Search Results - robert+frisina

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Targeting mTOR-Related Autophagy Dysfunction to Treat Age-Related Hearing Loss with Rapamycin and Its Derivatives
Advantages: Novel Application of FDA approved drugs, rapamycin and its derivatives, for treating age-related hearing loss (ARHL). Targeting mTOR alleviates oxidative stress and inflammation in the cochlea, enhancing cellular health and resilience to age-related damage. Potential to Reverse or Delay Age-related hearing loss (ARHL) in patients. Summary: Age-related...
Published: 11/5/2024   |   Inventor(s): Robert Frisina, Xiaohua Zhu, Bo Ding, Xiaoxia Zhu
Keywords(s): Pharmaceuticals, Therapeutics
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices
Molecular Imaging of the Cochlea
­Advantages: Microenvironment Sensitivity: Unveils subtle structural changes within the cochlear microenvironment, enhancing auditory health understanding. Treatment Response Tracking: Precisely quantifies potassium concentration changes, enabling accurate monitoring of treatment responses and disease progression. Non-Invasive Approach: Offers...
Published: 9/11/2024   |   Inventor(s): Parveen Bazard, Mikalai Budzevich, Xiaoxia Zhu, Bo Ding, Robert Frisina
Keywords(s): Diagnostics, Medical Imaging
Category(s): Technology Classifications > Medical > Medical Imaging, Technology Classifications > Medical > Medical Diagnostics
Hormone Treatment for Age-Related Hearing Loss-Presbycusis
­Competitive Advantages Utilizes natural and FDA-approved compounds Suitable for systemic applications Minimal side effects Summary Our researchers have developed a novel drug combination of FDA-approved compounds that achieve significant therapeutic effects in the treatment of ARHL. These compounds include aldosterone, ammonium chloride,...
Published: 8/20/2024   |   Inventor(s): Bo Ding, Joseph Walton, Xiaoxia Zhu, Robert Frisina
Keywords(s):  
Category(s): Technology Classifications > Medical > Pharmaceuticals
Plasmonic Stimulation of Electrically Excitable Biological Cells
Competitive Advantages Reduced/no tissue damage Improved spatiotemporal resolution Higher transduction fidelity Eliminates unwanted heating/stimulation that occurs with infrared stimulation Summary A novel technology has been developed to stimulate electrically active biological cells using visible light and metallic nanoparticles...
Published: 9/11/2023   |   Inventor(s): Joseph Walton, Parveen Bazard, Robert Frisina, Venkat Bhethanabotla
Keywords(s):  
Category(s): Technology Classifications > Electronics, Technology Classifications > Electronics > Nanotechnology
Flotation Device for Seizure Sufferers
Competitive Advantages: • Automatically detects seizures • False detection override option • Comfortable and non-bulky • Meets highest Coast Guard Personal Flotation Device regulations Summary Our inventors have developed a device capable of automatically detecting seizures via electromyography (EMG) signals from electrodes...
Published: 8/25/2023   |   Inventor(s): Christopher Passaglia, Evan Ticknor, Everett Rogers, Kyle Cogswell, Robert Frisina, Selina Guardiano, Timothy Jacobson, Aydin Sunol
Keywords(s): Devices for Disabilities / Rehabilitation
Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Medical Devices
A Zero-Restoring Force Reservoir for Fluidic Systems
Competitive Advantages Inexpensive Highly reliable Scalable pump rate Reduced fabrication complexity Summary Our inventors have developed peristaltic micro pumps that are fabricated with direct write printing technologies. The micro-pumps are fabricated such that they are scalable to a broad range of pump rates. These novel...
Published: 9/11/2023   |   Inventor(s): Farzad Forouzandeh, David Borkholder, Robert Frisina, Joseph Walton, Xiaoxia Zhu
Keywords(s): Health Tech, Industrial Applications, Mechanical Engineering, Medical Pharmaceuticals, Medical Pharmaceuticals Drug Delivery Systems
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical, Technology Classifications > Medical > Pharmaceuticals
Hybrid Electro-Plasmonic Modulation of Neural Activity with Visible-Light-Sensitive Gold Nanotransducer Interface
Competitive Advantages Better spatial resolution than standard electrical stimulation Capable of reducing electrical stimulation current input by 40% Specific point stimulation, reducing spread to surrounding tissue 3-fold higher success rate of nerve cell response compared to pure optical stimulation 5-fold better post-stimulation recovery/survival...
Published: 1/18/2024   |   Inventor(s): Ratka Damnjanovic, Parveen Bazard, Robert Frisina, Venkat Bhethanabotla
Keywords(s): Drug Delivery and Nanomedicine, Nanotechnology, Neuroscience
Category(s): Technology Classifications > Electronics, Technology Classifications > Electronics > Nanotechnology