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The Y161F Substitution of Hemagglutinin Increases Antigenic Thermostability and Improves Yields of Influenza A Viruses
Background Vaccination has been the most efficient and economical strategy for preventing influenza virus infection and controlling disease spread among hosts. A high yield vaccine seed strain is required for timely vaccine manufacture and is thus a critical component of a successful influenza vaccination program. Unfortunately, it is not uncommon...
Published: 9/6/2024   |   Inventor(s): Xiu-Feng (Henry) Wan, Feng Wen
Keywords(s): Biomedical, Human Health, Pharma, Research, Veterinary Medicine
Category(s): Biotechnology, Biomedical, Pharma, Veterinary Medicine
Reagents, Devices, and Accessories for Kinetic Fluorogenic Chemical Quantification
Background Kinetic chromogenic (CG) and fluorogenic (FG) quantification deduces analyte concentration based on the reaction rate between the CG/FG probe and its targeted molecule. Little progress has been made in the past half century in either the theory or the applications of the kinetic spectroscopic quantification methods. Current kinetic CG/FG...
Published: 9/6/2024   |   Inventor(s): Dongmao Zhang, Max Wamsley
Keywords(s): Biomedical, Chemicals, Food, Instruments, Materials, Military or Defense, Research
Category(s): Biomedical, Materials, Instruments, Biotechnology, Agriculture & Food Science
WR (Western Reserve) Strain of Vaccinia Virus with K151E Mutation in A34R Gene
Mutation in gene A34R can regulate the release of progeny virions from the surface of parental cells.
Published: 7/25/2024   |   Inventor(s): Rafael Blasco, Bernard Moss
Keywords(s): A34, AC4XXX, AC5XXX, ACXXXX, AXXXXX, Cell, DDXXXX, DISSOCIATION, DXXXXX, GCXXXX, GLYCOPROTEIN, MEMBRANE, Progeny, REGULATED, research, RESEARCH MATERIAL, research reagent, RESEARCH TOOL, RM, RXXXXX, vaccinia, viral, virus, WIXXXX, XEXXXX, XKXXXX
Category(s): Collaboration Sought > Licensing, Application > Vaccines, Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease
Improved Acoustic Plethysmograph System for Noninvasive Measurement of Pulmonary Function
CDC researchers have developed a novel acoustic whole body plethysmograph (AWBP) that allows measurement of tidal volume in lab animals, independent of gas compression in the lung. This system provides particular advantages over the traditional whole body plethysmograph (WBP) when measuring model animals with increased gas compression due to increased...
Published: 7/25/2024   |   Inventor(s): David Frazer, Jeffrey Reynolds
Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC1XXX, AC2XXX, AC3XXX, AC6XXX, Acoustic, ACXXXX, ADXXXX, AE1BXX, AE1XXX, AE3XXX, AE4XXX, AEXXXX, ANIMAL, Animal Model, ANIMAL welfare, ASTHMA, Breath, BREATHING, CDC Docket Import, CDC Docket Import CDC Prosecuting, DDXXXX, DEVICE, DEXXXX, DXXXXX, FUNCTION, IA3XXX, IA5XXX, ICXXXX, IDXXXX, LUNG, lung cancer, Lung Disease, LUNGS, Lung-Targeted, Measuring, NIOSH, NIOSH-HELD, Plethysmograph, Pulmonary, Pulmonary edema, PULMONARY FIBROSIS, research, RESEARCH TOOL, RESPIRABLE, Respiration, respiratory, Respiratory Diseases, respiratory INFECTION, Tool, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XHXXXX, XIXXXX, XJXXXX, YCXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, TherapeuticArea > Pulmonology, TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Vaccines, Application > Therapeutics, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, ResearchProducts > Computational models/software, TherapeuticArea > Oncology
A method for energy-efficient and simultaneous nitrogen removal from wastewater and desalination of saline water
­A method for energy-efficient and simultaneous nitrogen removal from wastewater and desalination of saline water Partial nitration combined with anaerobic ammonium oxidation (anammox process) Background Annamox is a fully autotrophic anaerobic ammonium oxidation process with nitrate as an electron acceptor and fixed carbon from CO2 as a carbon...
Published: 8/15/2023   |   Inventor(s): Veera Gnaneswar Gude, Umesh Ghimire
Keywords(s): Agriculture, Aquaculture, Energy & Environmental, Research, Water Treatment
Category(s): Biotechnology
Antibodies and ELISA for Chondroitinase ABC
ELISA Determines ChABC Distribution and Content in Tissues and Bodily FluidsChondroitinase ABC (ChABC) is a bacterial enzyme that degrades sugar chains attached to the core protein of chondroitin sulfate proteoglycans (CSPGs). CSPGs are involved in a variety of biological processes in higher organisms, including humans. ChABC has a well-known potential...
Published: 7/12/2022   |   Inventor(s): David Muir
Keywords(s): Antibody, Chondroitinase, Hybridoma, Immunochemistry, Monoclonal, Monoclonal Antibody, Research
Category(s): Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others