Search Results - polyclonal

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Detecting Levels of Chymotrypsin and Amylase using Rabbit Polyclonal Antibodies Generated from Purified Human Enzymes

The invention relates to rabbit antisera raised against purified human chymotrypsin and amylase. Both chymotrypsin and amylase are produced by the pancreas and play important roles in digestion. Abnormal levels of chymotrypsin and amylase have been known to occur with multiple pancreas-related disorders, including pancreatitis. Measuring levels of these...

Published: 10/28/2024 | Inventor(s): David Jacobowitz

Keywords(s): Amylase, antibodies, Chymotrypsin, Human, Listed LPM Maddox as of 4/15/2015, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, rabbit, VPXXXX, WBXXXX, WIXXXX, XAXXXX

Category(s): TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Antibodies, Application > Diagnostics, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, TherapeuticArea > Endocrinology, TherapeuticArea > Dental

Development of a Polyclonal Antibody for Neuroligin 4 pThr707 and a Polyclonal Antibody for Neuroligin 1 pTHR739

This invention includes the generation and use of two polyclonal antibodies that specifically recognizes the phosphorylation site pThr707 of Neuroligin 4 and pThr739 of Neuroligin 1. A peptide of the site around the phosphorylation site was generated and injected into rabbits to create an immune response. Serum was collected from the rabbits that was...

Published: 10/28/2024 | Inventor(s): Michael Bemben, John Badger, Katherine Roche

Keywords(s): 1, 4, ANTIBODY, Development, Listed LPM Contreras as of 4/15/2015, Neuroligin, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PThr707, THR739, VEXXXX, WBXXXX, WIXXXX, XAXXXX

Category(s): TherapeuticArea > Neurology, TherapeuticArea > Immunology, Application > Diagnostics, ResearchProducts > Antibodies, Application > Research Materials

Polyclonal and Monoclonal Antibodies to Human Eosinophil Major Basic Protein, Eosinophil Peroxidase, Eosinophil Cationic Protein, and Eosinophil-Derived Neurotoxin

Reagents particularly useful in configuring multiplex assays for simultaneous measurement and quantification of multiple eosinophil granule proteins and for immunohistochemistry. Ultimately these reagents may be used as diagnostics for many eosinophil-mediated disorders.

Published: 10/28/2024 | Inventor(s): Richard Davey, Thomas Nutman

Keywords(s): antibodies, BASIC, CATIONIC, EOSINOPHIL, Eosinophil-Derived, Eosionophil, Human, Listed LPM Fenn as of 4/15/2015, MAJOR, monoclonal, Neurotoxin, PEROXIDASE, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Protein, RM, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Rabbit Polyclonal Antibody to Detect a Pro-peptide Fragment of NSAID-activated Gene (NAG-1)/GDF15, a Protein Associated with Cancer

Chronic inflammation is clearly associated with an increase in the risk of cancer. Non-steroidal anti-inflammatory drugs (NSAIDs) are well documented as agents that inhibit tumor growth and with long-term use can prevent tumor development. NSAID-activated gene (NAG-1), a unique member of the TGF-beta superfamily, is highly induced by NSAIDs and numerous...

Published: 10/28/2024 | Inventor(s): Thomas Eling

Keywords(s): ANTIBODY, CC3AXX, CC3XXX, CCXXXX, CXXXXX, Detection, NAG-1/Gdf15, polyclonal, Pro-peptide, rabbit

Category(s): Collaboration Sought > Collaboration, Application > Research Materials, TherapeuticArea > Oncology

Cytochromes P450 CYP2J and CYP2C Polyclonal Antibodies and Recombinant Proteins

The National Institutes of Health announces polyclonal antibodies against mouse cytochrome P450s CYP2J and CYP2C. Cytochrome P450s catalyze the metabolism of a wide range of exogenous compounds, including drugs, industrial chemicals, environmental pollutants, and carcinogens. The 2C family of cytochrome P450 metabolizes an extensive number of drugs...

