can regulate the release of progeny virions from the surface of parental cells.
Published: 10/28/2024   |   Inventor(s): Rafael Blasco, Bernard Moss
Keywords(s): A34, AC4XXX, AC5XXX, ACXXXX, AXXXXX, Cell, DDXXXX, DISSOCIATION, DXXXXX, GCXXXX, GLYCOPROTEIN, MEMBRANE, Progeny, REGULATED, research, RESEARCH MATERIAL, research reagent, RESEARCH TOOL, RM, RXXXXX, vaccinia, viral, virus, WIXXXX, XEXXXX, XKXXXX
Category(s): Collaboration Sought > Licensing, Application > Vaccines, Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease
Resurfaced Stabilized Core 3 (RSC3) Protein, Derived Proteins, and DNA Encoding These Proteins: RSC3, RSC3 delta371I, RSC3 delta371I/P363N, RSC3 G367R
Details for these materials may be found in the NIH AIDS Reagent Program Catalog – RSC3 (Catalog# 12042): https://www.aidsreagent.org/reagentdetail.cfm?t=proteins&id=214 RSC3 delta371I (Catalog# 12043): https://www.aidsreagent.org/reagentdetail.cfm?t=proteins&id=146 RSC3 delta371I/P363N (Catalog# 12362): https://www.aidsreagent.org/reagentdetail.cfm?t=proteins&id=145 RSC3...
Published: 10/28/2024   |   Inventor(s): Tongqing Zhou, Gary Nabel, Zhi-yong Yang, Ling Xu, Peter Kwong
Keywords(s): 3, Core, DERIVED, DNA, Encoding, Protein, proteins, Resurfaced, RM, RSC3, Stabilized, THESE, WIXXXX
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials
Expression, Purification, and Validation of Anthrax Toxin Proteins
Expression, purification, and validation of anthrax toxin proteins.
Published: 10/28/2024   |   Inventor(s): Rasem Fattah, Stephen Leppla
Keywords(s): Anthrax, Expression, proteins, purification, RM, toxin, Validation, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials
CCR9 Knockout Mice
Ccr9-/- mice may be useful for studying the role of CCR9 in T lymphocyte development and migration. Mice will be distributed by The Jackson Laboratory; details about this mouse strain (Stock No. 027041) may be found at https://www.jax.org/strain/027041.
Published: 10/28/2024   |   Inventor(s): Paul Love, Shoji Uehara, Joshua Farber
Keywords(s): CCR9, Distribution, Jackson, Knockout, Laboratories, Mice, RM, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials
Amino Acid Substitutions Mutants of Anthrax Protective Antigen, Lethal Factor, and Edema Factor
Anthrax toxin proteins available for licensing. Bacillus anthracis hosts containing plasmids expressing the following proteins are available. (Host strains are generally BH480, or sometimes BH460. Modest amounts of purified proteins (10-50 mg) could also be provided): PA. Protective antigen, wild type PA-3M (PA D683A, L685E, Y688K) PA-3M Cys PA-U7 PA...
Published: 10/28/2024   |   Inventor(s): Stephen Leppla
Keywords(s): Acid, AMINO, Anthrax, ANTIGEN, Edema, factor, Lethal, Listed LPM Ano as of 4/15/2015, Mutants, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Protective, RM, SUBSTITUTIONS, VJXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Research Materials
RL-5 – Rabbit T Cell Line Derived From a Herpesvirus Ateles-induced Rabbit Tumor From the Inbred Rabbit Line B/J
Details for this material are provided in the NIH AIDS Reagent Program Catalog (Catalog# 341): https://www.aidsreagent.org/reagentdetail.cfm?t=cell_lines&id=152.
Published: 10/28/2024   |   Inventor(s): Bishop Hague
Keywords(s): Ateles-induced, B/J., Cell, DERIVED, HERPESVIRUS, Inbred, Line, Listed LPM Ano as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, rabbit, RL-5-, RM, T, tumor, VLXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, TherapeuticArea > Infectious Disease, Application > Research Materials
Non-invasive Method for Ebola Virus Infection Detection in Great Apes and Other Wildlife Hosts
Ebola virus surveillance in wildlife vectors of infection transmission to humans.
Published: 10/28/2024   |   Inventor(s): Nancy Sullivan
Keywords(s): ACXXXX, Apes, Detection, Ebola, HOSTS, HostsNon-invasive, Humans, Infection, Method, NON-INVASIVE, Nucleoprotien, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, primate, RM, Surveillance, TRANSMISSION, vectors, virus, VLXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Research Materials
Recombinant LL-SXP-1 and Plasmid Encoding LL-SXP-1 for the Immunodiagnosis of Loa Loa
A Loa loa specific antigen that can be used as the basis of an immunoassay for the diagnosis of Loa loa infection.
Published: 10/28/2024   |   Inventor(s): Amy Klion, Thomas Nutman
Keywords(s): Immunodiagnosis, LL-SXP1, Loa, RM, VQXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Infectious Disease
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