Search Results - medical+pharmaceuticals

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Use of Chemokine Receptor Antagonists for Fluid Resuscitation
­Advantages: Reduces amount of fluid required for resuscitation Reduces risk of complications New direction in critical care Summary: Our research focuses on improving the treatment of critically ill patients, especially those undergoing major surgery or suffering from conditions like severe burns, trauma, hemorrhage, or sepsis. Adequate...
Published: 9/21/2023   |   Inventor(s): Anthony DeSantis, Xianlong Gao, Matthias Majetschak
Keywords(s): Critical Care / Trauma, Medical Pharmaceuticals, Therapeutics
Category(s): Technology Classifications > Medical
Neuronal suppression of FKBP51 expression by fatty acid derivatives to prevent mental disorders
­Advantages: The study highlights FKBP51 as a promising target for the treatment of disorders such as major depression, PTSD, anxiety disorders, and Alzheimer's disease. The research recognizes the influence of single nucleotide polymorphisms (SNPs) in the FKBP5 gene on FKBP51 levels and susceptibility to certain disorders. The researchers...
Published: 9/3/2024   |   Inventor(s): Charles Lockwood, Laura Blair, Ozlem Guzeloglu-Kayisli, Umit Kayisli
Keywords(s): Biotechnology, Medical Pharmaceuticals, Neurodegenerative Diseases, Therapeutics
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Therapeutics
Use of Auranofin for Treatment of Neurodegenerative Disorders
­Competitive Advantages Potential treatment for Alzheimer’s, FTD, and other neurodegenerative disorders Results show that various factors including insulin lead to activation of aPKC and the NFkappa-B inflammatory pathway in brain neurons and glial cells Auranofin (AF) is an FDA approved drug for other uses, thus relatively easy to conduct...
Published: 1/25/2024   |   Inventor(s): Robert Farese, Mini Sajan
Keywords(s): Medical Pharmaceuticals, Neurodegenerative Diseases, Neuroscience
Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Neuroscience
A Human Origin Probiotics- Lactobacillus Rhamnosus HL-200 to Reduce Leaky Gut by Metabolizing Ethanolamine
­Advantages Might be an effective treatment for leaky gut syndrome associated chronic inflammation. The novel probiotic induces ethanolamine metabolizing activity thus strengthening the gut barrier. Might help evade from several other diseases causes by leaky gut syndrome. Summary Leaky gut syndrome is a key source of chronic inflammation,...
Published: 5/16/2024   |   Inventor(s): Hariom Yadav, Shalini Jain, Sidharth Mishra
Keywords(s): Diabetes, Inflammatory Diseases, Medical Pharmaceuticals, Neurodegenerative Diseases
Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Therapeutics
Creation Of Split Tau Oligomerization Assay
Competitive Advantages Allows for live-cell measurement of tau oligomerization A valuable tool for investigating tau oligomer modifying drugs Summary Oligomeric tau species are crucial to induce tau transmission between neurons and toxicity within neurons. USF investigators established a novel technique to measure tau oligomierization via visualizing...
Published: 9/25/2023   |   Inventor(s): Daniel Lee, Chao Ma
Keywords(s): Medical Diagnostics, Medical Pharmaceuticals, Neuroscience
Category(s): Technology Classifications > Medical > Medical Diagnostics
Antimicrobials From an Epigenetics Based Fungal Metabolite Screening Program
USF researchers have identified five novel antimicrobial compounds applicable against several drug targets such as ESKAPE pathogens, Leishmania donovani, Mycobacterium tuberculosis (TB), Clostridium difficile, Naegleria fowleri, and cancer. These five compounds were isolated via a fungal metabolite screening program. Each compound exhibited specific bioactivity...
Published: 8/25/2023   |   Inventor(s): Bill Baker, Danielle Demers
Keywords(s): Medical Pharmaceuticals, Pharmaceuticals
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical
Hyaluronic acid coated nuccleotide/peptide NP for improved formulation, performance and molecular targeting
Competitive Advantages Improved ability to transfect desired cells Improved molecular targeting Improved efficacy Numerous applications in research and medicine Summary Researchers at USF have discovered a method to transfect cells more effectively using the peptide melittin. Melittin is an amphipathic peptide, allowing it to enter and disrupt...
Published: 7/17/2023   |   Inventor(s): Samuel Wickline, Hua Pan
Keywords(s): Biotechnology, Medical Pharmaceuticals, Medical Therapeutics Cell Therapy, Peptides
Category(s): Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications > Medical, Technology Classifications > Medical > Pharmaceuticals
A Zero-Restoring Force Reservoir for Fluidic Systems
Competitive Advantages Inexpensive Highly reliable Scalable pump rate Reduced fabrication complexity Summary Our inventors have developed peristaltic micro pumps that are fabricated with direct write printing technologies. The micro-pumps are fabricated such that they are scalable to a broad range of pump rates. These novel...
Published: 9/11/2023   |   Inventor(s): Farzad Forouzandeh, David Borkholder, Robert Frisina, Joseph Walton, Xiaoxia Zhu
Keywords(s): Health Tech, Industrial Applications, Mechanical Engineering, Medical Pharmaceuticals, Medical Pharmaceuticals Drug Delivery Systems
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical, Technology Classifications > Medical > Pharmaceuticals