Published: 10/28/2024 | Inventor(s): Darryl Zeldin

Keywords(s): antibodies, CYP2C, CYP2J, CYTOCHROMES, IDXXXX, IXXXXX, P450, polyclonal, proteins, recombinant

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, Application > Research Materials, Application > Diagnostics

Chicken Polyclonal Antiserum to the Nitrone Spin Trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO)

Biological radicals resulted from oxidative stress has been implicated in human diseases, such as cancer and aging. There is, however, a paucity of reliable methods for in vivo or ex vivo detection of either radical formation, the end-products of radical formation or susceptibility for radical formation. The chicken polyclonal anti-DMPO can be used...

Published: 10/28/2024 | Inventor(s): Marilyn (Estate of) Ehrenshaft, Ronald Mason

Keywords(s): 5, 5-dimethyl-1-pyrroline, Antiserum, chicken, DMPO, Listed LPM Vepa as of 4/15/2015, Nitrone, N-oxide, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, SPIN, TRAP, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Aquaporin 2 Polyclonal Antibodies

Aquaporins, also known as water channels, form pores in cell membranes and selectively transport water in and out of the cell. Aquaporins are involved in regulation of water balance and blood pressure, and thirteen different isoforms have been found in mammals. Aquaporin 2 (AQP2) is located in the collecting duct of the kidney, and is regulated by...

Published: 10/28/2024 | Inventor(s): Mark Knepper

Keywords(s): Anti-Aquaporin, antibodies, ANTIBODY, AQUAPORIN, DIABETES, diabetes insipidus, IDXXXX, IXXXXX, KIDNEY, Nephrogenic diabetes insipidus, polyclonal, polyclonal antibodies, UAXXXX, WATER, water channel

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, TherapeuticArea > Rare / Neglected Diseases, Application > Research Materials, Application > Diagnostics, Application > Therapeutics

Rabbit Polyclonal Antiserum to the Nitrone Spin Trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO)

Published: 10/28/2024 | Inventor(s): Marilyn (Estate of) Ehrenshaft, Ronald Mason

Keywords(s): 5, 5-dimethyl-1-pyrroline, Antiserum, DMPO, Listed LPM Vepa as of 4/15/2015, Nitrone, N-oxide, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, rabbit, SPIN, TRAP, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Antibodies that Selectively Detect the Human Nestin Protein

Nestin is an intermediate filament protein first described in early embryonic neuroepithelial stem cells. Although not found in most cells of the mature CNS, nestin is the predominant marker used to detect the small population of undifferentiated cells. The presence of nestin identifies stem, progenitor and some tumor cells in the CNS, and also labels...

Published: 10/28/2024 | Inventor(s): Conrad Messam, Eugene Major, Jean Hou

Keywords(s): Antisera, Cross, Human, Listed LPM Maddox as of 4/15/2015, Nestin, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, R1XXXX, rabbit, Reactive, Rodent, RXXXXX, Specific, X

Category(s): Collaboration Sought > Licensing, Application > Research Materials

Rabbit Antisera to Various Matrix, Matricellular, and Other Secreted Proteins

The extracellular matrix (ECM) is composed of a group of proteins that regulate many cellular functions, such as cell shape, adhesion, migration, proliferation, and differentiation. Deregulation of ECM protein production or function contributes to many pathological conditions, including asthma, chronic obstructive pulmonary disease, arthrosclerosis,...

Published: 10/28/2024 | Inventor(s): Larry Fisher

Keywords(s): ANIMAL, Antisera, Human, Listed LPM Maddox as of 4/15/2015, Matricellular, MATRIX, polyclonal, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, proteins, rabbit, RXXXXX, SECRETED, VARIOUS, VAXXXX, VCXXXX, VDXXXX, VGXXXX, VIXXXX, WIXXXX, XAXXXX, XCXXXX, YAXXXX

Category(s): TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, TherapeuticArea > Oncology, ResearchProducts > Antibodies, Application > Research Materials, TherapeuticArea > Immunology, TherapeuticArea > Geriatrics, Application > Diagnostics