Search Results - covid

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­IMMUNOGENIC CORONAVIRUS FUSION PROTEINS AND RELATED METHODS
­IMMUNOGENIC CORONAVIRUS FUSION PROTEINS AND RELATED METHODS Researchers at Stanford have developed fusion proteins as a novel vaccine strategy for SARS-CoV2. As the causative force of the COVID-19 pandemic, SARS-CoV2 caused massive sustained morbidity, mortality, and societal disruption worldwide. Though COVID-19 has largely transitioned from...
Published: 10/6/2023   |   Inventor(s): Peter Kim, Natalia Friedland, Mrinmoy Sanyal, Payton Weidenbacher
Keywords(s): Coronavirus, COVID, COVID-19, Infectious Disease, Vaccine
Category(s): Technology Classifications > Biology
RNASEH-Assisted Detection Assay for RNA
Abstract: Several viral epidemics – such as the epidemics caused by H1N1 influenza virus, human immunodeficiency virus (HIV), Ebola virus, Zika virus, severe acute respiratory syndrome (SARS) virus, Middle East respiratory syndrome (MERS) virus and SARS-CoV-2 – have profoundly impacted global human health. Early identification of infected and/or infectious...
Published: 8/14/2024   |   Inventor(s): G Esta Sterneck, Dipak Poria
Keywords(s): COVID, COVID-19, INFLUENZA, Poria, RNA, RNASEH, SARS-CoV2, Sterneck, Viral RNA
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration
Sensitive and Economic RNA Virus Detection Using a Novel RNA Preparation Method
Abstract: DNA or RNA-based diagnostic tests for infectious diseases are critical in modern medicine. The current gold standard for COVID-19 detection is testing SARS-CoV-2 viral RNA by quantitative reverse transcription Polymerase Chain Reaction (RT-qPCR). This method involves patient sample collection with a nasopharyngeal swab, storage of the swab...
Published: 4/8/2024   |   Inventor(s): Bin Guan, Robert Hufnagel
Keywords(s): Biomarker, Chelating Resin, Chelex Resin, COVID, COVID-19, DNA/RNA diagnostic test, Extraction-free Detection, Infectious Diseases, SARS-CoV-2, virus
Category(s): TherapeuticArea > Oncology, Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing
DEVELOPMENT AND VALIDATION OF A 2-GENE HOST-VIRAL TRANSCRIPTOMIC CLASSIFIER FOR ENHANCED COVID-19 DIAGNOSIS
DEVELOPMENT AND VALIDATION OF A 2-GENE HOST-VIRAL TRANSCRIPTOMIC CLASSIFIER FOR ENHANCED COVID-19 DIAGNOSIS Researchers at UCSF and CZ Biohub SF have developed a two gene host signature that detects COVID infection regardless of the causative viral variant. Though COVID-19 has largely transitioned from pandemic to endemic status, viral variants of...
Published: 5/18/2023   |   Inventor(s): Charles (Chaz) Langelier
Keywords(s): Classifier, COVID, Host Determinants, qPCR, SARS-CoV-2, Viral Diagnostics
Category(s): Technology Classifications > Biology
AI-based Covid-19 drug discovery
INV-20097 Background The speed and the disruptive nature of the COVID-19 pandemic have taken both public health and biomedical research by surprise, demanding the rapid deployment of new interventions and the development and testing of an effective cure and vaccine. Considering the compressed timescales, the traditional methodologies relying on...
Published: 9/10/2024   |   Inventor(s): Deisy Morselli Gysi, Albert-Laszlo Barabasi, Italo do Valle, Onur Varol, Xiao Gan, Asher Ameli, Joseph Loscalzo, Marinka Zitnik
Keywords(s): COVID
Category(s): Technology Classifications > 3. Computer Science > Software
Oligonucleotide-based therapeutics targeting COVID-19
Background Oligonucleotides (ONs) are a promising class of agents in the fight against a wide variety of diseases including cancers, neuropathies, and metabolic disorders. Despite decades of research results indicating widespread clinical success, the therapeutic use of ONs have yet to be realized, which is somewhat due to the bio-pharmaceutical difficulties...
Published: 9/10/2024   |   Inventor(s): Ke Zhang
Keywords(s): COVID
Category(s): -Sensors, Technology Classifications > 1. Life Science > Therapeutics
Man 1-2 Man-PEGylated Derivative as a Tool for in vitro and in vivo Dendritic Cell Targeting
INV-1151 Background The immune system (IS) has a delicate equilibrium between its cells. The most important cells of the IS are the B lymphocytes (BL), macrophages (MO), and dendritic cells (DC), so-called antigen presenting cells (APC). They are the key-linkers between the innate and the adaptive immunity, which is a crucial factor that will lead...
Published: 9/10/2024   |   Inventor(s): Vladimir Torchilin, Tatiana Levchenko, Juan Pappalardo, Stefano Salmaso, Micaela Toniutti
Keywords(s): Cancer, Chemistry, COVID, Drug Delivery, Genome, Health, Healthcare Innovation, Medical, Nanomedicine, Research Tool
Category(s): -Health, -Nanomedicine, -Cancer, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery