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Search Results - jia+nong
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Nanoparticles for Precise & Targeted Treatment of Neurological Conditions
Problem: Acute ischemic stroke (AIS) is the second leading cause of death worldwide, affecting around 600,000 Americans annually. However, pharmacological treatment of AIS is difficult due to ineffective and nonspecific targeting to blood brain barrier epitopes via intravenous administration. Over 100 drugs have been tried and failed in clinical trials...
Published: 2/20/2025
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Inventor(s):
Oscar Marcos Contreras
,
Jacob Brenner
,
Vladimir Muzykantov
,
Jia Nong
,
Patrick Glassman
,
Drew Weissman
,
Sahiley Reyes-Esteves
Keywords(s):
Drug Delivery
,
Inflammation
,
Nanotechnology
,
Neurology
Category(s):
Technology Classifications > Therapeutics
Multifunctional nanoparticles for prevention and treatment of atherosclerosis
PAGE TITLE Overview PAGE SUMMARY Atherosclerosis is a chronic inflammatory disease of the artery wall and a major cause of cardiovascular disease, the leading cause of death in the US and many developed economies. The inflamed cells release free radicals that produce a strong local oxidative environment where low density lipoproteins (LDLs) are...
Published: 2/19/2025
|
Inventor(s):
Yinghui Zhong
,
Jia Nong
,
Zhicheng Wang
Keywords(s):
Category(s):
Pharmaceuticals & Therapeutics
,
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...
Published: 3/23/2023
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Inventor(s):
Chung-Jen (James) Chou
,
Ying Mei
,
Jia Jia
Keywords(s):
Category(s):
BioPharma