Search Results - ebola

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Anti-Viral Polypeptide Griffithsin: Compounds, Compositions, and Methods of Use
Abstract: This technology describes additional methods of using the griffithsin anti-viral polypeptides described in related NCI invention (reference number E-106-2003).  Specifically, this invention describes the use of GRFT to inhibit viral infection of hepatitis C viral infection, a severe acute respiratory syndrome (SARS) viral infection, an H5N1...
Published: 4/8/2024   |   Inventor(s): Barry O'Keefe, James McMahon, Toshiyuki Mori
Keywords(s): Anti-Viral, Corona virus, Ebola, Griffithsin, INFLUENZA, O’Keefe, SARS
Category(s): TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Application > Therapeutics, Collaboration Sought > Licensing
Non-invasive Method for Ebola Virus Infection Detection in Great Apes and Other Wildlife Hosts
Ebola virus surveillance in wildlife vectors of infection transmission to humans.
Published: 10/28/2024   |   Inventor(s): Nancy Sullivan
Keywords(s): ACXXXX, Apes, Detection, Ebola, HOSTS, HostsNon-invasive, Humans, Infection, Method, NON-INVASIVE, Nucleoprotien, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, primate, RM, Surveillance, TRANSMISSION, vectors, virus, VLXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Research Materials
Nucleic Acid Primers and Probes for Detecting Ebola Virus (species Zaire ebolavirus)
The 2014-2016 Ebola Virus Disease (EVD) outbreak in West Africa was the largest in history, causing more than 28,000 suspected, probable, and confirmed infections and more than 11,000 deaths across nine countries. CDC scientists designed nucleic acid primers and probes which can be used in a sensitive test for detecting all known strains of Ebola virus...
Published: 10/28/2024   |   Inventor(s): Tara Sealy, Ute Stroeher, Stuart Nichol, Jonathan Towner
Keywords(s): 7, Acid, antibodies, ANTIGENS, assay, DETECTING, Detection, Ebola, Ebolavirus, ELISA, Enzyme, Identification, immunosorbent, LINKED, Listed LPM Kirby as of 4/15/2015, Mab, monoclonal, Mouse, NCEZID, NCEZID-DHCPP, Nucleic, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PRIMERS, Probes, Species, Used, virus, Viruses, Zaire
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Multivalent Vaccines for Rabies Virus and Filoviruses
No vaccine candidates against Ebola virus (EBOV) or Marburg virus (MARV) are nearing licensure and the need to develop a safe and efficacious vaccine against filoviruses continues. Whereas several preclinical vaccine candidates against EBOV or MARV exist, their further development is a major challenge based on safety concerns, pre-existing vector immunity,...
Published: 10/28/2024   |   Inventor(s): Jason Paragas, Reed Johnson, Peter Jahrling, Joseph Blaney
Keywords(s): Against, Bivalent, Confer, DA4BXX, DA4XXX, DAXXXX, DC5BXX, DC5XXX, DC6XXX, DCXXXX, DDXXXX, Dual, DXXXXX, Ebola, Ebola virus disease, INACTIVATED, Live-Attenuated, Marburg hemorrhagic fever, Protection, rabies, That, UAXXXX, vaccines, Viruses
Category(s): Collaboration Sought > Licensing, Application > Vaccines, TherapeuticArea > Infectious Disease, Application > Diagnostics, Application > Research Materials, TherapeuticArea > Rare / Neglected Diseases
Human-derived Monoclonal Antibody for Treatment of Ebola Virus Infection
Ebola virus infection can lead to severe hemorrhagic fever, known as Ebola virus disease (EVD), which is often fatal. The Zaire species of Ebola virus (EBOV) was responsible for the largest Ebola outbreak in history, which occurred in 2014. Scientists at the NIAID Vaccine Research Center have developed a human monoclonal neutralizing antibody, mAb114...
Published: 10/28/2024   |   Inventor(s): Antonio Lanzavecchia, Davide Corti, Barney Graham, Julie Ledgerwood, John Trefry, Daphne Stanley, Jean-Jacques Muyembe-Tamfun, Sabue Mulangu, Nancy Sullivan
Keywords(s): antibodies, Ebola, Ebolavirus, GLYCOPROTEIN, Listed LPM Thalhammer-Reyero as of 4/15/2015, monoclonal, Neutralize, Novel, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, That, THEREOF, USES, virus
Category(s): Collaboration Sought > Licensing