Search Results - jeffrey+ardell

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SYSTEM AND METHOD FOR IN VIVO DETECTION OF BIOMOLECULES IN TISSUES, ORGANS AND EXTRACELLUAR FLUID
Summary A minimally invasive electrochemical sensing platform that places tiny electrodes in or near target tissues (e.g., heart, nerves, vessels) to continuously detect specific biomolecules—including catecholamines and peptides—with high spatial and temporal resolution. This enables real-time physiologic monitoring and closed-loop therapies...
Published: 9/10/2025   |   Inventor(s): Kalyanam Shivkumar, Corey Smith, Jeffrey Ardell
Keywords(s):  
Category(s): Medical Devices, Life Science Research Tools, Life Science Research Tools > Research Methods
2020-839 Endovascular Transvascular (Transmural) Neuromodulation Technique
SUMMARY: UCLA researchers in the Department of Neurosurgery have developed an endovascular method to deliver pharmaceutical agents with various physical properties (e.g. liquids, gels, solids) across the wall of a vessel directly to the nervous system tissue. BACKGROUND: Portions of the nervous system, such as the autonomic ganglia and associated...
Published: 2/14/2025   |   Inventor(s): Geoffrey Colby, Michael Dacey, Jeffrey Ardell
Keywords(s): Cardiovascular, Neurology, Neuromodulation, Neuron, Neurostimulation, Neurosurgery, Peripheral Vascular Disease
Category(s): Medical Devices > Neural Stimulation, Medical Devices > Surgical Tools
2017-997 Neural Modulation of Autonomic Nervous System to Alter Memory and Plasticity of the Autonomic Network
SUMMARY: Researchers at UCLA from the Departments of Medicine and Bioengineering have created a device that modulates the autonomic nervous system to treat heart conditions like arrhythmias.BACKGROUND:The autonomic nervous system controls unconscious bodily functions like breathing and maintaining heart function. The cardiac autonomic nervous system...
Published: 7/17/2025   |   Inventor(s): Kalyanam Shivkumar, Marmar Vaseghi, Jeffrey Ardell
Keywords(s):  
Category(s): Medical Devices > Surgical Tools, Therapeutics > Cardiovascular
2018-375 SPATIO-TEMPORAL PACING AND RECORDING FOR EVALUATION, INDUCTION, AND MAPPING OF ARRHYTHMIAS
Spatio-Temporal Pacing and Recording for Evaluation, Induction, and Mapping of ArrhythmiasSUMMARYResearchers led by Marmar Vaseghi from the School of Medicine at UCLA have developed a high density electrode array to evaluate, induce, and map arrhythmias.BACKGROUNDCardiac arrhythmias are abnormal heartbeats that arise from malfunctions of electrical...
Published: 2/14/2025   |   Inventor(s): Marmar Vaseghi, Jeffrey Ardell, Kalyanam Shivkumar
Keywords(s): Cardiovascular, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Medical Devices and Materials, Monitoring And Recording Systems, Therapeutics & Vaccines
Category(s): Diagnostic Markers, Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics, Therapeutics > Cardiovascular
2015-792 Vagal Suppression of Neurally-Induced Atrial Fibrillation
Vagal Suppression Of Neurally-Induced Atrial FibrillationSUMMARYUCLA researchers in the Department of Cardiology have identified a novel mechanism for controlling atrial fibrillation via neuromodulation.BACKGROUNDAtrial fibrillation (AF), an abnormal heart beat characterized by rapid and irregular beating, affects more than 3 million people in the United...
Published: 7/17/2025   |   Inventor(s): Jeffrey Ardell, Kalyanam Shivkumar
Keywords(s): Cardiovascular, Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Cardiovascular