Search Results - neuron

6 Results Sort By:
NRN-EZ: An application to streamline biophysical modeling of synaptic integration using NEURON
NRN-EZ is an interactive application that allows NEURON users without extensive programming experience to define complex patterns of synaptic input activation. Background: Modeling software programs such as NEURON are widely used in the neuroscience community to address a broad range of research questions, including how neurons integrate synaptic...
Published: 9/5/2024   |   Inventor(s): Annalisa Scimemi, Evan Cobb
Keywords(s): neuron, software, synapic integration, synapse, Technologies
Category(s): Technology Classifications > Information Technology, Campus > University at Albany, Technology Classifications > Education and Training, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biomedical Science and Engineering
MANIPULATING SPATIAL RNA LOCALIZATION
­MANIPULATING SPATIAL RNA LOCALIZATION Researchers at Stanford have developed an inducible and programmable CRISPR-mediated transcript organization (CRISPR-TO) method for repositioning RNAs to various desired subcellular compartments. Spatial RNA transcriptomics, including subcellular mRNA localization, is a core mechanism for spatiotemporal regulation...
Published: 2/14/2024   |   Inventor(s): Lei Qi, Mengting Han
Keywords(s): Localization, mRNA, Neuron
Category(s): Technology Classifications > Biology
­COMPOUNDS AS GABA RECEPTOR MODULATORS
­COMPOUNDS AS GABA RECEPTOR MODULATORS Researchers at UCSF have developed novel GABA-modulating pharmaceutical compounds that are potential therapeutics for the treatment of chronic pain. Neurotransmitters are the building blocks of information transfer in the central nervous system and can modulate action potentials at the synapses of neurons...
Published: 12/5/2023   |   Inventor(s): Matthew McCarroll, Jason Sello, David Kokel, Allan Basbaum, Jarret Weinrich
Keywords(s): Inhibitor, Neuron, Pain
Category(s): Technology Classifications > Biology
­HUMAN CENTRAL NERVOUS SYSTEM (CNS) TARGETING AAV VARIANTS
­HUMAN CENTRAL NERVOUS SYSTEM (CNS) TARGETING AAV VARIANTS Researchers at UCSF and UC Berkeley have developed a recombinant adeno-associated virus (rAAV) with an altered capsid protein, where the rAAV exhibits greater ability to infect a central nervous system cell compared to wild-type AAVs. The central nervous system (CNS) comprises a multitude...
Published: 10/26/2023   |   Inventor(s): Tomasz Nowakowski, Galina Popava (Schmunk), David Schaffer, Danqing Zhu
Keywords(s): Adeno-associated Virus, Brain, Neuron
Category(s): Technology Classifications > Biology
METHODS FOR GENERATING PARVALBUMIN-POSITIVE INTERNEURONS
METHODS FOR GENERATING PARVALBUMIN-POSITIVE INTERNEURONS Researchers at UCSF and have developed a method for generating an enriched population of parvalbumin-positive interneurons. Parvalbumin-positive interneurons are the largest subpopulation of inhibitory interneurons in the cerebral cortex, and are involved in a variety of neurodevelopmental and...
Published: 5/18/2023   |   Inventor(s): Mohammed Mostajo-Radji, Alex Pollen
Keywords(s): Brain, Cortical, Interneurons, Neuron, Organoid, Parvalbumin-Positive
Category(s): Technology Classifications > Biology
2020-839 Endovascular Transvascular (Transmural) Neuromodulation Technique
SUMMARY: UCLA researchers in the Department of Neurosurgery have developed an endovascular method to deliver pharmaceutical agents with various physical properties (e.g. liquids, gels, solids) across the wall of a vessel directly to the nervous system tissue. BACKGROUND: Portions of the nervous system, such as the autonomic ganglia and associated...
Published: 7/19/2023   |   Inventor(s): Geoffrey Colby, Michael Dacey, Jeffrey Ardell
Keywords(s): Cardiovascular, Neurology, Neuromodulation, Neuron, Neurostimulation, Neurosurgery, Peripheral Vascular Disease
Category(s): Medical Devices > Neural Stimulation, Medical Devices > Surgical Tools