Search Results - frank+middleton

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Rapid, robust, and near point-of-care saliva-based nucleic acid detection of dengue virus infections
This technology enables rapid, non-invasive detection and differentiation of all four dengue virus serotypes using saliva samples, with advanced qPCR and RT-LAMP assays, making dengue diagnosis easier, faster, and more accessible without the need for blood draws. Background: Dengue virus (DENV) is a major global health concern, with hundreds of millions...
Published: 1/29/2026   |   Inventor(s): Frank Middleton, Stephen Thomas, Adam Waickman, Timothy Rooney
Keywords(s): diagnostics, disease diagnosis, isothermal amplification (LAMP), nucleic acid, PCR, RNA viruses, saliva, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Screens and Assays, Technology Classifications > Biomedical Science and Engineering
Multiplexed Saliva-based Immunodiagnostics for Assessing Anti-flavivirus Immunity
An easy-to-use method for rapidly, accurately, and non-invasively assessing flavivirus immunity by measuring various antibody classes present in saliva. Background: Flaviviruses (including dengue virus) are the most common vector-borne human viral pathogens in the world. Nearly 40% of the world’s population are at risk of infection with dengue...
Published: 1/29/2026   |   Inventor(s): Adam Waickman, Stephen Thomas, Frank Middleton
Keywords(s): antibodies, antibody, infectious diseases, saliva, Technologies, viral immunology
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
Biomarker Diagnostic for Crohn's Disease Severity
A novel messenger RNA transcript for prediction of ulcerative colitis and Crohn's disease severity. Background: More than 2 million individuals are diagnosed with Crohn's Disease (CD) and Ulcerative Colitis (UC) in the US every year. While much progress has been made in understanding these diseases, the causes are not fully known and effective...
Published: 5/13/2025   |   Inventor(s): William Kerr, Frank Middleton, Sandra Denney
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Campus > Upstate Medical University