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Search Results - radhika+amaradhi
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Molecules Targeting Inflammatory Signaling
Application A group of small molecules for treating central and peripheral diseases associated with inflammation. Key Benefits Applicable to a wide variety of central nervous system and peripheral diseases. Can bypass side effects of existing therapeutics targeting similar inflammatory pathways. High target selectivity and aqueous solubility. Capability...
Published: 11/13/2025
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Inventor(s):
Raymond (Ray) Dingledine
,
Radhika Amaradhi
,
Shabber Mohammed
,
Thota Ganesh
Keywords(s):
Immunology and Inflammation Treatments
,
Neurology and Pain Treatments
,
Oncology Treatments
,
Small Molecule
,
Women's Health
Category(s):
TechPub Algolia > Drug Discovery
,
TechPub Algolia > Therapeutics
Quinazolin-4(3H)-one Derivatives as NOX-2 Inhibitors: Composition of Matter, Methods of Preparation and Their Use
Application Quinazolin-4(3H)-one derivatives as selective NOX-2 inhibitors to prevent oxidative damage. Key Benefits Small molecule NOX-2 specific inhibitor. Prevents excessive reactive oxygen species (ROS) generation rather than removing them. Selective NOX-2 inhibition offers significant advantages to development of an effective therapy against...
Published: 11/7/2025
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Inventor(s):
Thota Ganesh
,
Radhika Amaradhi
,
Jacek Zielonka
Keywords(s):
Respiratory Treatments
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics