Search Results - medical+therapeutics+cell+therapy

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New Device Material for a Flexible Chronic Implantable Neural Interface
­Advantages: Superior biocompatibility reduces immune responses. Excellent electrical conductivity enhances signal transmission. Exceptional mechanical strength enables durable and flexible probes. Summary: Implantable neural interfaces (INIs) are devices configured to connect with the human nervous system through electrical means. Such...
Published: 9/3/2024   |   Inventor(s): Stephen Saddow, Chenyin Feng, Christopher Frewin
Keywords(s): Drug Delivery and Nanomedicine, Medical Therapeutics Cell Therapy, Nanotechnology, Neurodegenerative Diseases
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biomaterials, Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience
RNA Aptamer Targeting of ADAM8 in the Tumor Microenvironment
­Advantages: Novel targeted RNA aptamers to inhibit ADAM8 and block cancer associated fibroblast maintenance in the tumor microenvironment. RNA aptamer benefits: high affinity, high specificity, and low immunogenicity Promising preclinical in vitro and in vivo outcomes Summary: This research delves into the intricate dynamics of cancer progression,...
Published: 5/20/2024   |   Inventor(s): Paul Kuo, Zhiyong Mi
Keywords(s): Cancer Treatment, Medical Therapeutics Cell Therapy, Medical Therapeutics Gene Therapy
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Oncology, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Cell & Tissue Engineering
Novel Bronchodilators For Treating Obstructive Lung Disease
­Competitive Advantages Identified novel bronchodilators agonists that relax airway smooth muscle Could be a novel therapeutic for asthma and other obstructive lung diseases Could also be a therapeutic for other types of bronchoconstriction caused by smoke or anaphylaxis Summary Currently patients with obstructive airways diseases have...
Published: 5/21/2024   |   Inventor(s): Stephen Liggett, James Leahy, Donghwa Kim, Steven An
Keywords(s): Medical Therapeutics Cell Therapy, Respiratory Diseases, Respiratory Diseases Treatment, Therapeutics
Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics
Ketone Bodies Multifaceted Anti-Aging/Pro-Longevity Therapeutic Effect
Competitive Advantages Provides anti-catabolic effects and metabolic regulation in atrophy mouse models Helps keep pro-aging hormone insulin and IGF-1 suppressed Viable longevity therapeutic across various disease and health environment Summary Aging is a complicated multi-factorial process for which intervention remain a scientific challenge....
Published: 6/11/2024   |   Inventor(s): Andrew Koutnik, Dominic D'Agostino
Keywords(s): Medical Therapeutics Cell Therapy, Therapeutics
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical
Hyaluronic acid coated nuccleotide/peptide NP for improved formulation, performance and molecular targeting
Competitive Advantages Improved ability to transfect desired cells Improved molecular targeting Improved efficacy Numerous applications in research and medicine Summary Researchers at USF have discovered a method to transfect cells more effectively using the peptide melittin. Melittin is an amphipathic peptide, allowing it to enter and disrupt...
Published: 7/17/2023   |   Inventor(s): Samuel Wickline, Hua Pan
Keywords(s): Biotechnology, Medical Pharmaceuticals, Medical Therapeutics Cell Therapy, Peptides
Category(s): Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications > Medical, Technology Classifications > Medical > Pharmaceuticals
Mithramycin A in Combination with Cancer Immunotherapy
Competitive Advantages Reformulated combination therapeutic allows for shorter clinical pathway Targets cancer stem cells and their ability to escape the immune system More effective at inhibiting tumor growth than either treatment alone Summary Our researchers have formulated a method to target cancer stem cells (CSCs) using Mithramycin...
Published: 9/25/2023   |   Inventor(s): Subhra Mohapatra, Shyam Mohapatra, Rinku Dutta, Quarni Waise
Keywords(s): Cancer Treatment, Medical Therapeutics Cell Therapy
Category(s): Technology Classifications > Cancer, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical