Search Results - matthias+majetschak

3 Results Sort By:
Chemokine Receptor CCR1 as a New Therapeutic Target to Improve Hemorrhagic Shock Resuscitation
Advantages Significant reduction in fluid requirements without noticeable adverse events Clinically tested compound for multiple sclerosis, demonstrating favorable safety and tolerability profile Mitigation of inflammation and tissue edema Broad market potential in major surgeries, sepsis, burn care, and military medicine, where fluid management...
Published: 8/18/2025   |   Inventor(s): Matthias Majetschak, Xianlong Gao, Elizabeth Cook
Keywords(s): Critical Care / Trauma, Surgery
Category(s): Technology Classifications > Medical > Surgery, Technology Classifications > Medical > Therapeutics
Use of Chemokine Receptor Antagonists for Fluid Resuscitation
­Advantages: Reduces amount of fluid required for resuscitation Reduces risk of complications New direction in critical care Summary: Our research focuses on improving the treatment of critically ill patients, especially those undergoing major surgery or suffering from conditions like severe burns, trauma, hemorrhage, or sepsis. Adequate...
Published: 9/21/2023   |   Inventor(s): Anthony DeSantis, Xianlong Gao, Matthias Majetschak
Keywords(s): Critical Care / Trauma, Medical Pharmaceuticals, Therapeutics
Category(s): Technology Classifications > Medical
Heteromers Between Chemokine Receptors And Alpha1-Adrenergic Receptors/Vasopressin Receptor 1A As Drug Targets To Modulate Inflammation And Cell Trafficking
­Advantaages: Novel therapeutic opportunities for modulating inflammation and cell trafficking Insights into neuroendocrine control of immune cell behavior Summary: This innovative technology centers around the discovery and characterization of heteromers formed between chemokine receptors (CR) and a1-adrenergic receptors (AR), specifically...
Published: 8/19/2025   |   Inventor(s): Matthias Majetschak
Keywords(s): Cancer Treatment, Therapeutics Cell Therapy
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Therapeutics