Search Results - hongsheng+he

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Development of novel liver-targeting glucocorticoid prodrugs

This technology presents novel liver-targeting glucocorticoid prodrugs designed to improve the treatment of inflammatory liver diseases and sepsis with enhanced efficacy and reduced systemic side effects. Background: Inflammatory liver diseases and sepsis represent significant clinical challenges due to their complex immune responses and the difficulty...

Published: 6/12/2026 | Updated: 6/11/2026 | Inventor(s): Hong Lu, Juntao Luo, Dandan Guo

Keywords(s): glucocorticoid, inflammatory liver disease, liver-selective, nanoparticle, prodrug, sepsis, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery

Early Detection for Pancreatic Cancer

Pancreatic cancer is highly lethal yet potentially treatable when detected at an early stage. However, early-stage disease remains notoriously difficult to identify. Dr. Sheng Pan at UTHealth, in collaboration with colleagues, has developed a blood-based proteomic assay designed to enhance pancreatic cancer screening approaches. This technology holds...

Published: 6/10/2026 | Updated: 6/10/2026 | Inventor(s): Sheng Pan

Keywords(s):

Category(s): Biomarkers, Diagnostics, Oncology

A Wearable, Waveguide-Integrated Optical System for Measuring Accommodation Changes in the Human Eye

This invention uses a waveguide as an optical combiner to integrate illumination, fixation, and imaging optics into a compact form factor to create a wearable, lightweight optical system for measuring accommodation changes in the human eye. By measuring the relative shift of the extracted beams, the system delivers a direct and highly sensitive way...

Published: 5/7/2026 | Updated: 5/7/2026 | Inventor(s): Hong Hua, Pengyinjie Lyu

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Displays, Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Imaging & Optics > Ophthalmology

A Wearable, Lightguide-Integrated Optical System of Wavefront Sensor for Measuring Aberration in the Human Eye

This invention uses a lightguide as an optical combiner to integrate illumination, fixation, and imaging optics into a single platform and create a wearable, lightweight optical system for measuring optical aberrations in the human eye. By using diffractive or geometric couplers, the invention allows ocular wavefronts to be measured at the same time...

Published: 5/7/2026 | Updated: 5/7/2026 | Inventor(s): Hong Hua, Pengyinjie Lyu

Keywords(s):

UWB-PostureGuard: A Privacy-Preserving RF Sensing System for Continuous Ergonomic Sitting Posture Monitoring

UWB-PostureGuard is an ergonomic posture monitoring technology that continuously detects sitting posture without cameras or wearable devices, while preserving user privacy. The technology is designed for real-time use in everyday desk and seated work environments, providing posture awareness and enabling timely feedback when sustained or potentially...

Published: 4/28/2026 | Updated: 4/28/2026 | Inventor(s): Haotang Li, Zhenyu Qi, Sen He, Kebin Peng, Sheng Tan, Yili Ren, Tomas Cerny, Jiyue Zhao, Zi Wang

Keywords(s):

Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Human Machine Interface, Technology Classifications > Healthcare Portfolios, Technology Classifications > Imaging & Optics > Sensors and Detection > Remote Sensing

Dual-Path Optical Measurement System with Integrated Pupil and FOV Scanning

This technology is a compact optical measurement system designed to test and evaluate head-mounted displays used in augmented, virtual, and mixed reality. The system captures both wide field-of-view images and fine image detail at the same time by splitting light into two coordinated measurement paths. A shared entrance pupil and integrated scanning...

Published: 4/20/2026 | Updated: 4/20/2026 | Inventor(s): Hong Hua, Pengyinjie Lyu

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Displays, Technology Classifications > Imaging & Optics > Lens & System Design

Dynamically Foveated Head-Mounted Displays with High Resolution Inset Image Based on Micro Lens Array

This technology is a head-mounted display architecture that provides high visual detail where the eye is looking, while maintaining a wide field of view for peripheral awareness. By using optical image duplication and selection to shift the high-resolution region across the display area as viewing direction changes, the system creates a small, high-resolution...

Published: 4/20/2026 | Updated: 4/20/2026 | Inventor(s): Hong Hua, Pengyinjie Lyu

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Displays, Technology Classifications > Imaging & Optics > Lens & System Design

A novel synthetic constitutive-active glucocorticoid receptor

Introducing "superGR," a novel synthetic glucocorticoid receptor fusion protein designed to enhance glucocorticoid therapy by providing ligand-independent activation and improved gene regulation for inflammatory diseases. Background: Glucocorticoids are widely used to treat inflammatory conditions like severe alcoholic hepatitis and sepsis,...

Published: 3/9/2026 | Updated: 2/19/2026 | Inventor(s): Hong Lu, Conor Fahy

Keywords(s): gene therapy, glucocorticoid, inflammatory liver disease, lung injury, sepsis, synthetic materials, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering

Human-Robot Teaming System

The Problem: Modern manufacturing and automation demand increasingly sophisticated human-robot collaboration requiring technologies that enhance human oversight and interaction with robotic systems, particularly in environments requiring meticulous quality control and error reduction. Current approaches in human-robot interaction face limitations,...

Published: 8/4/2025 | Updated: 8/4/2025 | Inventor(s): Hongsheng He

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Manufacturing, Technology Classifications > Systems & Services

Dynamically Controlled Pupil Steering Method for Enhanced Light Efficiency in Head-Mounted Displays

This is a programmable backlight display for head-mounted displays (HMDs) that dynamically steers light to the viewer’s pupil based on real-time eye tracking. This method reduces power consumption by illuminating only the necessary region corresponding to the pupil location while also improving brightness uniformity and efficiency. It also helps...

Published: 9/3/2025 | Updated: 8/4/2025 | Inventor(s): Hong Hua, Pengyinjie Lyu

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Displays, Technology Classifications > Imaging & Optics > Lens & System Design

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