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Search Results - andrey+ivanov
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MKK3/MYC Protein-Protein Interaction Inhibitor Overcomes Resistant Non-Small Cell Lung Cancer
Application A therapeutic use for SGI-1027 in the treatment of Osimertinib-resistant non-small cell lung cancer (NSCLC). Key Benefits The MKK3/MYC protein-protein interaction inhibitor SGI-1027 effectively decreases MYC levels in Osimertinib-resistant NSCLC cell lines. The combination of SGI-1027 with Osimertinib offers synergistic benefits over...
Published: 10/3/2025
|
Inventor(s):
Andrey Ivanov
,
Haian Fu
,
Shi-Yong Sun
,
Zhen Chen
Keywords(s):
Drug Discovery
,
Oncology Treatments
,
Protein and Peptide Therapeutics
Category(s):
TechPub Algolia > Therapeutics
METHODS AND SYSTEM FOR SPECTRAL IMAGING OF DENSITY, ANISTROPY, AND ORIENTATION
METHODS AND SYSTEM FOR SPECTRAL IMAGING OF DENSITY, ANISTROPY, AND ORIENTATION Researchers at the Chan Zuckerberg Biohub have developed an imaging module and computational algorithms for high-speed spectral quantitative imaging of density and anisotropy in fluorescence and label-free contrasts. Microscopy is central to biological research and...
Published: 1/31/2025
|
Inventor(s):
Shalin Mehta
,
Ivan Ivanov
,
Li-Hao Yeh
Keywords(s):
Anisotropy
,
Biomolecules
,
Density
,
Microscopy
,
Optical Imaging
,
Polarization
Category(s):
Technology Classifications > Engineering
METHOD AND SYSTEM FOR QUANTITATIVE THREE-DIMENSIONAL MEASUREMENT OF DENSITY, ANISOTROPY, AND ORIENTATION WITHOUT LABEL
METHOD AND SYSTEM FOR QUANTITATIVE THREE-DIMENSIONAL MEASUREMENT OF DENSITY, ANISOTROPY, AND ORIENTATION WITHOUT LABEL Researchers at the Chan Zuckerberg Biohub have developed a label-free computational imaging method for measuring optical properties of a specimen. Biological architecture is intrinsically tensorial. The permittivity tensor (PT)...
Published: 1/31/2025
|
Inventor(s):
Shalin Mehta
,
Ivan Ivanov
,
Li-Hao Yeh
Keywords(s):
Anisotropy
,
Biomolecules
,
Density
,
Microscopy
,
Optical Imaging
,
Polarization
Category(s):
Technology Classifications > Engineering