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Reagents, Devices, and Accessories for Kinetic Fluorogenic Chemical Quantification

Background Kinetic chromogenic (CG) and fluorogenic (FG) quantification deduces analyte concentration based on the reaction rate between the CG/FG probe and its targeted molecule. Little progress has been made in the past half century in either the theory or the applications of the kinetic spectroscopic quantification methods. Current kinetic CG/FG...

Published: 4/1/2026 | Updated: 9/6/2024 | Inventor(s): Dongmao Zhang, Max Wamsley

Keywords(s): Biomedical, Chemicals, Food, Instruments, Materials, Military or Defense, Research

Category(s): Biomedical, Materials, Instruments, Biotechnology, Agriculture & Food Science

A Power Mapping and Modeling System for Integrated Circuits

Overview One of the biggest challenges for computer chip architects is figuring out the power supply and power distribution, because this limits the performance and reliability of semiconductor-based chips. However, the complex nature of modern multi-core processors, in addition to the way that power usage varies dep-ending on workload, makes it exceedingly...

Published: 3/5/2025 | Updated: 6/6/2024 | Inventor(s): Sherief Reda, Abdullah Nowroz, Kapil Dev

Keywords(s):

Category(s): Semiconductors, Artificial Intelligence (AI), Machine Learning, Instruments

Novel Electrical Device to Dissociate Tissue Sections into Single Cells for Downstream Single-Cell Analysis

Overview Single-cell analysis is an important analytical tool for studying heterogeneous cellular populations, such as cancer tissues, where rare mutations can drive metastasis and treatment response outcome. A major limitation of the clinical translation of single-cell analysis is the difficulty of isolating single cells from complex tissues. Our...

Published: 4/22/2026 | Updated: 10/17/2022 | Inventor(s): Anubhav Tripathi, E. Celeste (Cel) Welch

Keywords(s):

Category(s): Instruments, Research Tools

Portable Osteometric Device

Portable Osteometric device Overview of technology A portable measuring device to that uses laser sensors with time-of-flight technology to measure human skeletal material, especially bone length. Background on technology Osteometric data gives biological anthropologists, human osteologists, bioarcheologists and forensic anthropologists...

Published: 11/12/2024 | Updated: 6/13/2022 | Inventor(s): Eric Anderson

Keywords(s):

Category(s): Sensors & Diagnostics, Instruments

Wire Tie Down

Overview of Technology A system for managing excess wires on a smart sock prototype for athlete and lab testing Background of technology This product is a component of a “smart sock” that can be used in lab and athletics testing. The product improves on previous wire management methods which involve a more centralized method handled...

Published: 7/1/2026 | Updated: 5/19/2022 | Inventor(s): John Middleton, Will Carroll, Erin Parker, Reuben Burch, John Ball

Keywords(s):

Category(s): Instruments

Reagents and Device for Scattering and On-resonance Fluorescence Detection

Reagents and Device for Scattering and On-Resonance Fluorescence Detection Overview of Technology Determine instrument polarization bias in detection of the polarized scattered, transmitted, and emitted lights. Background A set of fluorescent mixture samples for determination and validation of instrument polarization bias in detection of...

Published: 1/13/2023 | Updated: 3/28/2022 | Inventor(s): Dongmao Zhang

Keywords(s): Instruments

Category(s): Instruments

X-ray Imaging with Micron Resolution

Novel Scintillating Detectors for X-ray Imaging with Micron Resolution Overview An x-ray detector is only as good as its image resolution. Our technology, which uses coherent bundles of scintillating fibers, provides a substantial increase in resolution over existing x-ray detector technologies. Market Opportunity The usefulness of x-ray imaging’s...

Published: 10/31/2025 | Updated: 9/7/2021 | Inventor(s): Kenneth Breuer, Avilash Cramer, Christopher Bull, Paul Waltz, Ragiv Gupta, Theodore Morse

Keywords(s):

Category(s): Engineering and Sensors, Instruments

Method to Predict and Diagnose Seizures and Other Neurological Events (Case 2045)

Method to Predict and Diagnose Seizures and Other Neurological Events Overview Though epilepsy is a common neurological disorder, the medical community still struggles to define and understand seizures and related neurological events. Our method uses implanted microelectrode arrays to predict and detect neurological events—a crucial first step...

Published: 10/31/2025 | Updated: 2/3/2021 | Inventor(s): John Donoghue, Leigh Hochberg, Wilson Truccolo

Keywords(s):

Category(s): Diagnostics, Instruments, Neuroscience, Software

Optimized, Cost Effective X-Ray Imaging that Rivals MRI: X-Ray Spatial Frequency Heterodyne Imaging with Protein-Based “Nanobubble” Contrast Agents

Principal Investigator: Christoph Rose-Petruck, PhD, ProfessorDepartment of ChemistryBrown UniversityProvidence, RIBrief Description:Spatial Frequency Heterodyne Imaging (SFHI) is a novel x-ray scatter imaging technique that utilizes nanoparticle contrast agents. Previous studies on SFHI have utilized only metal nanoparticle contrast agents such as...

Published: 10/31/2025 | Updated: 4/8/2020 | Inventor(s): Christoph Rose-Petruck, Trevor Douglas, Danielle Rand, Masaki Uchida

Keywords(s):

Category(s): Diagnostics, Drug Delivery, Instruments, Nanotechnology, Oncology, Research Tools

Supergratings - Improved Detection and Processing of Optical Signals (Case 1466)

Principal Investigator:Jingming Xu, PhD, ProfessorSchool of EngineeringBrown UniversityProvidence, RIBrief Description:Gratings are optical devices used to achieve wavelength-dependent characteristics by means of optical interference effects. These wavelength-dependent optical characteristics can serve to reflect light of a specific wavelength while...

Published: 3/5/2025 | Updated: 2/6/2015 | Inventor(s): Daniel Levner, Martin Fay, Jingming Xu

Keywords(s):

Category(s): Devices, Engineering and Sensors, Instruments, Research Tools

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