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Search Results - organoid
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Novel three-dimensional, conformal microelectrode arrays for interrogating and manipulating three-dimensional cell culture systems
A flexible, biocompatible microelectrode array wraps around 3D cell cultures such as
organoid
s, enabling comprehensive electrical recording and stimulation for advanced research, drug testing, and personalized medicine, overcoming the limitations of traditional flat electrode arrays. Background: Three-dimensional (3D) cell culture systems, such as...
Published: 1/26/2026
|
Inventor(s):
Susan Sharfstein
,
Nathaniel Cady
,
Yubing Xie
,
Natalya Tokranova
,
Anthony Manning
,
Fernando Pesantez Torres
Keywords(s):
3D culture
,
3D flexible microelectrode
,
electrophysiology
,
microelectrode array
,
microfabrication
,
neurodegeneration
,
organoid
,
polymer materials
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Biomedical Science and Engineering
3D PRINTING OF
ORGANOID
SLURRIES
3D PRINTING OF
ORGANOID
SLURRIES Researchers at Stanford have developed methods for 3D printing and post-biomanufacturing of organoid slurries in a high yield stress matrix. Biomanufactured tissues and organs on demand has been a long-standing challenge in the field of tissue engineering. Despite the advancements allowed by 3D bioprinting, current...
Published: 11/6/2024
|
Inventor(s):
Mark Syklyar-Scott
,
Jianyi Du
Keywords(s):
Bioink
,
Matrix
,
Organoid
,
Printing
Category(s):
Technology Classifications > Biology
HYDROGEL-ECM GRANULAR COMPOSITES WITH VISCOUS INTERSTITIUM
HYDROGEL-ECM GRANULAR COMPOSITES WITH VISCOUS INTERSTITIUM Researchers at UCSF and CZ Biohub San Francisco have developed methods for making and using yield-stress composite matrix formulations for
organoid
printing. Organoids are attractive models of health and disease as they recapture many important structural and physiological aspects of...
Published: 1/31/2025
|
Inventor(s):
Austin Graham
,
Zev Gartner
,
Rafael Gómez-Sjöberg
Keywords(s):
Bioprinting
,
Organoid
Category(s):
Technology Classifications > Biology
ARRAY PLATFORM FOR HIGH-THROUGHPUT
ORGANOID
PROFILING
ARRAY PLATFORM FOR HIGH-THROUGHPUT
ORGANOID
PROFILING Researchers at Stanford have developed a new methodology for image processing that allows for high-throughput characterization of organoid phenotypes. Organoids represent a major step forward in in vitro research studies into a myriad of disease states. 3D organoid models possess key advantages...
Published: 9/14/2023
|
Inventor(s):
Polly Fordyce
,
Christina Curtis
,
Alexandera Sockell
,
Wing Wong
Keywords(s):
CRISPR
,
High-Throughput
,
Imaging
,
Organoid
Category(s):
Technology Classifications > Biology
In vitro Generation of an Autologous Thymic
Organoid
from Human Pluripotent Stem Cells
Abstract: The thymus is an integral part of the adaptive immune system as it generates T cells. Its function diminishes rapidly as the body ages, leading to a compromise of the immune system in the elderly. Reconstitution of adaptive immunity through mass production of different T cell types is therefore a therapeutic need in immunocompromised populations....
Published: 4/22/2025
|
Inventor(s):
Raul Sakoda
,
Nicholas Restifo
Keywords(s):
Aging
,
IMMUNOCOMPROMISED
,
Immunotherapy
,
Natural Killer T Cells
,
NKT
,
Organogenesis
,
Organoid
,
Pluripotent Stem Cells
,
T Cells
,
THYMUS
,
Vizcardo
Category(s):
Application > Therapeutics
,
TherapeuticArea > Oncology
,
TherapeuticArea > Immunology
,
Collaboration Sought > Licensing
METHODS FOR GENERATING PARVALBUMIN-POSITIVE INTERNEURONS
METHODS FOR GENERATING PARVALBUMIN-POSITIVE INTERNEURONS Researchers at UCSF and have developed a method for generating an enriched population of parvalbumin-positive interneurons. Parvalbumin-positive interneurons are the largest subpopulation of inhibitory interneurons in the cerebral cortex, and are involved in a variety of neurodevelopmental and...
Published: 5/18/2023
|
Inventor(s):
Mohammed Mostajo-Radji
,
Alex Pollen
Keywords(s):
Brain
,
Cortical
,
Interneurons
,
Neuron
,
Organoid
,
Parvalbumin-Positive
Category(s):
Technology Classifications > Biology