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A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

Application of the Synchronization Modulation Technique of the Na/k Pumps in Treatment of Muscle Fatigue

Competitive Advantages Postpones or relieves muscle fatigue Could reduce recovery time in different diseases Reduces ATP consumption thus increases energy for muscle contraction Summary Muscle fatigue is an important public health problem for large population especially for the people with occupations of athlete, soldier, and heavy-duty...

Published: 7/11/2023 | Inventor(s): Wei Chen, Jason Mast, Pengfei Liang

Keywords(s): Pain Relief / Management, Wound and Tissue Healing

Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Chemistry

Autonomous Drone for railroad track inspection

Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...

Published: 3/15/2023 | Inventor(s): Yu Qian, Yi Wang, Chen Chen

Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation

Category(s): Engineering and Physical Sciences

Targeted Theranostic NanoToxin for Treating Metastatic and Drug-resistant Tumors

Application Magnetic theranostic nano-toxin for imaging and drug delivery applications in cancer therapy. Key Benefits Induces tumor cell death via a different biological mechanism, compared to current chemotherapeutics, to overcome drug resistance mechanisms in tumor cells. Delivers high levels of therapeutic agents into metastatic tumors, while...

Published: 7/30/2024 | Inventor(s): Lily Yang, Xiangxue Guo, Hui Mao, Wei Chen

Keywords(s): Drug Delivery, Imaging

Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Diagnostics, TechPub Algolia > Micro and Nanotechnology

2015-671 Underground Shafts for Hydrogen Storage

SummaryResearchers at UCLA have developed an underground drilled shaft concept for storage of hydrogen or other gases.BackgroundOne challenge in creating a hydrogen economy is developing hydrogen gas storage solutions. Increased interest has helped the global hydrogen storage market grow to $2.6 billion in 2016, and it is expected to reach over $5...

Published: 7/19/2023 | Inventor(s): Adrienne Lavine, Hossein Kavehpour, Dante Simonetti, Richard Wirz, Chen Chen, Gabriela Bran, Gopinath Warrier, Hamarz Aryafar, Jonathon Kennedy, Joshua Jordan, Keith Lovegrove

Keywords(s): Energy & Water

Category(s): Energy & Environment > Energy Generation > Solar, Energy & Environment > Energy Storage

Hybrid Plasmonic Platform for Directing and Controlling Nanostructure Growth

Low-Heat, Bottom-Up Approach Can Produce Metal, Polymer or Bio-Molecule Structures for Catalysis, Biosensors, Electronic Devices and MoreThis surface plasmon mediated chemical solution deposition method uses surface plasmon resonance to deposit nanoparticles in the liquid phase at room temperature to direct and control nanostructure growth. Plasmonic...

Published: 6/27/2021 | Inventor(s): Wei Wei, Jingjing Qiu

Keywords(s): Catalysts, nanoparticle synthesis, Plasmonic, Thin Films

Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Materials

Fluorescent probes for the detection of hydrogen polysulfides

AbstractEndogenous hydrogen polysulfides have recently been recognized as important regulators in sulfur-related redox biology. H2Sn can activate tumor suppressors, ion channels, and transcription factors with higher potency than H2Sn. But, a major hurdle in this field is the lack of reliable and convenient methods of H2Sn detection. Researchers at...

Published: 10/8/2024 | Inventor(s): Ming Xian, Wei Chen

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Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Health & Well-being > Biotechnology, Technologies > Health & Well-being > Diagnostics