Search Results - xiaoxia+zhu

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Targeting mTOR-Related Autophagy Dysfunction to Treat Age-Related Hearing Loss with Rapamycin and Its Derivatives
Advantages: Novel Application of FDA approved drugs, rapamycin and its derivatives, for treating age-related hearing loss (ARHL). Targeting mTOR alleviates oxidative stress and inflammation in the cochlea, enhancing cellular health and resilience to age-related damage. Potential to Reverse or Delay Age-related hearing loss (ARHL) in patients. Summary: Age-related...
Published: 11/5/2024   |   Inventor(s): Robert Frisina, Xiaohua Zhu, Bo Ding, Xiaoxia Zhu
Keywords(s): Pharmaceuticals, Therapeutics
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices
Molecular Imaging of the Cochlea
­Advantages: Microenvironment Sensitivity: Unveils subtle structural changes within the cochlear microenvironment, enhancing auditory health understanding. Treatment Response Tracking: Precisely quantifies potassium concentration changes, enabling accurate monitoring of treatment responses and disease progression. Non-Invasive Approach: Offers...
Published: 9/11/2024   |   Inventor(s): Parveen Bazard, Mikalai Budzevich, Xiaoxia Zhu, Bo Ding, Robert Frisina
Keywords(s): Diagnostics, Medical Imaging
Category(s): Technology Classifications > Medical > Medical Imaging, Technology Classifications > Medical > Medical Diagnostics
Hormone Treatment for Age-Related Hearing Loss-Presbycusis
­Competitive Advantages Utilizes natural and FDA-approved compounds Suitable for systemic applications Minimal side effects Summary Our researchers have developed a novel drug combination of FDA-approved compounds that achieve significant therapeutic effects in the treatment of ARHL. These compounds include aldosterone, ammonium chloride,...
Published: 8/20/2024   |   Inventor(s): Bo Ding, Joseph Walton, Xiaoxia Zhu, Robert Frisina
Keywords(s):  
Category(s): Technology Classifications > Medical > Pharmaceuticals
A Zero-Restoring Force Reservoir for Fluidic Systems
Competitive Advantages Inexpensive Highly reliable Scalable pump rate Reduced fabrication complexity Summary Our inventors have developed peristaltic micro pumps that are fabricated with direct write printing technologies. The micro-pumps are fabricated such that they are scalable to a broad range of pump rates. These novel...
Published: 9/11/2023   |   Inventor(s): Farzad Forouzandeh, David Borkholder, Robert Frisina, Joseph Walton, Xiaoxia Zhu
Keywords(s): Health Tech, Industrial Applications, Mechanical Engineering, Medical Pharmaceuticals, Medical Pharmaceuticals Drug Delivery Systems
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical, Technology Classifications > Medical > Pharmaceuticals
Fine-Tune Cellulose Crystals in Biocomposites
Morphology change from crystalline (I. Pure Cellulose) to amorphous (III. coagulated in water) or semi-crystalline (IV. coagulated in H2O2) Invention Summary: Natural materials such as cellulose or silk can be used in a multitude of applications such as electrolyte batteries, filters, drug delivery systems and scaffolds for tissue engineering....
Published: 10/21/2024   |   Inventor(s): David Salas-De La Cruz, Xiao Hu, Stacy Love, David Verrill
Keywords(s): Biomaterials, Chemical and petrochemical industry, Membranes, Nanotechnology
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
2018-910 Prediction of Cardiac Arrest Using Continuous Electrocardiogram
SUMMARYUCLA researchers in the Geffen School of Medicine have developed a method to accurately and timely predict cardiac arrest in hospital patients based on a patient’s own data. This method allows for fewer and more relevant alarms that improve the chance of survival from a cardiac arrest episode.BACKGROUNDIn the United States, over 200,000...
Published: 7/19/2023   |   Inventor(s): Duc Do, Noel Boyle, Alan Kuo, Xiao Hu
Keywords(s):  
Category(s): Software & Algorithms > Digital Health, Medical Devices > Monitoring And Recording Systems, Therapeutics > Cardiovascular
Methods of Modifying Cellulose Crystallinity
The use of biomaterials has grown in recent years as applications in the packaging materials, automotive, construction and the biomedical fields has increased. Cellulose, the most widely available natural polymer on earth has significant potential for use in biomaterial applications because it is renewable, more environmentally friendly and less costly...
Published: 9/27/2024   |   Inventor(s): Xiao Hu, David Salas de la Cruz, Stacy Love, David Verrill
Keywords(s): Biomaterials, Biorenewable, Cellulose, Chemistry
Category(s): Engineering > Materials
Neurostimulation Device for the Treatment of Chronic Pain
Chronic pain is a common, complex, and distressing problem that afflicts more than 20 percent (50 million) of the population in the United States and more than 1.9 billion people worldwide. The condition arises from a series of events or injuries, including but not limited to traumatic injury, obesity, congenital disorders, nerve damage and sports injuries....
Published: 11/1/2024   |   Inventor(s): Xue Wei, Jeffrey Hettinger, Xiao Hu, Robert Hirsh
Keywords(s): Biocompatible, Inflammation, Neurostimulation, Pain, Polymers, Protein
Category(s): Human Health Care > Medical Devices
Fabrication of Air-spun Mori silk-TiO2 Nanofibers for Filtration Applications
TechnologyThe disclosure provides a method, apparatus, and collection to produce micro and nanofibers from an adjustable concentric nozzle. This technique consists of the extrusion of protein solution into an evaporative atmosphere to product nanofibers. Previous solution blow techniques focus on the use and generation of synthetic polymers. This details...
Published: 3/6/2024   |   Inventor(s): Xiao Hu, Xiaoyang Mou
Keywords(s): Extrusion, Fabrics, Filtration, Nanofibers, Nonwovens
Category(s): Engineering > Materials
2005-242 Noninvasive Intracranial Pressure Assessment
Non-invasive Assessment of Intracranial PressureBACKGROUNDIntracranial pressure (ICP) is the pressure exerted by cerebral spinal fluid in the cranium. Elevated ICP can lead to hypertension and respiratory changes, among other things. Established means of measuring ICP rely on invasive, direct procedures that provide access to intracranial space. Despite...
Published: 7/19/2023   |   Inventor(s): Xiao Hu, Neil Martin, Valeriy Nenov
Keywords(s): Bioinformatics, Cns, Diagnostic Markers & Platforms, Medical Devices and Materials, Monitoring And Recording Systems
Category(s): Diagnostic Markers, Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics > CNS and Neurology, Software & Algorithms > Bioinformatics
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