Search Results - gbm+-+glioblastoma

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STING Agonist 8803 for Blood-Brain Barrier Opening in Glioblastoma Treatment
SHORT DESCRIPTION Chemical compound that opens the blood-brain barrier to enhance delivery of therapeutics for treating glioblastoma. INVENTORS Amy Heimberger* Northwestern University Feinberg School of Medicine, Department of Neurological Surgery * Principal Investigator NU Tech ID: NU 2025-212 IP...
Published: 5/7/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Adjunct therapy, ALS - Amyotrophic Lateral Sclerosis, Animal Model, Autoimmune disease, Bladder cancer, Brain cancer, Breast cancer, Cancer Treatment, Cancer/Oncology, Cervical cancer, CNS - Central Nervous System, Colon cancer, Drug delivery, Endometrial cancer, Gastric cancer, GBM - Glioblastoma, Head and neck cancer, Immunology, Immunotherapy, Liver cancer, Lung cancer, MS - Multiple Sclerosis, Neurodegenerative disease, Neurologic disease, Ovarian cancer, Pancreatic cancer, PD - Parkinson's Disease, Prostate cancer, Repurposed Drugs, Research tool, Small molecule, Targeted therapy, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools
Covalent ATG4B Inhibitors for Treatment of Cancer
NU 2025-186 INVENTORS Karl Scheidt* Weinberg College of Arts and Sciences, Department of Chemistry Claire Trudeau Shiyuan Cheng SHORT DESCRIPTION The invention introduces a novel class of peptidyl covalent reversible ketoamide inhibitors designed to target the cysteine protease ATG4B. BACKGROUND Glioblastoma (GBM) is an aggressive...
Published: 5/13/2026   |   Updated: 10/28/2025   |   Inventor(s):  
Keywords(s): Autophagy, Brain cancer, Cancer/Oncology, GBM - Glioblastoma, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Methods for Enhancing GBM Treatment Through Inhibition of Autophagy Mediator ATG4B
NU 2019-106 INVENTORS Shi-Yuan Cheng* Feinberg School of Medicine, Department of Neurology Bo Hu Tianzhi Huang SHORT DESCRIPTION A novel autophagy inhibitor to enhance the efficiency of standard cancer treatments BACKGROUND Glioblastoma (GBM), an incurable, lethal disease, exhibits a poor 5-year survival rate. The usual treatment...
Published: 5/13/2026   |   Updated: 6/1/2023   |   Inventor(s):  
Keywords(s): Autophagy, Brain cancer, Cancer/Oncology, GBM - Glioblastoma, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics