Search Results - research+reagent

24 Results Sort By:
WR (Western Reserve) Strain of Vaccinia Virus with K151E Mutation in A34R Gene
Mutation in gene A34R can regulate the release of progeny virions from the surface of parental cells.
Published: 7/25/2024   |   Inventor(s): Rafael Blasco, Bernard Moss
Keywords(s): A34, AC4XXX, AC5XXX, ACXXXX, AXXXXX, Cell, DDXXXX, DISSOCIATION, DXXXXX, GCXXXX, GLYCOPROTEIN, MEMBRANE, Progeny, REGULATED, research, RESEARCH MATERIAL, research reagent, RESEARCH TOOL, RM, RXXXXX, vaccinia, viral, virus, WIXXXX, XEXXXX, XKXXXX
Category(s): Collaboration Sought > Licensing, Application > Vaccines, Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease
Immortalized Stria Vascularis Cell Line SV-k1
Available for nonexclusive licensing for research uses is the cell line, SV-k1, derived from the Organ of Corti. The line was developed from the stria vascularis, an organ localized on the lateral wall of the cochlea, adjacent to the Organ of Corti, containing cell populations specialized in the production of an endolymph very rich in K+ characteristic...
Published: 7/25/2024   |   Inventor(s): Federico Kalinec, Gilda Canseco De Kalinec
Keywords(s): ID1XXX, IDXXXX, immortalized, RESEARCH MATERIAL, research reagent, RESEARCH TOOL, Stria, SV-k1, Vascularis, VPXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Ophthalmology, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Dental
USP22 Inhibitors for Cancer Therapeutics and Anti-tumor Immunity
NU 2021-018 INVENTORS Deyu Fang* Elena Montauti Ming Yan Beixue Gao SHORT DESCRIPTION Small molecule inhibitors of ubiquitin specific protease 22 that demonstrate antitumor activity and enhancement of the immune system in preclinical models BACKGROUND Tumors can create a highly immunosuppressive tumor microenvironment (TME) that favors...
Published: 7/25/2024   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Drug discovery, Research reagent, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics
A Self- Assembling of Large & Small Molecules into Ordered Macroscopic Structures
NU 2007-009InventorsHelena AzevedoRamille ShahSamuel Stupp*Short DescriptionSelf-sealing macroscopic sacs and membranes at the interface between two aqueous solutionsAbstractThe organization of molecules at interfaces is of great importance in the preparation of chemically defined surfaces and ordered materials. This invention provides self-assembly...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Biomedical, Diagnostics, Drug delivery, Materials, Research reagent, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Photocontrolled Dynamic Covalent Linkers for Polymer Networks
NU 2018-066INVENTORSJulia Kalow*Joseph AccardoBoyeong KangSHORT DESCRIPTIONDynamic crosslinkers that offer reversible stiffening and softening of polymer networks by a photoswitch BACKGROUNDPolymer networks can be linked by weak, reversible physical interactions or strong but irreversible covalent bonds. Dynamic covalent bonds enables strong and reversible...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Drug delivery, Materials, Polymer, Research reagent
Category(s): Physical Sciences > Materials and Industrial Processes
A Novel Class of Zinc-Chelating Ratiometric Fluorescent Probes
NU 2003-054 Inventors Masayasu Taki Thomas O'Halloran* AbstractNorthwestern scientists have synthesized a new class of zinc-chelating probes that are useful as ratiometric probes for zinc (Zn(II)). These reagents incorporate 2-(2'-hydroxypheny) benzooxazole (HBO) as a fluorophore with an aminomethyl pyridine moiety, to bind heavy metal ions selectively....
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Diagnostics, Research reagent, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Ultrasensitive Fluorescent Biosensors for Zinc
NU 2012-160 InventorsEmily Que Theresa Woodruff* Thomas O'Halloran* Short DescriptionNovel chemical sensor for zinc that can be used to monitor this ion in cells and the extracellular environment AbstractResearchers from Northwestern University have developed a new class of fluorescent zinc sensors, called ZincBYs, which can detect nanomolar concentrations...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Research reagent, Research tool, Sensors
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Bacterial Plasmid Encoding a GST-THAP11 (aa132-313) Fusion Protein for Research
NU 2012-155 Inventors Debabrata Chakravarti* John Brandon Parker Santanu Palchaudhuri Abstract Thanatos-associated protein (THAP) contains an atypical zinc finger motif with sequence-specific DNA-binding activity. Emerging data suggest that THAP proteins may function in chromatin-dependent processes, including transcriptional regulation. The...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Research reagent, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
A Mouse Model to Visualize Motor Neurons
NU 2012-053 Inventor Pembe Hande Ozlinder AbstractNorthwestern researchers have developed a novel mice model that enables the visualization of both corticospinal and spinal motor neurons. In addition to enabling the in vivo visualization of these neurons at different stages of motor neuron disorders, this method also provides the capability to isolate...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Animal Model, Cell Line, Research reagent
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Nanoparticle-Based Reagent for DNA and mRNA Detection
NU 2014-071 InventorsChad Mirkin* Chad Shade Robert Kennedy Short DescriptionNovel, highly sensitive reagent for detection of double stranded DNA in living cells AbstractNorthwestern scientists have developed a new reagent for detection of double stranded DNA in cells based on the well-known ruthenium DNA intercalator. Detection of specific genetic...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Devices, Health IT, Medical device, Nanoparticle, Research reagent
Category(s): Life Sciences > Healthcare Devices, Tools & IT
1 2 3