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Combination Therapy to Treat Viral Acute Respiratory Distress Syndrome (ARDS)
­Advantages: PG’s anti-inflammatory effects mitigate viral inflammation of COVID-19. Intranasally administered mesenchymal stem cells (MSCs) create an anti-inflammatory microenvironment and can enhance neuro-regenerative effects. Targets viral transmission and neuronal damage to reduce virus-induced neuronal damage, and mortality, and...
Published: 7/15/2024   |   Inventor(s): Subhra Mohapatra, Shyam Mohapatra, Mahasweta Das, Andrew McGill, Karthick Mayilsamy
Keywords(s): Covid-19, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Respiratory
Methods for Treating Covid-19 Based on Individual Genomic Profiles
­Advantages: A high-throughput method offers a rapid and efficient way to predict severe outcomes in COVID-19 patients, facilitating faster clinical decision-making for pulmonary injury. Can be integrated with clinical variables to improve triage across healthcare settings, potentially reducing hospital stays, and optimizing resource allocation...
Published: 7/16/2024   |   Inventor(s): Jose Herazo-Maya, Brenda Juan-Guardela, Gaetane Michaud
Keywords(s):  
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics
AI-Driven Magnetic Respiratory Sensor for Real-Time Monitoring of Respiratory Diseases Like COVID-19
­Advantages: An AI-assisted contactless device that measures a patient’s breathing pattern and provides early and rapid detection of COVID-19 respiratory symptoms, in under 5 minutes. The ultrahigh sensitivity enables real-time monitoring of abnormal variations in a patient’s breath across multiple stages of disease. The portable...
Published: 7/15/2024   |   Inventor(s): Manh-Huong Phan, Kee Young Hwang, Valery Ortiz Jimenez, Baleeswaraiah Muchharla
Keywords(s): Artificial Intelligence, Medical Diagnostics, Respiratory Diseases
Category(s): Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Respiratory
Genistein For Asthma Prevention And Treatment
­Advantages: The research focuses on a tailored approach for managing asthma, specifically on individuals with high PAI-1 genotypes. The research underscores the therapeutic potential of genistein in mitigating asthma severity and associated complications. In vitro and animal data support the efficacy of genistein in reducing allergic inflammation...
Published: 8/14/2024   |   Inventor(s): Seong Cho, Raj Kumar, Brett Anderson, Michael Kaytor
Keywords(s): Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Biotechnology
Soy Isoflavones For Asthma Prevention
­Advantages: This research identified specific genetic markers (PAI-1 polymorphisms) linked to a significant reduction in asthma risk with soy isoflavone treatment. The research incorporates soy isoflavones into asthma management, leveraging the nutritional benefits of this natural compound and a holistic dietary path to respiratory wellness....
Published: 1/4/2024   |   Inventor(s): Seong Cho, Raj Kumar
Keywords(s): Genetics, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Biotechnology, Technology Classifications > Electronics > Food Sciences
New natural product scaffolds with activity against respiratory syncytial virus from the Antarctic Sponge Suberites sp.
­Advantages: This research introduces a novel class of compounds, including neosuberitenone, which demonstrates selectivity against respiratory syncytial virus (RSV). The research's focus on small molecules derived from a natural source, the Antarctic sponge Suberites sp., hints at the potential for cost-effective treatments. The identified...
Published: 3/20/2024   |   Inventor(s): Bill Baker, Joe Bracegirdle, Stine Olsen, Michael Teng, Kim Tran, Charles Amsler, James McClintock
Keywords(s): Antiviral Therapeutics, Infectious Diseases Treatment, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Infectious Diseases
A Liposomal Nanoformulation Encapsulating Linolenic Acid and Acetate Inhibits SARS-CoV-2 Infection
­Advantages: This research offers the potential to combat SARS-CoV-2 and respiratory viruses such as RSV and other coronaviruses. The research addresses various issues of the disease by targeting both the host and viral factors, including reduction in viral replication dampening the excessive immune response. The development of nanoformulations...
Published: 12/20/2023   |   Inventor(s): Andrew McGill, Subhra Mohapatra, Shyam Mohapatra, Eleni Markoutsa, Karthick Mayilsamy
Keywords(s): Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Medical Nanotechnology
Biomarker for Chronic Lung Disease: N-Myc-Interactor (NMI)
Competitive Advantages NMI Diagnostic Biomarker: predicting chronic lung allograft dysfunction (CLAD) in lung transplant patients NMI as a novel therapeutic target, to increase its expression in chronic lung disease Summary Lung transplant remains the primary treatment option for patients with advanced lung disease or irreversible pulmonary failure....
Published: 5/20/2024   |   Inventor(s): Nirmal Sharma, Mudassir Banday, Andreas Seyfang
Keywords(s): Biomarker, Cancer Treatment Lung Cancer, Medical Diagnostics, Medical Therapeutics Gene Therapy, Therapeutics
Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical
Lung Microbiome Isolation and Cultivation
­Competitive Advantages: Novel method to isolate, cultivate, and amplify the lung microbiome from a limited resource Beneficial for testing antibiotic sensitivity and drug resistance Enables lung microbiome transplantation for treatment of various chronic lung diseases Summary: Chronic lung diseases such as asthma, COPD, cystic fibrosis,...
Published: 9/3/2024   |   Inventor(s): Andreas Seyfang, Nirmal Sharma
Keywords(s): Cancer Treatment Lung Cancer, Health Tech, Microbiome
Category(s): Technology Classifications > Medical > Respiratory
Protein Palmiotylation Inhibitors of SARS Viruses
­Competitive Advantages Novel treatment for Covid-19 Inhibits palmitoylation of SARS-CoV-2 spike proteins resulting in reduced virus infectivity Inhibits syncytia formation Summary The last two decades have seen the emergence of three major corona virus(CoV) outbreaks. The SARS-CoV-2 spike glycoprotein (S) is a 1273 amino acids type I membrane...
Published: 8/8/2024   |   Inventor(s): Robert Deschenes, Arunava Roy, Ahmed Ramadan, Subhra Mohapatra, Marcello Giulianotti
Keywords(s): Cell & Tissue Culture & Engineering, Covid-19, Respiratory Diseases, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Respiratory
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