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Search Results - organoid
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3D PRINTING OF
ORGANOID
SLURRIES
3D PRINTING OF
ORGANOID
SLURRIES Researchers at Stanford have developed methods for 3D printing and post-biomanufacturing of organoid slurries in a high yield stress matrix. Biomanufactured tissues and organs on demand has been a long-standing challenge in the field of tissue engineering. Despite the advancements allowed by 3D bioprinting, current...
Published: 11/6/2024
|
Inventor(s):
Mark Syklyar-Scott
,
Jianyi Du
Keywords(s):
Bioink
,
Matrix
,
Organoid
,
Printing
Category(s):
Technology Classifications > Biology
HYDROGEL-ECM GRANULAR COMPOSITES WITH VISCOUS INTERSTITIUM
HYDROGEL-ECM GRANULAR COMPOSITES WITH VISCOUS INTERSTITIUM Researchers at UCSF and CZ Biohub San Francisco have developed methods for making and using yield-stress composite matrix formulations for
organoid
printing. Organoids are attractive models of health and disease as they recapture many important structural and physiological aspects of...
Published: 6/6/2024
|
Inventor(s):
Austin Graham
,
Zev Gartner
,
Rafael Gomez-Sjoberg
Keywords(s):
Bioprinting
,
Organoid
Category(s):
Technology Classifications > Biology
ARRAY PLATFORM FOR HIGH-THROUGHPUT
ORGANOID
PROFILING
ARRAY PLATFORM FOR HIGH-THROUGHPUT
ORGANOID
PROFILING Researchers at Stanford have developed a new methodology for image processing that allows for high-throughput characterization of organoid phenotypes. Organoids represent a major step forward in in vitro research studies into a myriad of disease states. 3D organoid models possess key advantages...
Published: 9/14/2023
|
Inventor(s):
Polly Fordyce
,
Christina Curtis
,
Alexandera Sockell
,
Wing Wong
Keywords(s):
CRISPR
,
High-Throughput
,
Imaging
,
Organoid
Category(s):
Technology Classifications > Biology
In vitro Generation of an Autologous Thymic
Organoid
from Human Pluripotent Stem Cells
Abstract: The thymus is an integral part of the adaptive immune system as it generates T cells. Its function diminishes rapidly as the body ages, leading to a compromise of the immune system in the elderly. Reconstitution of adaptive immunity through mass production of different T cell types is therefore a therapeutic need in immunocompromised populations....
Published: 4/8/2024
|
Inventor(s):
Raul Sakoda
,
Nicholas Restifo
Keywords(s):
Aging
,
IMMUNOCOMPROMISED
,
Immunotherapy
,
Natural Killer T Cells
,
NKT
,
Organogenesis
,
Organoid
,
Pluripotent Stem Cells
,
T Cells
,
THYMUS
,
Vizcardo
Category(s):
Application > Therapeutics
,
TherapeuticArea > Oncology
,
TherapeuticArea > Immunology
,
Collaboration Sought > Licensing
Method for Assembling Decellularized Tissue Extracellular Matrix in 3D Tumor Spheroids
Abstract: Cell culture investigations using spheroids and
organoid
models have had a major impact on biomedical advancement as alternative sources for costly, in vivo animal testing. However, these 3-D cell constructs are limited in that they do not integrate extracellular components within the structure important for more reliable and accurate biological...
Published: 12/17/2024
|
Inventor(s):
Matthew Wolf
,
Michael Buckenmeyer
,
Elizabeth Brooks
Keywords(s):
ECM
,
extracellular matrix
,
Organoid
,
Scaffold
,
Spheroid
,
Wolf
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
Application > Research Materials
,
TherapeuticArea > Oncology
METHODS FOR GENERATING PARVALBUMIN-POSITIVE INTERNEURONS
METHODS FOR GENERATING PARVALBUMIN-POSITIVE INTERNEURONS Researchers at UCSF and have developed a method for generating an enriched population of parvalbumin-positive interneurons. Parvalbumin-positive interneurons are the largest subpopulation of inhibitory interneurons in the cerebral cortex, and are involved in a variety of neurodevelopmental and...
Published: 5/18/2023
|
Inventor(s):
Mohammed Mostajo-Radji
,
Alex Pollen
Keywords(s):
Brain
,
Cortical
,
Interneurons
,
Neuron
,
Organoid
,
Parvalbumin-Positive
Category(s):
Technology Classifications > Biology